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Single-molecule characterization of subtype-specific beta1 integrin mechanics.
Jo MH, Li J, Jaumouille V, Hao Y, Coppola J, Yan J, Waterman CM, Springer TA, Ha T
Nat Commun. 2022 Dec 3;13(1):7471. doi: 10.1038/s41467-022-35173-w.
PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.

Antibodies from Article

ID Antibody Purpose
209611 Anti-Integrin alpha 5 beta 1 [IPI-ITGA5/ITGB1.2] Anti-Integrin α5β1 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213652 Anti-Integrin alpha 5 beta 1 [IPI-ITGA5/ITGB1.4] Anti-Integrin α5β1 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213653 Anti-Integrin alpha V beta 8 [IPI-ITGAV/ITGB8.1] Anti-Integrin αVβ8 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213659 Anti-Integrin alpha V beta 5 [IPI-ITGAV/ITGB5.9] Anti-Integrin αVβ5 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)
213660 Anti-Integrin alpha V beta 3 [IPI-ITGAV/ITGB3.7] Anti-Integrin αVβ3 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)
213661 Anti-Integrin alpha V beta 3 [IPI-ITGAV/ITGB3.13] Anti-Integrin αVβ3 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)