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alpha-Synuclein fibril and synaptic vesicle interactions lead to vesicle destruction and increased lipid-associated fibril uptake into iPSC-derived neurons.

Stephens AD, Villegas AF, Chung CW, Vanderpoorten O, Pinotsi D, Mela I, Ward E, McCoy TM, Cubitt R, Routh AF, Kaminski CF, Kaminski Schierle GS
Commun Biol. 2023 May 15;6(1):526. doi: 10.1038/s42003-023-04884-1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
108866pT7-7 aSyn C141Expresses human WT alpha synuclein with a C-terminal cysteine

Antibodies from Article