Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death.
Gross A, Yin XM, Wang K, Wei MC, Jockel J, Milliman C, Erdjument-Bromage H, Tempst P, Korsmeyer SJ
J Biol Chem 1999 Jan 8;274(2):1156-63.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 8771 | 3405 pBM272 Bid p22 | |
| 8807 | 3389 pcDNA3 Bid p22 | |
| 8808 | 3392 pcDNA3 Bid p15 |