pcDNA3-myc-Skp2 Citations (8)
Originally described in: Phosphorylation- and Skp1-independent in vitro ubiquitination of E2F1 by multiple ROC-cullin ligases.Ohta T, Xiong Y Cancer Res. 2001 Feb 15. 61(4):1347-53. PubMed
Articles Citing pcDNA3-myc-Skp2
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SOX9 inhibits beta-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.
Deng W, Vanderbilt DB, Lin CC, Martin KH, Brundage KM, Ruppert JM.
J Cell Sci. 2015 Jan 27. pii: jcs.162164.
PubMed
Associated Plasmids |
| Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model. Li X, Yokoyama NN, Zhang S, Ding L, Liu HM, Lilly MB, Mercola D, Zi X. Oncotarget. 2015 Dec 8;6(39):41809-24. doi: 10.18632/oncotarget.6166. PubMed |
| A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival. Cheng Y, Wang Y, Li J, Chang I, Wang CY. Oncotarget. 2017 Jan 10;8(2):1972-1982. doi: 10.18632/oncotarget.14081. PubMed |
| SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton BN, Chang L, Liu N, Zeng L, Wang W, Wang Y, Zhang P, Hu X, Su X, Liang H, Sun Y, Ma L. Nat Commun. 2018 Jun 11;9(1):2269. doi: 10.1038/s41467-018-04620-y. PubMed |
| E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding. Allegre J, Cartier J, Glorian V, Droin N, Dumetier B, Kayaci C, Berthelet J, Gemble S, Vuillier C, Maillet L, Garrido C, Dubrez L. PLoS One. 2018 Oct 25;13(10):e0206253. doi: 10.1371/journal.pone.0206253. eCollection 2018. PubMed |
| Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation. Li X, Pham V, Tippin M, Fu D, Rendon R, Song L, Uchio E, Hoang BH, Zi X. Cell Commun Signal. 2019 Mar 18;17(1):25. doi: 10.1186/s12964-019-0338-2. PubMed |
| High Skp2 expression is associated with a mesenchymal phenotype and increased tumorigenic potential of prostate cancer cells. Simeckova S, Kahounova Z, Fedr R, Remsik J, Slabakova E, Suchankova T, Prochazkova J, Bouchal J, Kharaishvili G, Kral M, Benes P, Soucek K. Sci Rep. 2019 Apr 5;9(1):5695. doi: 10.1038/s41598-019-42131-y. PubMed |
| SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. Gassen NC, Niemeyer D, Muth D, Corman VM, Martinelli S, Gassen A, Hafner K, Papies J, Mosbauer K, Zellner A, Zannas AS, Herrmann A, Holsboer F, Brack-Werner R, Boshart M, Muller-Myhsok B, Drosten C, Muller MA, Rein T. Nat Commun. 2019 Dec 18;10(1):5770. doi: 10.1038/s41467-019-13659-4. PubMed |
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