Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pRosa26-DEST Citations (15)

Originally described in: High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi.
Hohenstein P, Slight J, Ozdemir DD, Burn SF, Berry R, Hastie ND Pathogenetics. 2008 . 1(1):3.
PubMed Journal

Articles Citing pRosa26-DEST

Articles
A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells. Chakraborty S, Christoforou N, Fattahi A, Herzog RW, Leong KW. PLoS One. 2013 May 22;8(5):e64342. doi: 10.1371/journal.pone.0064342. Print 2013. PubMed
An inducible CiliaGFP mouse model for in vivo visualization and analysis of cilia in live tissue. O'Connor AK, Malarkey EB, Berbari NF, Croyle MJ, Haycraft CJ, Bell PD, Hohenstein P, Kesterson RA, Yoder BK. Cilia. 2013 Jul 3;2(1):8. doi: 10.1186/2046-2530-2-8. PubMed
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). Carofino BL, Ayanga B, Justice MJ. Dis Model Mech. 2013 Nov;6(6):1494-506. doi: 10.1242/dmm.012575. Epub 2013 Sep 5. PubMed
Tissue-Specific Regulation of Oncogene Expression Using Cre-Inducible ROSA26 Knock-In Transgenic Mice. Carofino BL, Justice MJ. Curr Protoc Mouse Biol. 2015 Jun 1;5(2):187-204. doi: 10.1002/9780470942390.mo140150. PubMed
Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury. Bolisetty S, Traylor A, Joseph R, Zarjou A, Agarwal A. Am J Physiol Renal Physiol. 2016 Mar 1;310(5):F385-94. doi: 10.1152/ajprenal.00335.2015. Epub 2015 Dec 16. PubMed
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype. Schultz MJ, Holdbrooks AT, Chakraborty A, Grizzle WE, Landen CN, Buchsbaum DJ, Conner MG, Arend RC, Yoon KJ, Klug CA, Bullard DC, Kesterson RA, Oliver PG, O'Connor AK, Yoder BK, Bellis SL. Cancer Res. 2016 Jul 1;76(13):3978-88. doi: 10.1158/0008-5472.CAN-15-2834. Epub 2016 May 23. PubMed
Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression. Dharmadhikari AV, Sun JJ, Gogolewski K, Carofino BL, Ustiyan V, Hill M, Majewski T, Szafranski P, Justice MJ, Ray RS, Dickinson ME, Kalinichenko VV, Gambin A, Stankiewicz P. Biol Open. 2016 Nov 15;5(11):1595-1606. doi: 10.1242/bio.019208. PubMed
Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice. Wei Y, Chhiba KD, Zhang F, Ye X, Wang L, Zhang L, Robida PA, Moreno-Vinasco L, Schnaar RL, Roers A, Hartmann K, Lee CM, Demers D, Zheng T, Bochner BS, Zhu Z. Int J Mol Sci. 2018 Dec 21;20(1). pii: ijms20010019. doi: 10.3390/ijms20010019. PubMed
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice. Weber J, de la Rosa J, Grove CS, Schick M, Rad L, Baranov O, Strong A, Pfaus A, Friedrich MJ, Engleitner T, Lersch R, Ollinger R, Grau M, Menendez IG, Martella M, Kohlhofer U, Banerjee R, Turchaninova MA, Scherger A, Hoffman GJ, Hess J, Kuhn LB, Ammon T, Kim J, Schneider G, Unger K, Zimber-Strobl U, Heikenwalder M, Schmidt-Supprian M, Yang F, Saur D, Liu P, Steiger K, Chudakov DM, Lenz G, Quintanilla-Martinez L, Keller U, Vassiliou GS, Cadinanos J, Bradley A, Rad R. Nat Commun. 2019 Mar 29;10(1):1415. doi: 10.1038/s41467-019-09180-3. PubMed
TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease. Baba M, Furuya M, Motoshima T, Lang M, Funasaki S, Ma W, Sun HW, Hasumi H, Huang Y, Kato I, Kadomatsu T, Satou Y, Morris N, Karim BO, Ileva L, Kalen JD, Wilan Krisna LA, Hasumi Y, Sugiyama A, Kurahashi R, Nishimoto K, Oyama M, Nagashima Y, Kuroda N, Araki K, Eto M, Yao M, Kamba T, Suda T, Oike Y, Schmidt LS, Linehan WM. Mol Cancer Res. 2019 Aug;17(8):1613-1626. doi: 10.1158/1541-7786.MCR-18-1235. Epub 2019 May 1. PubMed
DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, Ozawa M, Saitou M, Shinkai Y, Yamamoto T, Yamada Y. Nat Commun. 2021 Aug 19;12(1):5041. doi: 10.1038/s41467-021-25249-4. PubMed
Enhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytes. Saito Y, Nakamura K, Yoshida M, Sugiyama H, Akagi S, Miyoshi T, Morita H, Ito H. Stem Cell Res Ther. 2022 Apr 1;13(1):141. doi: 10.1186/s13287-022-02818-y. PubMed
Efficient simultaneous double DNA knock-in in murine embryonic stem cells by CRISPR/Cas9 ribonucleoprotein-mediated circular plasmid targeting for generating gene-manipulated mice. Ozawa M, Taguchi J, Katsuma K, Ishikawa-Yamauchi Y, Kikuchi M, Sakamoto R, Yamada Y, Ikawa M. Sci Rep. 2022 Dec 13;12(1):21558. doi: 10.1038/s41598-022-26107-z. PubMed
The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion. Onuchic L, Padovano V, Schena G, Rajendran V, Dong K, Shi X, Pandya R, Rai V, Gresko NP, Ahmed O, Lam TT, Wang W, Shen H, Somlo S, Caplan MJ. Nat Commun. 2023 Mar 30;14(1):1790. doi: 10.1038/s41467-023-37449-1. PubMed
SMYD5 is a novel epigenetic gatekeeper of the mild hypothermia response. Rafnsdottir S, Jang K, Halldorsdottir ST, Tomasdottir A, Vinod M, Moller K, Reynisdottir T, Atladottir LH, Allison KE, He J, Zhang L, Northington FJ, Chavez-Valdez R, Anderson KJ, Bjornsson HT. bioRxiv. 2023 Jun 9:2023.05.11.540170. doi: 10.1101/2023.05.11.540170. Preprint. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.