Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pCMV-Flag-YAP-5SA/S94A Citations (13)

Originally described in: TEAD mediates YAP-dependent gene induction and growth control.
Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL Genes Dev. 2008 Jul 15. 22(14):1962-71.
PubMed Journal

Articles Citing pCMV-Flag-YAP-5SA/S94A

Articles
A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells. Qu L, Wu Z, Li Y, Xu Z, Liu B, Liu F, Bao Y, Wu D, Liu J, Wang A, Chu X, Sun Y, Chen C, Zhang Z, Wang L. Nat Commun. 2016 Nov 25;7:12692. doi: 10.1038/ncomms12692. PubMed
YAP Tyrosine Phosphorylation and Nuclear Localization in Cholangiocarcinoma Cells Are Regulated by LCK and Independent of LATS Activity. Sugihara T, Werneburg NW, Hernandez MC, Yang L, Kabashima A, Hirsova P, Yohanathan L, Sosa C, Truty MJ, Vasmatzis G, Gores GJ, Smoot RL. Mol Cancer Res. 2018 Oct;16(10):1556-1567. doi: 10.1158/1541-7786.MCR-18-0158. Epub 2018 Jun 14. PubMed
Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Pavel M, Renna M, Park SJ, Menzies FM, Ricketts T, Fullgrabe J, Ashkenazi A, Frake RA, Lombarte AC, Bento CF, Franze K, Rubinsztein DC. Nat Commun. 2018 Jul 27;9(1):2961. doi: 10.1038/s41467-018-05388-x. PubMed
The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Lavado A, Park JY, Pare J, Finkelstein D, Pan H, Xu B, Fan Y, Kumar RP, Neale G, Kwak YD, McKinnon PJ, Johnson RL, Cao X. Dev Cell. 2018 Dec 3;47(5):576-591.e8. doi: 10.1016/j.devcel.2018.09.021. Epub 2018 Oct 25. PubMed
Substrate mechanics controls adipogenesis through YAP phosphorylation by dictating cell spreading. Oliver-De La Cruz J, Nardone G, Vrbsky J, Pompeiano A, Perestrelo AR, Capradossi F, Melajova K, Filipensky P, Forte G. Biomaterials. 2019 Jun;205:64-80. doi: 10.1016/j.biomaterials.2019.03.009. Epub 2019 Mar 16. PubMed
Metabolic Reprogramming Promotes Neural Crest Migration via Yap/Tead Signaling. Bhattacharya D, Azambuja AP, Simoes-Costa M. Dev Cell. 2020 Apr 20;53(2):199-211.e6. doi: 10.1016/j.devcel.2020.03.005. Epub 2020 Apr 2. PubMed
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis. Li L, Ugalde AP, Scheele CLGJ, Dieter SM, Nagel R, Ma J, Pataskar A, Korkmaz G, Elkon R, Chien MP, You L, Su PR, Bleijerveld OB, Altelaar M, Momchev L, Manber Z, Han R, van Breugel PC, Lopes R, Ten Dijke P, van Rheenen J, Agami R. Genome Biol. 2021 Jan 29;22(1):54. doi: 10.1186/s13059-021-02272-8. PubMed
The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. Yang WH, Lin CC, Wu J, Chao PY, Chen K, Chen PH, Chi JT. Mol Cancer Res. 2021 Jun;19(6):1005-1014. doi: 10.1158/1541-7786.MCR-20-0534. Epub 2021 Mar 11. PubMed
Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells. Van Sciver N, Ohashi M, Pauly NP, Bristol JA, Nelson SE, Johannsen EC, Kenney SC. PLoS Pathog. 2021 Aug 2;17(8):e1009783. doi: 10.1371/journal.ppat.1009783. eCollection 2021 Aug. PubMed
YAP/TAZ drives cell proliferation and tumour growth via a polyamine-eIF5A hypusination-LSD1 axis. Li H, Wu BK, Kanchwala M, Cai J, Wang L, Xing C, Zheng Y, Pan D. Nat Cell Biol. 2022 Mar;24(3):373-383. doi: 10.1038/s41556-022-00848-5. Epub 2022 Feb 17. PubMed
RhoA-ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic-like flow. Mohammadalipour A, Diaz MF, Livingston M, Ewere A, Zhou A, Horton PD, Olamigoke LT, Lamar JM, Hagan JP, Lee HJ, Wenzel PL. FASEB Bioadv. 2022 Feb 14;4(5):342-361. doi: 10.1096/fba.2021-00055. eCollection 2022 May. PubMed
Structure-based discovery of a novel small-molecule inhibitor of TEAD palmitoylation with anticancer activity. Gridnev A, Maity S, Misra JR. Front Oncol. 2022 Nov 29;12:1021823. doi: 10.3389/fonc.2022.1021823. eCollection 2022. PubMed
Mechanical control of the mammalian circadian clock via YAP/TAZ and TEAD. Abenza JF, Rossetti L, Mouelhi M, Burgues J, Andreu I, Kennedy K, Roca-Cusachs P, Marco S, Garcia-Ojalvo J, Trepat X. J Cell Biol. 2023 Sep 4;222(9):e202209120. doi: 10.1083/jcb.202209120. Epub 2023 Jun 28. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.