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GRK2-K220R Citations (3)

Originally described in: Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
Freedman NJ, Liggett SB, Drachman DE, Pei G, Caron MG, Lefkowitz RJ J Biol Chem. 1995 Jul 28;270(30):17953-61.
PubMed Journal

Articles Citing GRK2-K220R

Articles
The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation. Pack TF, Orlen MI, Ray C, Peterson SM, Caron MG. J Biol Chem. 2018 Apr 20;293(16):6161-6171. doi: 10.1074/jbc.RA117.001300. Epub 2018 Feb 27. PubMed
GRK2 mediates beta-arrestin interactions with 5-HT2 receptors for JC polyomavirus endocytosis. Mayberry CL, Wilczek MP, Fong TM, Nichols SL, Maginnis MS. J Virol. 2021 Jan 13. pii: JVI.02139-20. doi: 10.1128/JVI.02139-20. PubMed
MRAP2 inhibits beta-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation. Rouault AAJ, Buscaglia P, Sebag JA. J Biol Chem. 2022 Jun;298(6):102057. doi: 10.1016/j.jbc.2022.102057. Epub 2022 May 20. PubMed

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