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pCMV-Tag2B EDD C2768A Citations (5)

Originally described in: EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response.
Henderson MJ, Russell AJ, Hird S, Munoz M, Clancy JL, Lehrbach GM, Calanni ST, Jans DA, Sutherland RL, Watts CK J Biol Chem. 2002 Jul 19;277(29):26468-78. Epub 2002 May 13.
PubMed Journal

Articles Citing pCMV-Tag2B EDD C2768A

Articles
A functional genomic approach reveals the transcriptional role of EDD in the expression and function of angiogenesis regulator ACVRL1. Chen HW, Yang CC, Hsieh CL, Liu H, Lee SC, Tan BC. Biochim Biophys Acta. 2013 Dec;1829(12):1309-19. doi: 10.1016/j.bbagrm.2013.10.006. Epub 2013 Nov 2. PubMed
E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60. Subbaiah VK, Zhang Y, Rajagopalan D, Abdullah LN, Yeo-Teh NS, Tomaic V, Banks L, Myers MP, Chow EK, Jha S. Oncogene. 2015 Aug 3. doi: 10.1038/onc.2015.268. PubMed
E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer. Liao L, Song M, Li X, Tang L, Zhang T, Zhang L, Pan Y, Chouchane L, Ma X. Cancer Res. 2017 Apr 15;77(8):2090-2101. doi: 10.1158/0008-5472.CAN-16-2409. Epub 2017 Mar 22. PubMed
The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease. Dhingani N, Guo C, Pan J, Li Q, Warner N, Jardine S, Leung G, Kotlarz D, Gonzaga-Jauregui C, Klein C, Snapper SB, Navas-Lopez VM, Muise AM. Sci Rep. 2020 Oct 29;10(1):18648. doi: 10.1038/s41598-020-73482-6. PubMed
Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Song M, Yeku OO, Rafiq S, Purdon T, Dong X, Zhu L, Zhang T, Wang H, Yu Z, Mai J, Shen H, Nixon B, Li M, Brentjens RJ, Ma X. Nat Commun. 2020 Dec 8;11(1):6298. doi: 10.1038/s41467-020-20140-0. PubMed

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