Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pCI-Caspase 1 Citations (4)

Originally described in: AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA Nature. 2009 Mar 26. 458(7237):514-8.
PubMed Journal

Articles Citing pCI-Caspase 1

Articles
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation. Zhong FL, Mamai O, Sborgi L, Boussofara L, Hopkins R, Robinson K, Szeverenyi I, Takeichi T, Balaji R, Lau A, Tye H, Roy K, Bonnard C, Ahl PJ, Jones LA, Baker P, Lacina L, Otsuka A, Fournie PR, Malecaze F, Lane EB, Akiyama M, Kabashima K, Connolly JE, Masters SL, Soler VJ, Omar SS, McGrath JA, Nedelcu R, Gribaa M, Denguezli M, Saad A, Hiller S, Reversade B. Cell. 2016 Sep 22;167(1):187-202.e17. doi: 10.1016/j.cell.2016.09.001. PubMed
Caspase-1 regulates cellular trafficking via cleavage of the Rab7 adaptor protein RILP. Adams A, Weinman SA, Wozniak AL. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2619-2624. doi: 10.1016/j.bbrc.2018.08.013. Epub 2018 Aug 9. PubMed
Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes. Mambwe B, Neo K, Javanmard Khameneh H, Leong KWK, Colantuoni M, Vacca M, Muimo R, Mortellaro A. Front Immunol. 2019 Jul 5;10:1556. doi: 10.3389/fimmu.2019.01556. eCollection 2019. PubMed
Complementary regulation of caspase-1 and IL-1beta reveals additional mechanisms of dampened inflammation in bats. Goh G, Ahn M, Zhu F, Lee LB, Luo D, Irving AT, Wang LF. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28939-28949. doi: 10.1073/pnas.2003352117. Epub 2020 Oct 26. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.