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pGEX6P2-MDM2 (17-125) Citations (3)

Originally described in: Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
Borcherds W, Theillet FX, Katzer A, Finzel A, Mishall KM, Powell AT, Wu H, Manieri W, Dieterich C, Selenko P, Loewer A, Daughdrill GW Nat Chem Biol. 2014 Dec;10(12):1000-2. doi: 10.1038/nchembio.1668. Epub 2014 Nov 2.
PubMed Journal

Articles Citing pGEX6P2-MDM2 (17-125)

Articles
Isolation of a peptide containing d-amino acid residues that inhibits the alpha-helix-mediated p53-MDM2 interaction from a one-bead one-compound library. Morimoto J, Hosono Y, Sando S. Bioorg Med Chem Lett. 2018 Jan 2. pii: S0960-894X(18)30001-5. doi: 10.1016/j.bmcl.2018.01.001. PubMed
S100A1 blocks the interaction between p53 and mdm2 and decreases cell proliferation activity. Dowarha D, Chou RH, Yu C. PLoS One. 2020 Jun 4;15(6):e0234152. doi: 10.1371/journal.pone.0234152. eCollection 2020. PubMed
Cancer-Associated Mutations Perturb the Disordered Ensemble and Interactions of the Intrinsically Disordered p53 Transactivation Domain. Schrag LG, Liu X, Thevarajan I, Prakash O, Zolkiewski M, Chen J. J Mol Biol. 2021 Jul 23;433(15):167048. doi: 10.1016/j.jmb.2021.167048. Epub 2021 May 11. PubMed

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