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Bert Vogelstein Lab Plasmids


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Title Authors Publication
A bacterial protein enhances the release and efficacy of liposomal cancer drugs. Cheong I, Huang X, Bettegowda C, Diaz LA, Kinzler KW, Zhou S, Vogelstein B Science. 2006 Nov 24. 314(5803):1308-11.
The colorectal microRNAome. Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 2006 Mar 7. 103(10):3687-92.
Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Samuels Y, Diaz LA, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE Cancer Cell. 2005 Jun . 7(6):561-73.
Mutational analysis of the tyrosine phosphatome in colorectal cancers. Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE Science. 2004 May 21. 304(5674):1164-6.
HAUSP is required for p53 destabilization. Cummins JM, Vogelstein B Cell Cycle. 2004 Jun . 3(6):689-92.
High frequency of mutations of the PIK3CA gene in human cancers. Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE Science. 2004 Apr 23. 304(5670):554.
Inactivation of hCDC4 can cause chromosomal instability. Rajagopalan H, Jallepalli PV, Rago C, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C Nature. 2004 Mar 4. 428(6978):77-81.
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Kohli M, Rago C, Lengauer C, Kinzler KW, Vogelstein B Nucleic Acids Res. 2004 . 32(1):e3.
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee I, Bachman KE, Park BH, Jair KW, Yen RW, Schuebel KE, Cui H, Feinberg AP, Lengauer C, Kinzler KW, Baylin SB, Vogelstein B Nature. 2002 Apr 4. 416(6880):552-6.
DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Zawel L, Yu J, Torrance CJ, Markowitz S, Kinzler KW, Vogelstein B, Zhou S Proc Natl Acad Sci U S A. 2002 Mar 5. 99(5):2848-53.
A phosphatase associated with metastasis of colorectal cancer. Saha S, Bardelli A, Buckhaults P, Velculescu VE, Rago C, St Croix B, Romans KE, Choti MA, Lengauer C, Kinzler KW, Vogelstein B Science. 2001 Nov 9. 294(5545):1343-6.
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RA, Kinzler KW, Vogelstein B Nat Med. 2001 Oct . 7(10):1111-7.
Use of isogenic human cancer cells for high-throughput screening and drug discovery. Torrance CJ, Agrawal V, Vogelstein B, Kinzler KW Nat Biotechnol. 2001 Oct . 19(10):940-5.
Cell surface tumor endothelial markers are conserved in mice and humans. Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B Cancer Res. 2001 Sep 15. 61(18):6649-55.
PUMA induces the rapid apoptosis of colorectal cancer cells. Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B Mol Cell. 2001 Mar . 7(3):673-82.
Securin is required for chromosomal stability in human cells. Jallepalli PV, Waizenegger IC, Bunz F, Langer S, Speicher MR, Peters JM, Kinzler KW, Vogelstein B, Lengauer C Cell. 2001 May 18. 105(4):445-57.
Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Park BH, Vogelstein B, Kinzler KW Proc Natl Acad Sci U S A. 2001 Feb 27. 98(5):2598-603.
Role of BAX in the apoptotic response to anticancer agents. Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B Science. 2000 Nov 3. 290(5493):989-92.
Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropin. Shih IM, Torrance C, Sokoll LJ, Chan DW, Kinzler KW, Vogelstein B Nat Med. 2000 Jun . 6(6):711-4.
The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Shih IM, Yu J, He TC, Vogelstein B, Kinzler KW Cancer Res. 2000 Mar 15. 60(6):1671-6.
Identification of CDK4 as a target of c-MYC. Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett JF, Obaya AJ, O'Connell BC, Mateyak MK, Tam W, Kohlhuber F, Dang CV, Sedivy JM, Eick D, Vogelstein B, Kinzler KW Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34.
Identification and classification of p53-regulated genes. Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B Proc Natl Acad Sci U S A. 1999 Dec 7. 96(25):14517-22.
PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He TC, Chan TA, Vogelstein B, Kinzler KW Cell. 1999 Oct 29. 99(3):335-45.
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B Nature. 1999 Oct 7. 401(6753):616-20.
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. da Costa LT, He TC, Yu J, Sparks AB, Morin PJ, Polyak K, Laken S, Vogelstein B, Kinzler KW Oncogene. 1999 Sep 2. 18(35):5010-4.
Identification of c-MYC as a target of the APC pathway. He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW Science. 1998 Sep 4. 281(5382):1509-12.
Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B Mol Cell. 1998 Jul . 2(1):121-7.
Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B, Kern SE Mol Cell. 1998 Mar . 1(4):611-7.
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B Mol Cell. 1997 Dec . 1(1):3-11.
Mutations of mitotic checkpoint genes in human cancers. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B Nature. 1998 Mar 19. 392(6673):300-3.
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Nicolaides NC, Littman SJ, Modrich P, Kinzler KW, Vogelstein B Mol Cell Biol. 1998 Mar . 18(3):1635-41.
A simplified system for generating recombinant adenoviruses. He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14.
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. Zhou S, Buckhaults P, Zawel L, Bunz F, Riggins G, Dai JL, Kern SE, Kinzler KW, Vogelstein B Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2412-6.
A model for p53-induced apoptosis. Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B Nature. 1997 Sep 18. 389(6648):300-5.
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW Science. 1997 Mar 21. 275(5307):1787-90.
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H Science. 1997 Mar 21. 275(5307):1784-7.
Apoptosis and APC in colorectal tumorigenesis. Morin PJ, Vogelstein B, Kinzler KW Proc Natl Acad Sci U S A. 1996 Jul 23. 93(15):7950-4.
Mad-related genes in the human. Riggins GJ, Thiagalingam S, Rozenblum E, Weinstein CL, Kern SE, Hamilton SR, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B Nat Genet. 1996 Jul . 13(3):347-9.
Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. Nicolaides NC, Kinzler KW, Vogelstein B Genomics. 1995 Sep 20. 29(2):329-34.
Converting cancer genes into killer genes. Da Costa LT, Jen J, He TC, Chan TA, Kinzler KW, Vogelstein B Proc Natl Acad Sci U S A. 1996 Apr 30. 93(9):4192-6.
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53. Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B Nature. 1993 Apr 29. 362(6423):857-60.
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Peltomaki P, Sistonen P, Aaltonen LA, Nystroem-Lahti M Cell. 1993 Dec 17. 75(6):1215-25.
WAF1, a potential mediator of p53 tumor suppression. el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B Cell. 1993 Nov 19. 75(4):817-25.
Mutation of a mutL homolog in hereditary colon cancer. Papadopoulos N, Nicolaides NC, Wei YF, Ruben SM, Carter KC, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD Science. 1994 Mar 18. 263(5153):1625-9.
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nicolaides NC, Papadopoulos N, Liu B, Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM Nature. 1994 Sep 1. 371(6492):75-80.
Paradoxical inhibition of solid tumor cell growth by bcl2. Pietenpol JA, Papadopoulos N, Markowitz S, Willson JK, Kinzler KW, Vogelstein B Cancer Res. 1994 Jul 15. 54(14):3714-7.
Deletion of p16 and p15 genes in brain tumors. Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, Willson JK, Kinzler KW, Vogelstein B Cancer Res. 1994 Dec 15. 54(24):6353-8.
Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. Pietenpol JA, Bohlander SK, Sato Y, Papadopoulos N, Liu B, Friedman C, Trask BJ, Roberts JM, Kinzler KW, Rowley JD Cancer Res. 1995 Mar 15. 55(6):1206-10.
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry WS, Tokino T, Waldman T, Oliner JD, Velculescu VE, Burrell M, Hill DE, Healy E, Rees JL, Hamilton SR Cancer Res. 1995 Jul 1. 55(13):2910-9.
APC binds to the novel protein EB1. Su LK, Burrell M, Hill DE, Gyuris J, Brent R, Wiltshire R, Trent J, Vogelstein B, Kinzler KW Cancer Res. 1995 Jul 15. 55(14):2972-7.
PAK1, a gene that can regulate p53 activity in yeast. Thiagalingam S, Kinzler KW, Vogelstein B Proc Natl Acad Sci U S A. 1995 Jun 20. 92(13):6062-6.
The GLI gene is a member of the Kruppel family of zinc finger proteins. Kinzler KW, Ruppert JM, Bigner SH, Vogelstein B Nature. 1988 Mar 24. 332(6162):371-4.
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, vanTuinen P, Ledbetter DH, Barker DF, Nakamura Y, White R, Vogelstein B Science. 1989 Apr 14. 244(4901):217-21.
Identification of a chromosome 18q gene that is altered in colorectal cancers. Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler KW Science. 1990 Jan 5. 247(4938):49-56.
Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker SJ, Markowitz S, Fearon ER, Willson JK, Vogelstein B Science. 1990 Aug 24. 249(4971):912-5.
Amplification of a gene encoding a p53-associated protein in human sarcomas. Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B Nature. 1992 Jul 2. 358(6381):80-3.
Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
pGRE-GFP EGFP Mammalian Expression Converting cancer genes into killer genes. Da et al Proc Natl Acad Sci U S A. 1996 Apr 30. 93(9):4192-6. na Add to Cart
BJ5183 cells BJ5183 bacterial cells A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. n/a Add to Cart
AdEasier-1 cells (strain) AdEasier-1 bacterial cells A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. n/a Add to Cart
pAdEasy-1 Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. Adenoviral vector for use in AdEasy System. pAdEasy and reg-1 Add to Cart
pAdEasy-2 Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. Adenoviral vector for use in AdEasy System, for use with large inserts. pAdEasy-2 Add to Cart
pShuttle Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. Shuttle vector for us in AdEasy System. Used for expression of transgenes under a chosen (non-CMV) promoter when no GFP tracer is desired. pShuttle Add to Cart
pShuttle-CMV Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. Shuttle vector for us in AdEasy System. Used for expression of transgenes under a CMV promoter when no GFP tracer is desired. pShuttle-CMV Add to Cart
pAdTrack Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. Shuttle vector for us in AdEasy System. Used for expression of transgenes under a chosen (non-CMV) promoter when a GFP tracer is desired. pAdTrack Add to Cart
pAdTrack-CMV Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. Shuttle vector for us in AdEasy System. For expression of transgenes under a CMV promoter when a GFP tracer is desired. pAdTrack-CMV Add to Cart
pAdEasy 2-GFP beta-gal beta-galactosidase with stuffer Mammalian Expression, Adenoviral A simplified system for generating recombinant adenoviruses. He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2509-14. pAdEasy-2 Add to Cart
pAAV-Hyg-FHIT FHIT Hyg targeting (Homo sapiens) Mammalian Expression ; adeno-associated viral Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Kohli et al Nucleic Acids Res. 2004 . 32(1):e3. pAAV-MCS FHIT AP3Aase, FRA3B Add to Cart
pAAV-Neo-PTEN PTEN Neo targeting (Homo sapiens) Mammalian Expression ; adeno-associated viral Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Kohli et al Nucleic Acids Res. 2004 . 32(1):e3. pAAV-MCS PTEN 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 Add to Cart
pNeDaKO-Neo PGK-NeoR & ZeoR Mammalian Expression, Cre/Lox Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Kohli et al Nucleic Acids Res. 2004 . 32(1):e3. pBluescript SK+ Add to Cart
pNeDaKO-Hyg PGK-HygR & ZeoR Mammalian Expression, Cre/Lox Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Kohli et al Nucleic Acids Res. 2004 . 32(1):e3. pBluescript SK+ Add to Cart
GLI K12 GLI (Homo sapiens) Bacterial Expression The GLI gene is a member of the Kruppel family of zinc finger proteins. Kinzler et al Nature. 1988 Mar 24. 332(6162):371-4. pBluescript KS GLI1 GLI Add to Cart
GLI-3 bs-2 GLI3 (Homo sapiens) Bacterial Expression The GLI gene is a member of the Kruppel family of zinc finger proteins. Kinzler et al Nature. 1988 Mar 24. 332(6162):371-4. pBluescript SK GLI3 ACLS, GCPS, GLI3-190, GLI3FL, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV Add to Cart
pBSK-SN3 (wt p53) p53 (Homo sapiens) Bacterial Expression Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Baker et al Science. 1989 Apr 14. 244(4901):217-21. pBluescript SK TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam p53 wt p53 (Homo sapiens) Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. pCMV-Neo-Bam TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam p53 V143A p53 V143A (Homo sapiens) Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. pCMV-Neo-Bam TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam p53 R175H p53 R175H (Homo sapiens) Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. pCMV-Neo-Bam TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam p53 R248W p53 R248W (Homo sapiens) Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. pCMV-Neo-Bam TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam p53 R249S p53 R249S (Homo sapiens) Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. pCMV-Neo-Bam TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam p53 R273H p53 R273H (Homo sapiens) Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. pCMV-Neo-Bam TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCMV-Neo-Bam Mammalian Expression Suppression of human colorectal carcinoma cell growth by wild-type p53. Baker et al Science. 1990 Aug 24. 249(4971):912-5. Contains two independent transcription units--a CMV promoter/enhancer upstream of a MCS and a HSV thymidine kinase promoter/enhancer upstream of the neomycin resistance gene. pCMV-Neo-Bam Add to Cart
pCMV MDM-2 MDM2 (Homo sapiens) Mammalian Expression Amplification of a gene encoding a p53-associated protein in human sarcomas. Oliner et al Nature. 1992 Jul 2. 358(6381):80-3. pCMV-Neo-Bam MDM2 ACTFS, HDMX, hdm2 Add to Cart
PG13-luc (wt p53 binding sites) p53-binding site Mammalian Expression, Luciferase WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. Luciferase reporter containing 13 copies of the p53-binding consensus sequence pBluescript II SK + luc TP53 BCC7, LFS1, P53, TRP53 Add to Cart
MG15-luc (mut p53 binding sites) p53-binding site (mutant) Mammalian Expression, Luciferase WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. n/a TP53 BCC7, LFS1, P53, TRP53 Add to Cart
PG13-gal (wt p53 binding sites) p53-binding site Mammalian Expression ; beta-gal reporter WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pBluescript II SK + bgal TP53 BCC7, LFS1, P53, TRP53 Add to Cart
MG15-gal (mut p53 binding sites) p53-binding site (mutant) Mammalian Expression ; beta-gal reporter WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pBluescript II SK + bgal TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pCEP-WAF1-AS WAF1 antisense (Homo sapiens) Mammalian Expression WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pCEP4 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
pCEP-WAF1-ES WAF1 stop codon mut (Homo sapiens) Mammalian Expression WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pCEP4 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
pCEP-WAF1 WAF1 (Homo sapiens) Mammalian Expression WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pCEP4 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
WWP-Luc (p21/WAF1 promoter) WAF1 promoter (Homo sapiens) Mammalian Expression, Luciferase WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pBluescript II KS (+) + luc CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
D3 clone (p21/WAF1 promoter) WAF1 promoter (Homo sapiens) Mammalian Expression WAF1, a potential mediator of p53 tumor suppression. el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25. pBluescript SK(+) CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
hMSH2 Clone E3 (full-length) MSH2 (Homo sapiens) Bacterial Expression Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Leach et al Cell. 1993 Dec 17. 75(6):1215-25. pBluescript SK MSH2 COCA1, FCC1, HNPCC, HNPCC1, LCFS2 Add to Cart
pCRII p15 p15 (Homo sapiens) Bacterial Expression Deletion of p16 and p15 genes in brain tumors. Jen et al Cancer Res. 1994 Dec 15. 54(24):6353-8. pCRII CDKN2B RP11-149I2.1, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b Add to Cart
pCRII p16 p16 (Homo sapiens) Bacterial Expression Deletion of p16 and p15 genes in brain tumors. Jen et al Cancer Res. 1994 Dec 15. 54(24):6353-8. pCRII CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 Add to Cart
pBluescript PMS2 PMS2 (Homo sapiens) Bacterial Expression Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nicolaides et al Nature. 1994 Sep 1. 371(6492):75-80. pBluescript SK PMS2 HNPCC4, PMS2CL, PMSL2 Add to Cart
pCEP9 MLH1 MLH1 (Homo sapiens) Mammalian Expression Mutation of a mutL homolog in hereditary colon cancer. Papadopoulos et al Science. 1994 Mar 18. 263(5153):1625-9. pCEP9 MLH1 COCA2, FCC2, HNPCC, HNPCC2, hMLH1 Add to Cart
pCMV DCC DCC (Homo sapiens) Mammalian Expression Identification of a chromosome 18q gene that is altered in colorectal cancers. Fearon et al Science. 1990 Jan 5. 247(4938):49-56. pCMV-Neo-XhoI DCC CRC18, CRCR1, IGDCC1, MRMV1 Add to Cart
pCMV DCC mut DCC (Homo sapiens) Mammalian Expression Identification of a chromosome 18q gene that is altered in colorectal cancers. Fearon et al Science. 1990 Jan 5. 247(4938):49-56. pCMV-Neo-XhoI DCC CRC18, CRCR1, IGDCC1, MRMV1 Add to Cart
pCEP4 Bcl-2 Bcl-2 (Homo sapiens) Mammalian Expression Paradoxical inhibition of solid tumor cell growth by bcl2. Pietenpol et al Cancer Res. 1994 Jul 15. 54(14):3714-7. pCEP4 BCL2 Bcl-2, PPP1R50 Add to Cart
p21 promoter A p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
p21 promoter B p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
p21 promoter C p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
p21 promoter D p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
p21 promoter E p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
p21 promoter F p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
p21 promoter G p21 promoter (Homo sapiens) Mammalian Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pJFCAT1 CDKN1A CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 Add to Cart
pCZ45ai p53 binding site (Homo sapiens) Yeast Expression PAK1, a gene that can regulate p53 activity in yeast. Thiagalingam et al Proc Natl Acad Sci U S A. 1995 Jun 20. 92(13):6062-6. pCZ TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pBluescript JTV-1 JTV-1 (Homo sapiens) Bacterial Expression Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. Nicolaides et al Genomics. 1995 Sep 20. 29(2):329-34. pBluescript SK AIMP2 PRO0992, JTV-1, JTV1, P38 Add to Cart
pCMV-Neo-Bam EB-1 EB-1 (Homo sapiens) Mammalian Expression APC binds to the novel protein EB1. Su et al Cancer Res. 1995 Jul 15. 55(14):2972-7. pCMV-Neo-Bam MAPRE1 EB1 Add to Cart
pSG5 PMS2-wt PMS2 (Homo sapiens) Mammalian Expression A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Nicolaides et al Mol Cell Biol. 1998 Mar . 18(3):1635-41. pSG5 PMS2 HNPCC4, PMS2CL, PMSL2 Add to Cart
pSG5 PMS2-134 PMS2 1-134 (Homo sapiens) Mammalian Expression A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Nicolaides et al Mol Cell Biol. 1998 Mar . 18(3):1635-41. pSG5 PMS2 HNPCC4, PMS2CL, PMSL2 Add to Cart
pCRW0.8 p21 (rat) p21 (Rattus norvegicus) Bacterial Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pBluescript SK Cdkn1a Cip1, UV96, Waf1 Add to Cart
pCMW35 p21 (mouse) p21 (Mus musculus) Bacterial Expression Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. el-Deiry et al Cancer Res. 1995 Jul 1. 55(13):2910-9. pBluescript SK Cdkn1a CAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF Add to Cart
pCEP4 p27 p27 (Homo sapiens) Mammalian Expression Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. Pietenpol et al Cancer Res. 1995 Mar 15. 55(6):1206-10. pCEP4 CDKN1B CDKN4, KIP1, MEN1B, MEN4, P27KIP1 Add to Cart
pCEP4 Smad4 Smad4 (Homo sapiens) Mammalian Expression Mad-related genes in the human. Riggins et al Nat Genet. 1996 Jul . 13(3):347-9. pCEP4 SMAD4 DPC4, JIP, MADH4, MYHRS Add to Cart
pCEP4 Smad2 Smad2 (Homo sapiens) Mammalian Expression Mad-related genes in the human. Riggins et al Nat Genet. 1996 Jul . 13(3):347-9. pCEP4 SMAD2 JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 Add to Cart
pSAR-MT Mammalian Expression Apoptosis and APC in colorectal tumorigenesis. Morin et al Proc Natl Acad Sci U S A. 1996 Jul 23. 93(15):7950-4. pSAR-MT Add to Cart
pSAR-MT-beta-gal beta-galactosidase Mammalian Expression Apoptosis and APC in colorectal tumorigenesis. Morin et al Proc Natl Acad Sci U S A. 1996 Jul 23. 93(15):7950-4. pSAR-MT Add to Cart
pSAR-MT-APC APC (Homo sapiens) Mammalian Expression Apoptosis and APC in colorectal tumorigenesis. Morin et al Proc Natl Acad Sci U S A. 1996 Jul 23. 93(15):7950-4. pSAR-MT APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pGST TCF4 DBD TCF4 DNA binding domain (Homo sapiens) Bacterial Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pGEX-2TK TCF7L2 RP11-357H24.1, TCF-4, TCF4 Add to Cart
Pig3 Promoter PIG3 promoter (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pBR322pl-LUC TP53I3 PIG3 Add to Cart
Pig3 Delta Promoter PIG3 promoter (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pBR322pl-LUC TP53I3 PIG3 Add to Cart
pET-SMAD4 Smad4 (Homo sapiens) Bacterial Expression Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel et al Mol Cell. 1998 Mar . 1(4):611-7. pET-33b SMAD4 DPC4, JIP, MADH4, MYHRS Add to Cart
GST-Smad4-MH1 Smad4 (Homo sapiens) Bacterial Expression Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel et al Mol Cell. 1998 Mar . 1(4):611-7. pGEX-2TK SMAD4 DPC4, JIP, MADH4, MYHRS Add to Cart
GST-Smad3-MH1 Smad3 (Homo sapiens) Bacterial Expression Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel et al Mol Cell. 1998 Mar . 1(4):611-7. pGEX-2TK SMAD3 HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 Add to Cart
pCEP4 Pig1 Pig1 (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pCEP4 LGALS7 GAL7, LGALS7A Add to Cart
SBE4-Luc Smad binding element Mammalian Expression, Luciferase Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel et al Mol Cell. 1998 Mar . 1(4):611-7. Luciferase reporter containing four copies of the Smad binding site pBV-Luc Add to Cart
pBK-CMV Pig3 Pig3 (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pBK-CMV TP53I3 PIG3 Add to Cart
pCEP4 Pig4 Pig4 (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pCEP4 SAA1 PIG4, SAA, SAA2, TP53I4 Add to Cart
pCRII Pig5 Pig5 (Homo sapiens) Bacterial Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pCRII ANO9 PIG5, TP53I5, TMEM16J Add to Cart
SBE2-Luc Smad binding element Mammalian Expression, Luciferase Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel et al Mol Cell. 1998 Mar . 1(4):611-7. pGL3 Add to Cart
Vg4-Luc Mad-binding element from Vg Mammalian Expression, Luciferase Human Smad3 and Smad4 are sequence-specific transcription activators. Zawel et al Mol Cell. 1998 Mar . 1(4):611-7. pGL3 Add to Cart
pCRII Pig9 Pig9 (Homo sapiens) Bacterial Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pCRII MAD1L1 MAD1, PIG9, TP53I9, TXBP181 Add to Cart
pBK-CMV Pig10 Pig10 (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pBK-CMV ENC1 CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10 Add to Cart
pBK-CMV Pig11 Pig11 (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pBK-CMV TP53I11 PIG11 Add to Cart
pBK-CMV Pig12 Pig12 (Homo sapiens) Mammalian Expression A model for p53-induced apoptosis. Polyak et al Nature. 1997 Sep 18. 389(6648):300-5. pBK-CMV PTGES MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1 Add to Cart
pCMV-Neo-Bam APC APC (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCMV-Neo-Bam APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pCMV-Neo-Bam APC 1-331 APC (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCMV-Neo-Bam APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pCMV-Neo-Bam APC 1-1309 APC (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCMV-Neo-Bam APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pCMV-Neo-Bam APC 1-1941 APC (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCMV-Neo-Bam APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pCMV-Neo-Bam APC 1-2644 APC (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCMV-Neo-Bam APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pcDNA/Myc TCF4 TCF4 (Homo sapiens) Mammalian Expression Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Korinek et al Science. 1997 Mar 21. 275(5307):1784-7. pcDNA? TCF7L2 RP11-357H24.1, TCF-4, TCF4 Add to Cart
pcDNA/Myc DeltaN TCF4 TCF4 (Homo sapiens) Mammalian Expression Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Korinek et al Science. 1997 Mar 21. 275(5307):1784-7. pcDNA? TCF7L2 RP11-357H24.1, TCF-4, TCF4 Add to Cart
pHR TCF4 TCF4 (Homo sapiens) Mammalian Expression Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Korinek et al Science. 1997 Mar 21. 275(5307):1784-7. pHR TCF7L2 RP11-357H24.1, TCF-4, TCF4 Add to Cart
BDS-2 3x WT (p53 binding site) p53 binding site (Homo sapiens) Mammalian Expression 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11. pBV-Luc SFN YWHAS Add to Cart
BDS-2 3x MUT (p53 binding site) p53 binding site (Homo sapiens) Mammalian Expression 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11. pBV-Luc SFN YWHAS Add to Cart
pBR322 14-3-3 Promoter 14-3-3 promoter (Homo sapiens) Bacterial Expression 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11. pBR322 SFN YWHAS Add to Cart
pCI-neo beta catenin WT beta catenin (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCI-neo CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo Add to Cart
pCI-neo beta catenin S33Y beta catenin (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCI-neo CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo Add to Cart
pCI-neo beta catenin delta45 beta catenin (Homo sapiens) Mammalian Expression Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin et al Science. 1997 Mar 21. 275(5307):1787-90. pCI-neo CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo Add to Cart
CMV-Fast-1 wild-type FAST-1 (Homo sapiens) Mammalian Expression Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pCI-Neo FOXH1 FAST-1, FAST1 Add to Cart
CMV-Fast-1 H83R FAST-1 H83R (Homo sapiens) Mammalian Expression Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pCI-Neo FOXH1 FAST-1, FAST1 Add to Cart
GST-FAST-FL FAST-1 (Homo sapiens) Bacterial Expression Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pGEX-2TK FOXH1 FAST-1, FAST1 Add to Cart
GST-FAST-FH FAST-1 (FH domain) (Homo sapiens) Bacterial Expression Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pGEX-2TK FOXH1 FAST-1, FAST1 Add to Cart
FBE/SBE-Luc FBE/SBE Mammalian Expression, Luciferase Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pBV-Luc Add to Cart
FBE-Luc FAST-1 binding element Mammalian Expression, Luciferase Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pBV-Luc FOXH1 FAST-1, FAST1 Add to Cart
SBE-Luc Smad binding element Mammalian Expression, Luciferase Characterization of human FAST-1, a TGF beta and activin signal transducer. Zhou et al Mol Cell. 1998 Jul . 2(1):121-7. pBV-Luc Add to Cart
pAdTrack-PPARdelta PPAR delta (Homo sapiens) Mammalian Expression, Adenoviral PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pAdTrack-CMV PPARD FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB Add to Cart
mNP-Luc (PPARdelta promoter) PPAR delta promoter NP (Homo sapiens) Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pBV-Luc PPARD FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB Add to Cart
p4xACO-Luc 4xACO Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pBV-Luc Add to Cart
p4xDRE-Luc 4xDRE Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pBV-Luc Add to Cart
p4xTRE1-Luc 4xTRE1 Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pBV-Luc Add to Cart
p4xTRE2-Luc 4xTRE2 Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pBV-Luc Add to Cart
p4xmTRE2-Luc 4xmTRE2 Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pBV-Luc Add to Cart
pBV-Luc Mammalian Expression, Luciferase PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. luciferase reporter plasmid with very low basal activity pBV-Luc Add to Cart
pBI-MCS-EGFP Mammalian Expression Identification and classification of p53-regulated genes. Yu et al Proc Natl Acad Sci U S A. 1999 Dec 7. 96(25):14517-22. pBI-MCS-EGFP Add to Cart
pBI-p53 wt/EGFP p53 (Homo sapiens) Mammalian Expression Identification and classification of p53-regulated genes. Yu et al Proc Natl Acad Sci U S A. 1999 Dec 7. 96(25):14517-22. pBI-MCS-EGFP TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pBI-p53 R175H/EGFP p53 (Homo sapiens) Mammalian Expression Identification and classification of p53-regulated genes. Yu et al Proc Natl Acad Sci U S A. 1999 Dec 7. 96(25):14517-22. pBI-MCS-EGFP TP53 BCC7, LFS1, P53, TRP53 Add to Cart
pBI-p73 wt/EGFP p73 (Homo sapiens) Mammalian Expression Identification and classification of p53-regulated genes. Yu et al Proc Natl Acad Sci U S A. 1999 Dec 7. 96(25):14517-22. pBI-MCS-EGFP TP73 P73 Add to Cart
pGST-RXRalpha RXR alpha (Homo sapiens) Bacterial Expression PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pGEX-2TK RXRA NR2B1 Add to Cart
pGST-PPARdelta PPAR delta (Homo sapiens) Bacterial Expression PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pGEX-2TK PPARD FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB Add to Cart
pGST-PPARgamma PPAR gamma (Homo sapiens) Bacterial Expression PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pGEX-2TK PPARG CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma Add to Cart
pGST-PPARalpha PPAR alpha (Homo sapiens) Bacterial Expression PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. He et al Cell. 1999 Oct 29. 99(3):335-45. pGEX-2TK PPARA SC22CB-5E3.5, NR1C1, PPAR, PPARalpha, hPPAR Add to Cart
14-3-3 KO vector 14-3-3 knockout (Homo sapiens) Bacterial Expression 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Chan et al Nature. 1999 Oct 7. 401(6753):616-20. pBluescript SFN YWHAS Add to Cart
pHRCMV 14-3-3 sigma 14-3-3 sigma (Homo sapiens) Mammalian Expression, Adenoviral 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11. pHRCMV SFN YWHAS Add to Cart
CMV-CDX2-WT CDX2 (Homo sapiens) Mammalian Expression, Adenoviral CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. da et al Oncogene. 1999 Sep 2. 18(35):5010-4. pHRCMV CDX2 CDX-3, CDX3 Add to Cart
CMV-CDX2-MUT CDX2 (Homo sapiens) Mammalian Expression, Adenoviral CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. da et al Oncogene. 1999 Sep 2. 18(35):5010-4. pHRCMV CDX2 CDX-3, CDX3 Add to Cart
deltaMyc-HA c-MYC (Homo sapiens) Mammalian Expression Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. n/a MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
MadMyc-HA MADMYC (Homo sapiens) Mammalian Expression Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. n/a MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pGL3-OT (wt TCF-4 sites) TCF-4 binding sites (Homo sapiens) Mammalian Expression, Luciferase The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Shih et al Cancer Res. 2000 Mar 15. 60(6):1671-6. pGL3-Basic Add to Cart
pGL3-OF (mutant TCF-4 sites) TCF-4 binding sites (Homo sapiens) Mammalian Expression, Luciferase The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Shih et al Cancer Res. 2000 Mar 15. 60(6):1671-6. pGL3-Basic Add to Cart
pGEX TEM-1 TEM1 (Homo sapiens) Bacterial Expression Cell surface tumor endothelial markers are conserved in mice and humans. Carson-Walter et al Cancer Res. 2001 Sep 15. 61(18):6649-55. pGEX-2TK CD248 TEM1, CD164L1, MGC119478, MGC119479 Add to Cart
pIVEX2.3 TEM-7 TEM7 (Homo sapiens) Bacterial Expression Cell surface tumor endothelial markers are conserved in mice and humans. Carson-Walter et al Cancer Res. 2001 Sep 15. 61(18):6649-55. pIVEX2.3-MCS Add to Cart
pIVEX2.3 TEM-8 TEM8 (Homo sapiens) Bacterial Expression Cell surface tumor endothelial markers are conserved in mice and humans. Carson-Walter et al Cancer Res. 2001 Sep 15. 61(18):6649-55. pIVEX2.3-MCS Add to Cart
pBV-Luc wt MBS1-4 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBV-Luc mut MBS1-4 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBV-Luc mut MBS1 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBV-Luc mut MBS2 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBV-Luc mut MBS1-3 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBV-Luc mut MBS3+4 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBV-Luc mut MBS4 c-MYC binding sites (Homo sapiens) Mammalian Expression, Luciferase Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pBR322 hCDK4 promoter CDK4 promoter (Homo sapiens) Bacterial Expression Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBR322 CDK4 CMM3, PSK-J3 Add to Cart
pBR322 mCDK4 promoter CDK4 promoter (Mus musculus) Bacterial Expression Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. pBR322 Cdk4 Crk3 Add to Cart
G1BgSVNA-CDK4 CDK4 (Homo sapiens) Mammalian Expression, Retroviral Identification of CDK4 as a target of c-MYC. Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. G1BgSVNA CDK4 CMM3, PSK-J3 Add to Cart
pCI-neo-hCG Beta-hCG (Homo sapiens) Mammalian Expression Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropin. Shih et al Nat Med. 2000 Jun . 6(6):711-4. pCI-neo CGB CGB3, CGB5, CGB7, CGB8, hCGB Add to Cart
BAX KO vector BAX knockout (Homo sapiens) Bacterial Expression Role of BAX in the apoptotic response to anticancer agents. Zhang et al Science. 2000 Nov 3. 290(5493):989-92. pBluescript II SK BAX BCL2L4 Add to Cart
Ad-CBR (GFP/cAPC) cAPC (Homo sapiens) Mammalian Expression, Adenoviral The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Shih et al Cancer Res. 2000 Mar 15. 60(6):1671-6. pShuttle / pAdTrack ? APC BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 Add to Cart
pFredA Mammalian Expression Securin is required for chromosomal stability in human cells. Jallepalli et al Cell. 2001 May 18. 105(4):445-57. pFredA Add to Cart
pFredB Mammalian Expression Securin is required for chromosomal stability in human cells. Jallepalli et al Cell. 2001 May 18. 105(4):445-57. pFredB Add to Cart
pFredA-PTTG1 PTTG1 (Homo sapiens) Mammalian Expression Securin is required for chromosomal stability in human cells. Jallepalli et al Cell. 2001 May 18. 105(4):445-57. pFredA PTTG1 EAP1, HPTTG, PTTG, TUTR1 Add to Cart
pFredB-PTTG1 PTTG1 (Homo sapiens) Mammalian Expression Securin is required for chromosomal stability in human cells. Jallepalli et al Cell. 2001 May 18. 105(4):445-57. pFredB PTTG1 EAP1, HPTTG, PTTG, TUTR1 Add to Cart
pHAHA Mammalian Expression PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pCEP4 Add to Cart
pCEP4-HA-BAX BAX alpha (Homo sapiens) Mammalian Expression PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pCEP4 BAX BCL2L4 Add to Cart
pHA-PUMA PUMA (Homo sapiens) Mammalian Expression PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pCEP4 BBC3 JFY-1, JFY1, PUMA Add to Cart
pHA-PUMA DeltaBH3 PUMA (Homo sapiens) Mammalian Expression PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pCEP4 BBC3 JFY-1, JFY1, PUMA Add to Cart
pBI-EGFP-PUMA PUMA (Homo sapiens) Mammalian Expression PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pBI-MCS-EGFP BBC3 JFY-1, JFY1, PUMA Add to Cart
PUMA Frag1-Luc PUMA promotor fragment (Homo sapiens) Mammalian Expression, Luciferase PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pBV-Luc BBC3 JFY-1, JFY1, PUMA Add to Cart
PUMA Frag2-Luc PUMA promotor fragment (Homo sapiens) Mammalian Expression, Luciferase PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pBV-Luc BBC3 JFY-1, JFY1, PUMA Add to Cart
4XBS2WT-Luc p53 binding sites (Homo sapiens) Mammalian Expression, Luciferase PUMA induces the rapid apoptosis of colorectal cancer cells. Yu et al Mol Cell. 2001 Mar . 7(3):673-82. pBV-Luc Add to Cart
c-myc promoter (TBE 1/2 - wt) c-myc promoter (TBE 1/2 wt) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (TBE 1m/2m - mut) c-myc promoter (TBE 1m/2m mut) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (4x TBE1 - wt) c-myc promoter (4xTBE1 wt) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (4x TBE1 - mut) c-myc promoter (4xTBE1 mut) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (4x TBE2 - wt) c-myc promoter (4xTBE2 wt) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (4x TBE2 - mut) c-myc promoter (4xTBE2 mut) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Del 1) c-myc promoter (Del 1) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Del 2) c-myc promoter (Del 2) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Del 3) c-myc promoter (Del 3) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Del 4) c-myc promoter (Del 4) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Frag A) c-myc promoter (Frag A) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Frag B) c-myc promoter (Frag B) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Frag C) c-myc promoter (Frag C) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Frag D) c-myc promoter (Frag D) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
c-myc promoter (Frag E) c-myc promoter (Frag E) (Homo sapiens) Mammalian Expression, Luciferase Identification of c-MYC as a target of the APC pathway. He et al Science. 1998 Sep 4. 281(5382):1509-12. pBV-Luc MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
pTRE-FDXR wt FDXR (Homo sapiens) Mammalian Expression Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Hwang et al Nat Med. 2001 Oct . 7(10):1111-7. pTRE FDXR ADXR Add to Cart
pTRE-FDXR mut FDXR (Homo sapiens) Mammalian Expression Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Hwang et al Nat Med. 2001 Oct . 7(10):1111-7. pTRE FDXR ADXR Add to Cart
pBI-EGFP-MnSOD MnSOD (Homo sapiens) Mammalian Expression Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Hwang et al Nat Med. 2001 Oct . 7(10):1111-7. pBI-EGFP2 SOD2 RP1-56L9.2, IPOB, MNSOD, MVCD6 Add to Cart
FDXR KO-1 FDXR knockout (Homo sapiens) Bacterial Expression Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Hwang et al Nat Med. 2001 Oct . 7(10):1111-7. pBluescript II KS FDXR ADXR Add to Cart
FDXR KO-2A FDXR knockout (Homo sapiens) Mammalian Expression Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Hwang et al Nat Med. 2001 Oct . 7(10):1111-7. pFredA FDXR ADXR Add to Cart
IRES-puro-GFP GFP Mammalian Expression Use of isogenic human cancer cells for high-throughput screening and drug discovery. Torrance et al Nat Biotechnol. 2001 Oct . 19(10):940-5. pIRESpuro2 Add to Cart
pCEP4-PRL-3 PRL-3 (Homo sapiens) Mammalian Expression A phosphatase associated with metastasis of colorectal cancer. Saha et al Science. 2001 Nov 9. 294(5545):1343-6. pCEP4 PTP4A3 PRL-3, PRL-R, PRL3 Add to Cart
PPARdelta KO vector PPAR delta (Homo sapiens) Bacterial Expression Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Park et al Proc Natl Acad Sci U S A. 2001 Feb 27. 98(5):2598-603. pBluescript II KS PPARD FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB Add to Cart
pTBRII / CEP-Zeo / Hygro TGF beta type II receptor (Homo sapiens) Mammalian Expression Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. Zhou et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2412-6. pCEP4 TGFBR2 AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII Add to Cart
pBI-GFP Mammalian Expression Mutations of mitotic checkpoint genes in human cancers. Cahill et al Nature. 1998 Mar 19. 392(6673):300-3. pBI-GFP Add to Cart
pBI-GFP-Bub1-wt BUB1 (Homo sapiens) Mammalian Expression Mutations of mitotic checkpoint genes in human cancers. Cahill et al Nature. 1998 Mar 19. 392(6673):300-3. pBI-GFP BUB1 BUB1A, BUB1L, hBUB1 Add to Cart
pBI-GFP-Bub1-S492Y BUB1 S492Y (Homo sapiens) Mammalian Expression Mutations of mitotic checkpoint genes in human cancers. Cahill et al Nature. 1998 Mar 19. 392(6673):300-3. pBI-GFP BUB1 BUB1A, BUB1L, hBUB1 Add to Cart
pBI-GFP-Bub1-deletion mutant BUB1 deletion mutant (Homo sapiens) Mammalian Expression Mutations of mitotic checkpoint genes in human cancers. Cahill et al Nature. 1998 Mar 19. 392(6673):300-3. pBI-GFP BUB1 BUB1A, BUB1L, hBUB1 Add to Cart
pCAR-OF reporter CAR-OF Mammalian Expression A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Nicolaides et al Mol Cell Biol. 1998 Mar . 18(3):1635-41. pCEP4 Add to Cart
pCAR-IF reporter CAR-IF Mammalian Expression A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Nicolaides et al Mol Cell Biol. 1998 Mar . 18(3):1635-41. pCEP4 Add to Cart
pCI-Neo-PTPRT (R632X) PTPRT R632X (Homo sapiens) Mammalian Expression Mutational analysis of the tyrosine phosphatome in colorectal cancers. Wang et al Science. 2004 May 21. 304(5674):1164-6. pCI-Neo PTPRT RP5-1121H13.2, RPTPrho Add to Cart
pCI-Neo-PTPRT (WT) PTPRT (Homo sapiens) Mammalian Expression Mutational analysis of the tyrosine phosphatome in colorectal cancers. Wang et al Science. 2004 May 21. 304(5674):1164-6. pCI-Neo PTPRT RP5-1121H13.2, RPTPrho Add to Cart
PIK3CA - Exon20 H1047R PIK3CA H1047R (Homo sapiens) Mammalian Expression High frequency of mutations of the PIK3CA gene in human cancers. Samuels et al Science. 2004 Apr 23. 304(5670):554. pCMV2-Tag 2A PIK3CA CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha Add to Cart
PIK3CA - Exon20 E545K (pFastBac) PIK3CA E545K (Homo sapiens) Mammalian Expression ; Baculoviral High frequency of mutations of the PIK3CA gene in human cancers. Samuels et al Science. 2004 Apr 23. 304(5670):554. pFastBac HT PIK3CA CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha Add to Cart
PIK3CA - Exon9 H1047R (pFastBac) PIK3CA H1047R (Homo sapiens) Mammalian Expression ; Baculoviral High frequency of mutations of the PIK3CA gene in human cancers. Samuels et al Science. 2004 Apr 23. 304(5670):554. pFastBac HT PIK3CA CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha Add to Cart
PIK3CA - Exon9 E545K PIK3CA E545K (Homo sapiens) Mammalian Expression High frequency of mutations of the PIK3CA gene in human cancers. Samuels et al Science. 2004 Apr 23. 304(5670):554. pCMV2-Tag 2A PIK3CA CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha Add to Cart
PIK3CA-WT PIK3CA (Homo sapiens) Mammalian Expression High frequency of mutations of the PIK3CA gene in human cancers. Samuels et al Science. 2004 Apr 23. 304(5670):554. pCMV2-Tag 2A PIK3CA CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha Add to Cart
PIK3CA-WT (pFastBac) PIK3CA (Homo sapiens) Mammalian Expression ; Baculoviral High frequency of mutations of the PIK3CA gene in human cancers. Samuels et al Science. 2004 Apr 23. 304(5670):554. pFastBac HT PIK3CA CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha Add to Cart
SMAD4 KO Hyg Smad4 knock-out construct (Homo sapiens) Bacterial Expression DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Zawel et al Proc Natl Acad Sci U S A. 2002 Mar 5. 99(5):2848-53. pBluescript II SK SMAD4 DPC4, JIP, MADH4, MYHRS Add to Cart
SMAD4 KO Neo Smad4 knock-out construct (Homo sapiens) Bacterial Expression DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Zawel et al Proc Natl Acad Sci U S A. 2002 Mar 5. 99(5):2848-53. pBluescript II SK SMAD4 DPC4, JIP, MADH4, MYHRS Add to Cart
DNMT1 KO Hyg DNMT1 knock-out construct (Homo sapiens) Bacterial Expression DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee et al Nature. 2002 Apr 4. 416(6880):552-6. pSL301 DNMT1 ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT Add to Cart
DNMT1 KO Neo DNMT1 knock-out construct (Homo sapiens) Bacterial Expression DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee et al Nature. 2002 Apr 4. 416(6880):552-6. pSL301 DNMT1 ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT Add to Cart
DNMT3b KO Hyg DNMT3b knock-out construct (Homo sapiens) Bacterial Expression DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee et al Nature. 2002 Apr 4. 416(6880):552-6. pSL301 DNMT3B RP5-1085F17.2, ICF, ICF1, M.HsaIIIB Add to Cart
DNMT3b KO Neo DNMT3b knock-out construct (Homo sapiens) Bacterial Expression DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee et al Nature. 2002 Apr 4. 416(6880):552-6. pSL301 DNMT3B RP5-1085F17.2, ICF, ICF1, M.HsaIIIB Add to Cart
pCMV-Myc CDC4 WT* CDC4 (Homo sapiens) Mammalian Expression Inactivation of hCDC4 can cause chromosomal instability. Rajagopalan et al Nature. 2004 Mar 4. 428(6978):77-81. pCMV-Myc FBXW7 AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4 Add to Cart
pCMV-Myc CDC4 R465C CDC4 R465C (Homo sapiens) Mammalian Expression Inactivation of hCDC4 can cause chromosomal instability. Rajagopalan et al Nature. 2004 Mar 4. 428(6978):77-81. pCMV-Myc FBXW7 AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4 Add to Cart
Cyclin E-pBI-EGFP Cyclin E (Homo sapiens) Mammalian Expression Inactivation of hCDC4 can cause chromosomal instability. Rajagopalan et al Nature. 2004 Mar 4. 428(6978):77-81. pBI-EGFP CCNE1 CCNE Add to Cart
pCI-neo Flag HAUSP HAUSP (Homo sapiens) Mammalian Expression HAUSP is required for p53 destabilization. Cummins et al Cell Cycle. 2004 Jun . 3(6):689-92. pCI-Neo USP7 HAUSP, TEF1 Add to Cart
DICER KO vector Dicer knock-out (Homo sapiens) Mammalian Expression ; adeno-associated viral The colorectal microRNAome. Cummins et al Proc Natl Acad Sci U S A. 2006 Mar 7. 103(10):3687-92. pBluescript DICER1 DCR1, Dicer, Dicer1e, HERNA, MNG1, RMSE2 Add to Cart
LIP-WT Liposomase Bacterial Expression A bacterial protein enhances the release and efficacy of liposomal cancer drugs. Cheong et al Science. 2006 Nov 24. 314(5803):1308-11. pCR2.1 / T7-GFP Add to Cart
RS314-SN Gal1-p53 (Homo sapiens) Yeast Expression PAK1, a gene that can regulate p53 activity in yeast. Thiagalingam et al Proc Natl Acad Sci U S A. 1995 Jun 20. 92(13):6062-6. pRS314 TP53 BCC7, LFS1, P53, TRP53 Add to Cart
RS314-H Gal1-p53 (Homo sapiens) Yeast Expression PAK1, a gene that can regulate p53 activity in yeast. Thiagalingam et al Proc Natl Acad Sci U S A. 1995 Jun 20. 92(13):6062-6. pRS314 TP53 BCC7, LFS1, P53, TRP53 Add to Cart
RS314 Yeast Expression PAK1, a gene that can regulate p53 activity in yeast. Thiagalingam et al Proc Natl Acad Sci U S A. 1995 Jun 20. 92(13):6062-6. pRS314 Add to Cart
pFastBac1 PIK3R1 PIK3R1 (Homo sapiens) Insect Expression Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Samuels et al Cancer Cell. 2005 Jun . 7(6):561-73. pFastBac1 PIK3R1 AGM7, GRB1, IMD36, p85, p85-ALPHA Add to Cart
pFastBac1 PIK3R1-Ni PIK3R1-Ni (Homo sapiens) Insect Expression Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Samuels et al Cancer Cell. 2005 Jun . 7(6):561-73. pFastBac1 PIK3R1 AGM7, GRB1, IMD36, p85, p85-ALPHA Add to Cart
pRS314-MDM2 MDM2 (Homo sapiens) Yeast Expression Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53. Oliner et al Nature. 1993 Apr 29. 362(6423):857-60. pRS314 w/Gal1 MDM2 ACTFS, HDMX, hdm2 Add to Cart