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Bob Weinberg Lab Plasmids


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Title Authors Publication
Rb-plasmids (unpublished)
pBABE-vectors (unpublished)
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA Cell 2001 Oct 19;107(2):149-59.
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8.
Inhibition of telomerase limits the growth of human cancer cells. Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA Nat Med 1999 Oct;5(10):1164-70.
Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, DeCaprio JA, Weinberg RA Mol Cell Biol 2002 Apr;22(7):2111-23.
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA Cell 1997 Aug 22;90(4):785-95.
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA Cell 2004 Jun 25;117(7):927-39.
Lentivirus-delivered stable gene silencing by RNAi in primary cells. Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD RNA 2003 Apr;9(4):493-501.
Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Geng Y, Eaton EN, Picon M, Roberts JM, Lundberg AS, Gifford A, Sardet C, Weinberg RA Oncogene 1996 Mar 21;12(6):1173-80.
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA Cell. 1992 Sep 18. 70(6):993-1006.
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Gupta PB, Kuperwasser C, Brunet JP, Ramaswamy S, Kuo WL, Gray JW, Naber SP, Weinberg RA Nat Genet. 2005 Oct . 37(10):1047-54.
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA Proc Natl Acad Sci U S A. 1999 Oct 26. 96(22):12442-7.
Expression cloning and characterization of the TGF-beta type III receptor. Wang XF, Lin HY, Ng-Eaton E, Downward J, Lodish HF, Weinberg RA Cell. 1991 Nov 15. 67(4):797-805.
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, Chen A, Weinberg RA Proc Natl Acad Sci U S A. 1995 Mar 14. 92(6):2403-7.
Growth suppression by p16ink4 requires functional retinoblastoma protein. Medema RH, Herrera RE, Lam F, Weinberg RA Proc Natl Acad Sci U S A. 1995 Jul 3. 92(14):6289-93.
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Bargmann CI, Hung MC, Weinberg RA Cell. 1986 Jun 6. 45(5):649-57.
Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Liu X, Sun Y, Constantinescu SN, Karam E, Weinberg RA, Lodish HF Proc Natl Acad Sci U S A. 1997 Sep 30. 94(20):10669-74.
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA Cell. 2005 May 6. 121(3):335-48.
Species- and cell type-specific requirements for cellular transformation. Rangarajan A, Hong SJ, Gifford A, Weinberg RA Cancer Cell. 2004 Aug . 6(2):171-83.
The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA Proc Natl Acad Sci U S A. 2006 Dec 12. 103(50):18969-74.
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Mani SA, Yang J, Brooks M, Schwaninger G, Zhou A, Miura N, Kutok JL, Hartwell K, Richardson AL, Weinberg RA Proc Natl Acad Sci U S A. 2007 Jun 12. 104(24):10069-74.
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Ma L, Teruya-Feldstein J, Weinberg RA Nature. 2007 Oct 11. 449(7163):682-8.
The epithelial-mesenchymal transition generates cells with properties of stem cells. Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA Cell. 2008 May 16. 133(4):704-15.
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA Cancer Res. 2008 May 15. 68(10):3645-54.
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA Cell. 2008 Jul 11. 134(1):62-73.
Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Rai P, Onder TT, Young JJ, McFaline JL, Pang B, Dedon PC, Weinberg RA Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74.
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szasz AM, Wang ZC, Brock JE, Richardson AL, Weinberg RA Cell. 2009 Jun 12. 137(6):1032-46.
empty vector (unpublished)
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, Teruya-Feldstein J, Reinhardt F, Onder TT, Valastyan S, Westermann F, Speleman F, Vandesompele J, Weinberg RA Nat Cell Biol. 2010 Mar . 12(3):247-56.
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, Teruya-Feldstein J, Bell GW, Weinberg RA Nat Biotechnol. 2010 Apr . 28(4):341-7.
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA Nature. 1993 May 6. 363(6424):45-51.
Slug and Sox9 cooperatively determine the mammary stem cell state. Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zurrer-Hardi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA Cell. 2012 Mar 2;148(5):1015-28.
Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Shibue T, Weinberg RA Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5.
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Morgenstern JP, Land H Nucleic Acids Res. 1990 Jun 25;18(12):3587-96.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
1761PBSK HRbchuman Rb (Homo sapiens)Bacterial Expression Rb-plasmids (unpublished) pBSK+ RB1 OSRC, PPP1R130, RB, p105-Rb, pRb, pp110 Add to Cart
1763RcCMV/Rbhuman Rb (Homo sapiens)Mammalian Expression Rb-plasmids (unpublished) Rc/CMV RB1 OSRC, PPP1R130, RB, p105-Rb, pRb, pp110 Add to Cart
1764pBABE-puroMammalian Expression, RetroviralAdvanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990 Jun 25;18(12):3587-96. Retroviral vector for cloning and expressing your gene of interest. Puromycin selection. pBABE-puro Add to Cart
1765pBABE-hygroMammalian Expression, RetroviralAdvanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990 Jun 25;18(12):3587-96. Retroviral vector for cloning and expressing your gene of interest. Hygromycin selection. pBABE-hygro Add to Cart
1766pBABE-zeo (pBABE-bleo)Mammalian Expression, RetroviralAdvanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990 Jun 25;18(12):3587-96. Retroviral vector for cloning and expressing your gene of interest. Zeocin selection. pBABE-zeo Add to Cart
1767pBABE-neoMammalian Expression, RetroviralAdvanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990 Jun 25;18(12):3587-96. Retroviral vector for cloning and expressing your gene of interest. Neomycin selection. pBABE-neo Add to Cart
1768pBabe-puro Ras V12ras V12 (Homo sapiens)Mammalian Expression, Retroviral pBABE-vectors (unpublished) pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
1769pYESir2-puroSir2 (Homo sapiens)Mammalian Expression, RetroviralhSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001 Oct 19;107(2):149-59. pBABE-puro SIRT1 SIR2, SIR2L1, SIR2alpha Add to Cart
1770pYESir2HY-puroSir2 (Homo sapiens)Mammalian Expression, RetroviralhSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001 Oct 19;107(2):149-59. pBABE-puro SIRT1 SIR2, SIR2L1, SIR2alpha Add to Cart
1771pBABE-puro-hTERThTERT (Homo sapiens)Mammalian Expression, RetroviralDissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. Retroviral expression of hTERT. Used to create immortalized cell lines. pBABE-puro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1772pBABE-puro-hTERT-HAhTERT (Homo sapiens)Mammalian Expression, RetroviralDissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. pBABE-puro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1773pBABE-hygro-hTERThTERT (Homo sapiens)Mammalian Expression, RetroviralDissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. Retroviral expression of hTERT. Used to create immortalized cell lines. pBABE-hygro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1774pBABE-neo-hTERThTERT (Homo sapiens)Mammalian Expression, RetroviralDissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. Retroviral expression of hTERT. Used to create immortalized cell lines. pBABE-neo TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1775pBABE-puro-DN-hTERThTERT (Homo sapiens)Mammalian Expression, RetroviralInhibition of telomerase limits the growth of human cancer cells. Nat Med 1999 Oct;5(10):1164-70. pBABE-puro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1778pBABE-zeo largeTgenomiclarge T and small T antigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp6 SV40gp6 Add to Cart
1779pBABE-zeo largeTcDNAlarge T antigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp6 SV40gp6 Add to Cart
1780pBABE-neo largeTcDNAlarge T antigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. Retroviral expression of Large T Antigen. Used to create immortalized cell lines. pBABE-neo SV40gp6 SV40gp6 Add to Cart
1781pCI neo-hEST2hTERT (Homo sapiens)Mammalian ExpressionhEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 1997 Aug 22;90(4):785-95. pCI neo TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1782pCI neo-hEST2-HAhTERT (Homo sapiens)Mammalian ExpressionhEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 1997 Aug 22;90(4):785-95. pCI neo TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
1783pBABE-puro-mTwistTwist (Mus musculus)Mammalian Expression, RetroviralTwist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004 Jun 25;117(7):927-39. pBABE-puro Twist1 M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt Add to Cart
1784Twist-siRNA3siTwist (Mus musculus)Mammalian ExpressionTwist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004 Jun 25;117(7):927-39. pSP-108 Twist1 M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt Add to Cart
8449pUMVCMammalian Expression, RetroviralLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. Packaging plasmid for producing MuLV retroviral particles. Use in conjunction with an envelope plasmid such as pCMV-VSV-G. pUMVC Add to Cart
8450RetrohairMammalian Expression, Retroviral, RNAiLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. pBABE Add to Cart
8451Lentihair s1GFPsiRNA against GFPMammalian Expression, Lentiviral, RNAiLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. pLentihair Add to Cart
8452pMKO.1 puroMammalian Expression, Retroviral, RNAiLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. pMSCV Add to Cart
8453pLKO.1 puroMammalian Expression, Lentiviral, RNAiLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. 3rd gen lentiviral backbone for cloning and expression of new shRNA sequences. Uses puromycin for selection. pLKO.1 Add to Cart
8454pCMV-VSV-GMammalian ExpressionLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. Envelope protein for producing lentiviral and MuLV retroviral particles. Use in conjunction with a packaging vector such as pCMV-dR8.2 dvpr (lentiviral) or pUMVC (MuLV retroviral). na Add to Cart
8455pCMV-dR8.2 dvprMammalian Expression, LentiviralLentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003 Apr;9(4):493-501. 2nd generation lentiviral packaging plasmid. Can be used with 2nd and 3rd generation transfer vectors. Use in conjunction with an envelope plasmid such as pCMV-VSV-G. na Add to Cart
8456Twist-siRNA5siTwist (Mus musculus)Mammalian ExpressionTwist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004 Jun 25;117(7):927-39. pSP-108 Twist1 M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt Add to Cart
8457Twist-siRNA7siTwist (Mus musculus)Mammalian ExpressionTwist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004 Jun 25;117(7):927-39. pSP-108 Twist1 M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt Add to Cart
845810-4 cyclin E promoterhuman cyclin E promoter (Homo sapiens)Mammalian Expression, LuciferaseRegulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 1996 Mar 21;12(6):1173-80. pGL-2 CCNE1 CCNE, pCCNE1 Add to Cart
8460EE-mut SV40 luchuman cyclin E promoter fragment, mutant (Homo sapiens)Mammalian Expression, LuciferaseRegulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 1996 Mar 21;12(6):1173-80. pGL2-Promoter CCNE1 CCNE, pCCNE1 Add to Cart
8581pBABE-neo largeTcDNA K1large T antigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-neo SV40gp6 SV40gp6 Add to Cart
8582pBABE-neo largeTcDNA delta434-444large T antigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-neo SV40gp6 SV40gp6 Add to Cart
8583pBABE-zeo smallTSV40 small T AntigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7 Add to Cart
8959Rc/CMV cyclin Acyclin A (Homo sapiens)Mammalian ExpressionRegulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNA2 CCN1, CCNA Add to Cart
8961Rc/CMV cyclin Ccyclin C (Homo sapiens)Mammalian ExpressionRegulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNC CycC Add to Cart
8962Rc/CMV cyclin D1cyclin D1 (Homo sapiens)Mammalian ExpressionRegulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCND1 BCL1, D11S287E, PRAD1, U21B31 Add to Cart
8963Rc/CMV cyclin Ecyclin E (Homo sapiens)Mammalian ExpressionRegulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNE1 CCNE, pCCNE1 Add to Cart
9048pBABE-neo largeTcDNA H42Qlarge T antigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-neo SV40gp6 SV40gp6 Add to Cart
9058pBABE-hygro p53 DDp53 DD (Mus musculus)Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE hygro Trp53 Tp53, bbl, bfy, bhy, p44, p53 Add to Cart
9059pMIG small TSV40 small T AntigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7 Add to Cart
9060pMIG small T C97S E102QSV40 small T Antigen 97, 102Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7 Add to Cart
9061pMIG small T 110SV40 small T Antigen 110Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7 Add to Cart
9062pMIG small T H42QSV40 small T Antigen H42QMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7 Add to Cart
9063pBABE-zeo small T 110SV40 small T Antigen 110Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7 Add to Cart
9064pBABE-zeo small T C97S E102QSV40 small T Antigen 97, 102Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7 Add to Cart
9065pBABE-zeo small T H42QSV40 small T AntigenMammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7 Add to Cart
10690pBABE-zeo small T 88SV40 small T Antigen 88Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7 Add to Cart
10691pMIG small T 88SV40 small T Antigen 88Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7 Add to Cart
10900GFP-siRNA controlsiGFPMammalian ExpressionTwist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004 Jun 25;117(7):927-39. pSP-108 Add to Cart
10901pBABE-puro HGFHGF (Homo sapiens)Mammalian Expression, RetroviralThe melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005 Oct . 37(10):1047-54. pBABE-puro HGF DFNB39, F-TCF, HGFB, HPTA, SF Add to Cart
10902pBABE-puro TPR-MetTPR-Met (Homo sapiens)Mammalian Expression, RetroviralThe melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005 Oct . 37(10):1047-54. pBABE-puro MET AUTS9, DFNB97, HGFR, RCCP2, c-Met TPR Add to Cart
10903siSlug1siSlug (Homo sapiens)Mammalian Expression, Lentiviral, RNAiThe melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005 Oct . 37(10):1047-54. pLKO.1 SNAI2 SLUG, SLUGH1, SNAIL2, WS2D Add to Cart
10904siSlug2siSlug (Homo sapiens)Mammalian Expression, Lentiviral, RNAiThe melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005 Oct . 37(10):1047-54. pLKO.1 SNAI2 SLUG, SLUGH1, SNAIL2, WS2D Add to Cart
10905siSlug3siSlug (Homo sapiens)Mammalian Expression, Lentiviral, RNAiThe melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005 Oct . 37(10):1047-54. pLKO.1 SNAI2 SLUG, SLUGH1, SNAIL2, WS2D Add to Cart
10908pCI-Neo HA-hSnoNSnoN (Homo sapiens)Mammalian ExpressionSnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Proc Natl Acad Sci U S A. 1999 Oct 26. 96(22):12442-7. pCI-neo SKIL SNO, SnoA, SnoI, SnoN Add to Cart
10910pCI-Neo HA-hSkiSki (Homo sapiens)Mammalian ExpressionSnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Proc Natl Acad Sci U S A. 1999 Oct 26. 96(22):12442-7. pCI-neo SKI SGS, SKV Add to Cart
10911Rc/CMV cyclin B2cyclin B2 (Homo sapiens)Mammalian ExpressionRegulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNB2 HsT17299 Add to Cart
10912Rc/CMV cyclin D3cyclin D3 (Homo sapiens)Mammalian ExpressionRegulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCND3 Add to Cart
10913pcDNA type III TGF beta receptor (R3-OFF)R3-OFF (Rattus norvegicus)Mammalian ExpressionExpression cloning and characterization of the TGF-beta type III receptor. Cell. 1991 Nov 15. 67(4):797-805. pcDNAI neo Tgfbr3 betaglycan Add to Cart
10914pcDNA3-E2F4E2F4 (Homo sapiens)Mammalian ExpressionE2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc Natl Acad Sci U S A. 1995 Mar 14. 92(6):2403-7. pcDNA3 E2F4 E2F-4 Add to Cart
10916pCMV p16 INK4Ap16 INK4 (Homo sapiens)Mammalian ExpressionGrowth suppression by p16ink4 requires functional retinoblastoma protein. Proc Natl Acad Sci U S A. 1995 Jul 3. 92(14):6289-93. pcDNA3 CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 Add to Cart
10917pSV2 neuNneuN (Rattus norvegicus)Mammalian ExpressionMultiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell. 1986 Jun 6. 45(5):649-57. pSV2 neo Erbb2 Add to Cart
10918pSV2 neuNTneuNT (Rattus norvegicus)Mammalian ExpressionMultiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell. 1986 Jun 6. 45(5):649-57. pSV2 neo Erbb2 Add to Cart
10919pSV2 neuTneuT (Rattus norvegicus)Mammalian ExpressionMultiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell. 1986 Jun 6. 45(5):649-57. pSV2-dhfr Erbb2 Add to Cart
10920pEXL flag Smad3Smad3 (Homo sapiens)Mammalian ExpressionTransforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc Natl Acad Sci U S A. 1997 Sep 30. 94(20):10669-74. pEXL (derived from pEGFP-N1) SMAD3 HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 Add to Cart
11254pBABE-hygro CDK4 R24CCDK4 (Homo sapiens)Mammalian Expression, RetroviralEnumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-hygro CDK4 CMM3, PSK-J3 Add to Cart
12269pWZL Blast GFPEGFPMammalian Expression, RetroviralStromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005 May 6. 121(3):335-48. pWZL Blast Add to Cart
12270pBABE puro SDF-1 alphaSDF-1 alpha (Homo sapiens)Mammalian Expression, RetroviralStromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005 May 6. 121(3):335-48. pBABE-puro CXCL12 IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1 Add to Cart
12271pLKO.1 puro CXCR4 siRNA-1CXCR4 siRNA (Homo sapiens)Mammalian Expression, Lentiviral, RNAiStromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005 May 6. 121(3):335-48. pLKO.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
12272pLKO.1 puro CXCR4 siRNA-2CXCR4 siRNA (Homo sapiens)Mammalian Expression, Lentiviral, RNAiStromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005 May 6. 121(3):335-48. pLKO.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
12273pLKO.1 puro GFP siRNAGFP siRNAMammalian Expression, Lentiviral, RNAiStromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005 May 6. 121(3):335-48. pLKO.1 Add to Cart
12274pBabe puro H-Ras G12V T35SH-Ras G12V T35S (Homo sapiens)Mammalian Expression, RetroviralSpecies- and cell type-specific requirements for cellular transformation. Cancer Cell. 2004 Aug . 6(2):171-83. pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
12275pBabe puro H-Ras G12V E37GH-Ras G12V E37G (Homo sapiens)Mammalian Expression, RetroviralSpecies- and cell type-specific requirements for cellular transformation. Cancer Cell. 2004 Aug . 6(2):171-83. pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
12276pBabe puro H-Ras G12V Y40CH-Ras G12V Y40C (Homo sapiens)Mammalian Expression, RetroviralSpecies- and cell type-specific requirements for cellular transformation. Cancer Cell. 2004 Aug . 6(2):171-83. pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
12277pWZL Blast H-Ras G12V E37GH-Ras G12V E37G (Homo sapiens)Mammalian Expression, RetroviralSpecies- and cell type-specific requirements for cellular transformation. Cancer Cell. 2004 Aug . 6(2):171-83. pWZL Blast HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
12278pWZL Blast H-Ras G12V T35SH-Ras G12V T35S (Homo sapiens)Mammalian Expression, RetroviralSpecies- and cell type-specific requirements for cellular transformation. Cancer Cell. 2004 Aug . 6(2):171-83. pWZL Blast HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
12279pWZL Blast H-Ras G12V Y40CH-Ras G12V Y40C (Homo sapiens)Mammalian Expression, RetroviralSpecies- and cell type-specific requirements for cellular transformation. Cancer Cell. 2004 Aug . 6(2):171-83. pWZL Blast HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras Add to Cart
14095pWZL blast goosecoidgoosecoid (Mus musculus)Mammalian Expression, RetroviralThe Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proc Natl Acad Sci U S A. 2006 Dec 12. 103(50):18969-74. pWZL Blast Gsc Add to Cart
14096pWZL blast HA goosecoidgoosecoid (Mus musculus)Mammalian Expression, RetroviralThe Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proc Natl Acad Sci U S A. 2006 Dec 12. 103(50):18969-74. pWZL Blast Gsc Add to Cart
15535pBabe human FOXC2FOXC2 (Homo sapiens)Mammalian Expression, RetroviralMesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci U S A. 2007 Jun 12. 104(24):10069-74. pBabe puro FOXC2 FKHL14, LD, MFH-1, MFH1 Add to Cart
16070MDH1-PGK-GFP microRNA-10bmicroRNA-10b (Homo sapiens)Mammalian Expression, Retroviral, RNAiTumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature. 2007 Oct 11. 449(7163):682-8. MDH1-PGK-GFP 2.0 MIR10B MIRN10B, hsa-mir-10b, miRNA10B, mir-10b Add to Cart
18798pWZL Blast Snail ERsnail (Homo sapiens)Mammalian Expression, RetroviralThe epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008 May 16. 133(4):704-15. pWZL-Blast SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 Add to Cart
18799pWZL Blast Twist ERtwist (Mus musculus)Mammalian Expression, RetroviralThe epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008 May 16. 133(4):704-15. pWZL-Blast Twist1 M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt Add to Cart
18800pWZL Blast DN E-cadherinDom neg E-cadherin (Mus musculus)Mammalian Expression, RetroviralLoss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008 May 15. 68(10):3645-54. pWZL-Blast Cdh1 AA960649, ARC-1, E-cad, Ecad, L-CAM, UVO, Um Add to Cart
18801pLKO.1 puro shRNA E-cadherinE-cadherin shRNA (Homo sapiens)Mammalian Expression, Lentiviral, RNAiLoss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008 May 15. 68(10):3645-54. pLKO.1 puro CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO Add to Cart
18802pLKO.1 hygro shRNA E-cadherinE-cadherin shRNA (Homo sapiens)Mammalian Expression, Lentiviral, RNAiLoss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008 May 15. 68(10):3645-54. pLKO.1 hygro CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO Add to Cart
18803pLKO.1 puro shRNA beta-cateninb-catenin shRNA (Homo sapiens)Mammalian Expression, Lentiviral, RNAiLoss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008 May 15. 68(10):3645-54. 3rd gen lentiviral vector for knocking down beta-catenin gene expression pLKO.1 puro CTNNB1 CTNNB, MRD19, armadillo Add to Cart
18804pWZL Blast mouse E-cadherinE-cadherin (Mus musculus)Mammalian Expression, RetroviralLoss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008 May 15. 68(10):3645-54. pWZL-Blast Cdh1 AA960649, ARC-1, E-cad, Ecad, L-CAM, UVO, Um Add to Cart
19116pMIR-D10 mutUTRHOXD10 mut 3' UTR (Homo sapiens)Mammalian ExpressionTumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature. 2007 Oct 11. 449(7163):682-8. pMIR-report HOXD10 HOX4, HOX4D, HOX4E, Hox-4.4 Add to Cart
19117pMIR-D10 UTRHOXD10 3' UTR (Homo sapiens)Mammalian ExpressionTumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature. 2007 Oct 11. 449(7163):682-8. pMIR-report HOXD10 HOX4, HOX4D, HOX4E, Hox-4.4 Add to Cart
19118pMIR-10bmicroRNA 10b (Homo sapiens)Mammalian ExpressionTumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature. 2007 Oct 11. 449(7163):682-8. pMIR-report MIR10B MIRN10B, hsa-mir-10b, miRNA10B, mir-10b Add to Cart
19119shp53 pLKO.1 purosmall hairpin RNA against tumor protein p53 (Homo sapiens)Mammalian Expression, Lentiviral, RNAiGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. 3rd gen lentiviral vector for knocking down p53 gene expression pLKO.1 puro TP53 BCC7, LFS1, P53, TRP53 Add to Cart
19120shp63alpha pLKO.1 purosmall hairpin RNA against tumor protein p63 (Homo sapiens)Mammalian Expression, Lentiviral, RNAiGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. pLKO.1 puro TP63 AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L Add to Cart
19122CD44P pGL3CD44 promoter (Homo sapiens)Non viral cloning vectorGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. pGL3-Basic CD44 CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 Add to Cart
19123shCD44-2 pRRLsmall hairpin RNA against CD44 (Homo sapiens)Mammalian Expression, LentiviralGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. pRRL-U6-siluc-cppt-hPGKGFPSIN CD44 CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 Add to Cart
19125shLuc pRRLcontrol shRNAMammalian Expression, LentiviralGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. pRRL-U6-siluc-cppt-hPGKGFPSIN Add to Cart
19126CD44S pWZL-BlastCD44 standard (Homo sapiens)Mammalian Expression, RetroviralGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. pWZL Blast CD44 CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 Add to Cart
19127CD44S pBabe-puroCD44 standard (Homo sapiens)Mammalian Expression, RetroviralGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11. 134(1):62-73. pBABE-puro CD44 CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 Add to Cart
21295pBabe puro MTH1MTH1 (Homo sapiens)Mammalian Expression, RetroviralContinuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pBABE-puro NUDT1 MTH1 Add to Cart
21296pBabe hygro MTH1MTH1 (Homo sapiens)Mammalian Expression, RetroviralContinuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pBABE-hygro NUDT1 MTH1 Add to Cart
21297pLKO.1 shMTH1-1shMTH1-1 (Homo sapiens)Mammalian Expression, Lentiviral, RNAiContinuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pLKO.1 puro NUDT1 MTH1 Add to Cart
21298pLKO.1 shMTH1-2shMTH1-2 (Homo sapiens)Mammalian Expression, Lentiviral, RNAiContinuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pLKO.1 puro NUDT1 MTH1 Add to Cart
22693pISI-mmP16 3' UTRmmP16 3'UTRMammalian ExpressionA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
22694pBABE-puro-mIR-31 spongemiR-31 (Homo sapiens)Mammalian Expression, RetroviralA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. Stable suppression of miR-31 function pBABE-puro MIR31 MIRN31, hsa-mir-31, miR-31 Add to Cart
22744pBp-Control Sponge (CXCR4 sponge)CXCR4 control spongeMammalian Expression, RetroviralA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pBABE-puro Add to Cart
23347pBabe puro SnailSnail (Homo sapiens)Mammalian Expression, RetroviralMesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci U S A. 2007 Jun 12. 104(24):10069-74. pBabe puro SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 Add to Cart
24150pLKO.1 hygroMammalian Expression, Lentiviral, RNAi empty vector (unpublished) 3rd gen lentiviral backbone for cloning and expression of new shRNA sequences. Uses hygromycin for selection. pLKO.1 - TRC cloning vector (no stuffer) Add to Cart
25021pIS1-miR-31 sitesynthetic miR-31 siteMammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
25023pIS1-mutant Fzd3 3'UTRmutant Fzd3 3'UTRMammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
25024pIS1-wt Fzd3 3'UTRwt Fzd3 3'UTRMammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
25025CMV-miR-31 spongeCMV-miR-31 spongeMammalian ExpressionA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pcDNA5-CMV-d2eGFP Add to Cart
25026pIS1-miR-126 sitesynthetic miR-126 siteMammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
25027pIS1-miR-206 sitesynthetic miR-206 siteMammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
25028pIS1-miR-335 sitesynthetic miR-335 siteMammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 Add to Cart
25036MDH1-PGK-GFP-miR9mir-9-3 (Homo sapiens)Mammalian Expression, Retroviral, RNAimiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010 Mar . 12(3):247-56. MDH1-PGK-GFP 2.0 MIR9-3 MIRN9-3, miRNA9-3, hsa-mir-9-3 Add to Cart
25037pMIR-9miR-9 binding site (Homo sapiens)Mammalian Expression, LuciferasemiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010 Mar . 12(3):247-56. pMIR-report Add to Cart
25038pMIR-CDH1 wtUTRCDH1 3'UTR (Homo sapiens)Mammalian Expression, LuciferasemiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010 Mar . 12(3):247-56. pMIR-report CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO Add to Cart
25039pMIR-CDH1 mutUTRCDH1 mutant 3'UTR (Homo sapiens)Mammalian Expression, LuciferasemiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010 Mar . 12(3):247-56. pMIR-report CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO Add to Cart
25040pBabe-puro-miR-9 spongemiR-9 spongeMammalian Expression, RetroviralmiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010 Mar . 12(3):247-56. pBabe-puro Add to Cart
25043pBabe-puro-miR-10b spongemiR-10b spongeMammalian Expression, RetroviralTherapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol. 2010 Apr . 28(4):341-7. pBabe-puro Add to Cart
26085pSVE Grb2 myc 49LGrb2 P49L (Homo sapiens)Mammalian ExpressionAssociation of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 1993 May 6. 363(6424):45-51. pSVE GRB2 ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 Add to Cart
26087pSVE Grb2 myc 49L/203RGrb2 49L/203R (Homo sapiens)Mammalian ExpressionAssociation of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 1993 May 6. 363(6424):45-51. pSVE GRB2 ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 Add to Cart
26088pBabe-puro-mIR-31miR-31 (Homo sapiens)Mammalian Expression, RetroviralA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pBABE-puro MIR31 MIRN31, hsa-mir-31, miR-31 Add to Cart
26089pIS1-wt RhoA 3'UTRwt RhoA 3'UTR (Homo sapiens)Mammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 RHOA ARH12, ARHA, RHO12, RHOH12 Add to Cart
26090pIS1-mutant RhoA 3'UTRmutant RhoA 3'UTR (Homo sapiens)Mammalian Expression, LuciferaseA pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009 Jun 12. 137(6):1032-46. pIS1 RHOA ARH12, ARHA, RHO12, RHOH12 Add to Cart
36976pTK-SnailSnail (Mus musculus)LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pTK380 (tetracycline inducible) Snai1 Sna, Sna1, Snail, Snail1 Add to Cart
36977pTK-TwistTwistLentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pTK380 (tetracycline inducible) Twist1 M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt Add to Cart
36978FUW-Sox10Sox10 (Homo sapiens)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. FUW-LPT2 (tetracycline-inducible) SOX10 DOM, PCWH, WS2E, WS4, WS4C Add to Cart
36979pWPXL-Sox9Sox9 (Mus musculus)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pWPXL Sox9 2010306G03Rik, AV220920, mKIAA4243 Add to Cart
36980pWPXL-c-Mycc-Myc (Mus musculus)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pWPXL Myc AU016757, Myc2, Niard, Nird, bHLHe39 Add to Cart
36981pWPXL-Klf4Klf4 (Mus musculus)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pWPXL Klf4 EZF, Gklf, Zie Add to Cart
36983pWPXL-Hes1Hes1 (Mus musculus)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pWPXL Hes1 Hry, bHLHb39 Add to Cart
36984pWPXL-Sox4Sox4 (Homo sapiens)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pWPXL SOX4 EVI16 Add to Cart
36985pLV-beta-catenin deltaN90beta-catenin deltaN90 (Homo sapiens)Mammalian Expression, LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLV-IRES-neo CTNNB1 CTNNB, MRD19, armadillo Add to Cart
36986pTK-Slugslug (Mus musculus)LentiviralSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pTK380 (tetracycline inducible) Snai2 Slug, Slugh, Snail2 Add to Cart
37007pLKO.1-sh-mSox10-2sh-mSox10-2 (Mus musculus)Mammalian Expression, Lentiviral, RNAiSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Sox10 Dom, Sox21, gt Add to Cart
37013pLV-neo-CD2-FAKCD2-FAK (Homo sapiens)Mammalian Expression, LentiviralIntegrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5. pLV-IRES-neo CD2 LFA-2, SRBC, T11 PTK2 FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK Add to Cart
37015pLKO-puro-sh-mFAK Csh-mFAK C (Mus musculus)Mammalian Expression, Lentiviral, RNAiIntegrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5. pLKO.1 puro (Addgene plasmid 8453) Ptk2 FAK, FRNK, Fadk, mKIAA4203, p125FAK Add to Cart
37018pLKO-puro-sh-mFAK Bsh-mFAK B (Mus musculus)Mammalian Expression, Lentiviral, RNAiIntegrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5. pLKO.1 puro (Addgene plasmid 8453) Ptk2 FAK, FRNK, Fadk, mKIAA4203, p125FAK Add to Cart
40644pLKO.1-sh-hSOX9-1sh-hSOX9-1 (Homo sapiens)Mammalian Expression, Lentiviral, RNAiSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Add to Cart
40645pLKO.1-sh-mSOX9-2sh-mSOX9-2 (Mus musculus)Mammalian Expression, Lentiviral, RNAiSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Add to Cart
40646pLKO.1-sh-mSOX9-5sh-mSOX9-5 (Mus musculus)Mammalian Expression, Lentiviral, RNAiSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Add to Cart
40647pLKO.1-sh-mSlug-3sh-mSlug-3 (Mus musculus)Mammalian Expression, Lentiviral, RNAiSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Add to Cart
40648pLKO.1-sh-mSlug-4sh-mSlug-4 (Mus musculus)Mammalian Expression, Lentiviral, RNAiSlug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Add to Cart