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Carl Novina Lab Plasmids


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Title Authors Publication
Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Horman SR, Janas MM, Litterst C, Wang B, MacRae IJ, Sever MJ, Morrissey DV, Graves P, Luo B, Umesalma S, Qi HH, Miraglia LJ, Novina CD, Orth AP Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18.
Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S, Chen PH, Li S, Fletcher AL, Yokoyama S, Scott KL, Garraway LA, Song JS, Granter SR, Turley SJ, Fisher DE, Novina CD Mol Cell. 2010 Dec 10. 40(5):841-9.
Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Wang B, Li S, Qi HH, Chowdhury D, Shi Y, Novina CD Nat Struct Mol Biol. 2009 Dec . 16(12):1259-66.
Recapitulation of short RNA-directed translational gene silencing in vitro. Wang B, Love TM, Call ME, Doench JG, Novina CD Mol Cell. 2006 May 19. 22(4):553-60.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
12563 PCD FL0X Mammalian Expression, Luciferase ; Reporter for translation repression Recapitulation of short RNA-directed translational gene silencing in vitro. Mol Cell. 2006 May 19. 22(4):553-60. pcDNA3.1 Add to Cart
12564 PCD FL2X Two CXCR4 imperfect binding sites (Homo sapiens) Mammalian Expression, Luciferase ; Reporter for translation repression Recapitulation of short RNA-directed translational gene silencing in vitro. Mol Cell. 2006 May 19. 22(4):553-60. pcDNA3.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
12565 PCD FL4X Four CXCR4 imperfect binding sites (Homo sapiens) Mammalian Expression, Luciferase ; Reporter for translation repression Recapitulation of short RNA-directed translational gene silencing in vitro. Mol Cell. 2006 May 19. 22(4):553-60. pcDNA3.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
12566 PCD FL6X Four CXCR4 imperfect binding sites (Homo sapiens) Mammalian Expression, Luciferase ; Reporter for translation repression Recapitulation of short RNA-directed translational gene silencing in vitro. Mol Cell. 2006 May 19. 22(4):553-60. pcDNA3.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
12567 PCD FL1P One perfect CXCR4 binding site (Homo sapiens) Mammalian Expression, Luciferase ; Reporter for translation repression Recapitulation of short RNA-directed translational gene silencing in vitro. Mol Cell. 2006 May 19. 22(4):553-60. pcDNA3.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
24316 pGEX-GST-AGO1 human AGO1 (Homo sapiens) Bacterial Expression Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol. 2009 Dec . 16(12):1259-66. pGEX-4T1 AGO1 EIF2C, EIF2C1, GERP95, Q99 Add to Cart
24317 pGEX-GST-AGO2 human AGO2 (Homo sapiens) Bacterial Expression Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol. 2009 Dec . 16(12):1259-66. pGEX-4T-1 AGO2 EIF2C2, Q10 Add to Cart
24318 pGEX-GST-AGO3 AGO3 (Homo sapiens) Bacterial Expression Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol. 2009 Dec . 16(12):1259-66. pGEX-4T-1 AGO3 RP4-789D17.2, EIF2C3 Add to Cart
24319 pGEX-GST-AGO4 AGO4 (Homo sapiens) Bacterial Expression Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol. 2009 Dec . 16(12):1259-66. pGEX-4T-1 AGO4 EIF2C4 Add to Cart
29780 PLKO-mcherry-luc-puro-shSCR shSCR Mammalian Expression, Lentiviral, RNAi Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell. 2010 Dec 10. 40(5):841-9. PLKO (modified) Add to Cart
29782 PLKO-mcherry-luc-puro-TRPM1 cDNA TRPM1 (Homo sapiens) Mammalian Expression, Lentiviral Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell. 2010 Dec 10. 40(5):841-9. PLKO (modified) TRPM1 CSNB1C, LTRPC1, MLSN1 Add to Cart
29783 PLKO-mcherry-luc-puro-Renilla cDNA Renilla Mammalian Expression, Lentiviral Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell. 2010 Dec 10. 40(5):841-9. PLKO modified Add to Cart
29784 PLKO-mcherry-luc-puro-miR-211 miR-211 Mammalian Expression, Lentiviral, RNAi Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell. 2010 Dec 10. 40(5):841-9. PLKO (modified) Add to Cart
59904 pDEST26 Ago2 Argonaute 2 (Homo sapiens) Mammalian Expression Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18. Expresses 6xHis-Ago2 (N-termi tag) in mammalian cells pDEST 26 AGO2 EIF2C2, Q10 Add to Cart
59905 pDEST26 Ago2 S387A Argonaute 2 (Homo sapiens) Mammalian Expression Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18. Expresses 6xHis-Ago2 (N-termi tag) S387A mutant in mammalian cells pDEST 26 AGO2 EIF2C2, Q10 Add to Cart
59906 pDEST26 Ago2 S387E Argonaute 2 (Homo sapiens) Mammalian Expression Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18. Expresses 6xHis-Ago2 (N-termi tag) S387E mutant in mammalian cells pDEST 26 AGO2 EIF2C2, Q10 Add to Cart
59907 pDEST26 Ago2 4A Argonaute 2 (Homo sapiens) Mammalian Expression Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18. Expresses 6xHis-Ago2 (N-termi tag) mutated four serines to alanines in mammalian cells pDEST 26 AGO2 EIF2C2, Q10 Add to Cart
60651 pDEST26 Ago2 5A Argonaute 2 (Homo sapiens) Mammalian Expression Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18. Expresses 6xHis-Ago2 (N-termi tag) mutated five serines to alanines in mammalian cells pDEST 26 AGO2 EIF2C2, Q10 Add to Cart
60654 pHAGE GFP-Ago2 S387A Argonaute 2 (Homo sapiens) Lentiviral Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18. GFP-Ago2 S387A mutant lentiviral vector pHAGE AGO2 EIF2C2, Q10 Add to Cart