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David Sabatini Lab Plasmids


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Title Authors Publication
Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, Wood KC Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877.
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM Cell. 2014 Aug 28;158(5):1094-109. doi: 10.1016/j.cell.2014.07.032.
Genetic screens in human cells using the CRISPR-Cas9 system. Wang T, Wei JJ, Sabatini DM, Lander ES Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12.
mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Kang SA, Pacold ME, Cervantes CL, Lim D, Lou HJ, Ottina K, Gray NS, Turk BE, Yaffe MB, Sabatini DM Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566.
A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044.
Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Bar-Peled L, Schweitzer LD, Zoncu R, Sabatini DM Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032.
A unifying model for mTORC1-mediated regulation of mRNA translation. Thoreen CC, Chantranupong L, Keys HR, Wang T, Gray NS, Sabatini DM Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083.
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H-ATPase. Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, Sabatini DM Science. 2011 Nov 4;334(6056):678-83.
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM Cell. 2011 Aug 5;146(3):408-20.
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM Science. 2011 Jun 10;332(6035):1317-22.
Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo. Sheen JH, Zoncu R, Kim D, Sabatini DM Cancer Cell. 2011 May 17. 19(5):613-28.
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM Cell. 2010 Apr 16. 141(2):290-303.
DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM Cell. 2009 May 13. ():.
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. Thoreen CC, Kang SA, Chang JW, Liu Q, Zhang J, Gao Y, Reichling LJ, Sim T, Sabatini DM, Gray NS J Biol Chem. 2009 Mar 20. 284(12):8023-32.
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501.
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM Mol Cell. 2007 Mar 23. 25(6):903-15.
mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Frias MA, Thoreen CC, Jaffe JD, Schroder W, Sculley T, Carr SA, Sabatini DM Curr Biol. 2006 Aug 15. ():.
Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. Ali SM, Sabatini DM J Biol Chem 2005 Apr 4;.
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Sarbassov DD, Guertin DA, Ali SM, Sabatini DM Science 2005 Feb 18;307(5712):1098-101.
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM Curr Biol 2004 Jul 27;14(14):1296-302.
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM Mol Cell 2003 Apr;11(4):895-904.
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM Cell 2002 Jul 26;110(2):163-75.
pLJM1-Flag (unpublished)
Unpublished plasmid (unpublished)
myc mTOR kinase dead (unpublished)
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
1853 Rictor_1 shRNA Rictor (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. pLKO.1 RICTOR AVO3, PIA, hAVO3 Add to Cart
1854 Rictor_2 shRNA Rictor (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. pLKO.1 RICTOR AVO3, PIA, hAVO3 Add to Cart
1855 mTOR_1 shRNA mTOR (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. pLKO.1 MTOR FRAP, FRAP1, FRAP2, RAFT1, RAPT1 Add to Cart
1856 mTOR_2 shRNA mTOR (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. pLKO.1 MTOR FRAP, FRAP1, FRAP2, RAFT1, RAPT1 Add to Cart
1857 Raptor_1 shRNA Raptor (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. pLKO.1 RPTOR KOG1, Mip1 Add to Cart
1858 Raptor_2 shRNA Raptor (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. pLKO.1 RPTOR KOG1, Mip1 Add to Cart
1859 myc-Raptor Raptor (Homo sapiens) Mammalian Expression Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004 Jul 27;14(14):1296-302. pRK-5 RPTOR KOG1, Mip1 Add to Cart
1860 myc-Rictor Rictor (Homo sapiens) Mammalian Expression Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004 Jul 27;14(14):1296-302. pRK-5 RICTOR AVO3, PIA, hAVO3 Add to Cart
1861 myc-mTOR mTOR (Rattus norvegicus) Mammalian Expression Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004 Jul 27;14(14):1296-302. pRK5 Mtor Frap1, RAFT1 Add to Cart
1864 scramble shRNA scramble Mammalian Expression, Lentiviral, RNAi Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005 Feb 18;307(5712):1098-101. 3rd gen lentiviral negative control vector containing scrambled shRNA pLKO.1 Add to Cart
1865 HA-GbL GbL (Homo sapiens) Mammalian Expression Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004 Jul 27;14(14):1296-302. pRK-5 MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
8463 delta NT delta CT p70S6K1 MSCV puro delta NT delta CT p70 S6K1 (Rattus norvegicus) Mammalian Expression, Retroviral Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005 Apr 4;. mscv puro Rps6kb1 Add to Cart
8464 F5A deltaCT S6K1 MSCV puro f5a delta ctp70 S6K1 (Rattus norvegicus) Mammalian Expression, Retroviral Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005 Apr 4;. mscv puro Rps6kb1 Add to Cart
8465 deltaCT S6K1 MSCV puro delta ct p70 S6K1 (Rattus norvegicus) Mammalian Expression, Retroviral Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005 Apr 4;. mscv puro Rps6kb1 Add to Cart
8466 HA GST p85 S6K1 pRK5 p85 s6k1 (Rattus norvegicus) Mammalian Expression Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005 Apr 4;. prk5 Rps6kb1 Add to Cart
8467 HA GST F5A deltaCT S6K1 pRK5 f5a delta CT p85 s6k1 (Rattus norvegicus) Mammalian Expression Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005 Apr 4;. prk5 Rps6kb1 Add to Cart
8468 HA GST deltaCT S6K1 pRK5 delta CT p85 s6k1 (Rattus norvegicus) Mammalian Expression Structure of S6K1 determines if raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005 Apr 4;. prk5 Rps6kb1 Add to Cart
8470 HA Raptor mutant 1 Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
8471 HA Raptor mutant 2 Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
8473 HA Raptor mutant 3 Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
8474 HA Raptor mutant 4 Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
8475 HA Raptor mutant 7 Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
8476 HA Raptor mutant 9 Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
8477 myc GbetaL mutant 1 GbetaL (Homo sapiens) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. prk5 MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
8478 myc GbetaL mutant 2 GbetaL (Homo sapiens) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. prk5 MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
8479 myc GbetaL mutant 5 GbetaL (Homo sapiens) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. prk5 MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
8480 myc GbetaL mutant 6 GbetaL (Homo sapiens) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. prk5 MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
8481 myc GbetaL mutant 7 GbetaL (Homo sapiens) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. prk5 MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
8482 myc mTOR kinase dead mTOR (Rattus norvegicus) Mammalian Expression myc mTOR kinase dead (unpublished) prk5 Mtor Frap1, RAFT1 Add to Cart
8513 HA Raptor Raptor (Homo sapiens) Mammalian Expression mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002 Jul 26;110(2):163-75. prk5 RPTOR KOG1, Mip1 Add to Cart
11367 myc-Rictor corrected Rictor (Homo sapiens) Mammalian Expression Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004 Jul 27;14(14):1296-302. Mammalian expression of myc tagged human RICTOR pRK-5 RICTOR AVO3, PIA, hAVO3 Add to Cart
12570 pMSCV-TAP Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV-TAP Add to Cart
12575 pMSCV-TAP mLST8 (aka: GbL) mLST8 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV-TAP MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
12576 pMSCV mSin1.1 myc mSin1.1 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
12577 pMSCV mSin1.2 myc mSin1.2 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
12578 pMSCV mSin1.4 myc mSin1.4 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
12579 pMSCV mSin1.5 myc mSin1.5 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
12580 pMSCV mLST8 myc (aka: GbL-myc) mLST8 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MLST8 GBL, GbetaL, LST8, POP3, WAT1 Add to Cart
12581 pMSCV tubulin myc tubulin (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV TUBG1 CDCBM4, GCP-1, TUBG, TUBGCP1 Add to Cart
12582 pMSCV mSin1.1 HA mSin1.1 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
12583 pMSCV mSin1.2 HA mSin1.2 (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
12587 pMSCV-TAP Raptor Raptor (Homo sapiens) Mammalian Expression, Retroviral mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pMSCV RPTOR KOG1, Mip1 Add to Cart
13483 mSin1 shRNA #1 mSin1 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pLKO.1 MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
13484 mSin1 shRNA #2 mSin1 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s. Curr Biol. 2006 Aug 15. ():. pLKO.1 MAPKAP1 RP11-269P11.1, JC310, MIP1, SIN1, SIN1b, SIN1g Add to Cart
14950 pRK5 Flag PRAS40 PRAS40 (Homo sapiens) Mammalian Expression PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell. 2007 Mar 23. 25(6):903-15. Flag-pRK5 AKT1S1 Lobe, PRAS40 Add to Cart
14951 pRK5 HA GST Rheb1 Rheb1 (Homo sapiens) Mammalian Expression PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell. 2007 Mar 23. 25(6):903-15. HA-GST-pRK5 RHEBP1 RHEB, RHEB1 Add to Cart
14952 pRK5 HA GST rap2a rap2a (Homo sapiens) Mammalian Expression PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell. 2007 Mar 23. 25(6):903-15. HA-GST-pRK5 RAP2A K-REV, KREV, RAP2, RbBP-30 Add to Cart
15511 HA GST PreScission p70 S6K1 p70 S6K1 (Rattus norvegicus) Mammalian Expression PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell. 2007 Mar 23. 25(6):903-15. HA-GST-pRK5 Rps6kb1 Add to Cart
17923 pMT-puro Insect Expression ; Drosophila metallothionein gene promoter drives expression Unpublished plasmid (unpublished) Insect expression vector pMT-puro Add to Cart
19298 pRK5-HA GST RagA wt Ras-related GTP binding A (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGA FIP-1, FIP1, RAGA Add to Cart
19299 pRK5-HA GST RagA 21L Ras-related GTP binding A (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGA FIP-1, FIP1, RAGA Add to Cart
19300 pRK5-HA GST RagA 66L Ras-related GTP binding A (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGA FIP-1, FIP1, RAGA Add to Cart
19301 pRK5-HA GST RagB wt Ras-related GTP binding B (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
19302 pRK5-HA GST RagB 54L Ras-related GTP binding B (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
19303 pRK5-HA GST RagB 99L Ras-related GTP binding B (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
19304 pRK5-HA GST RagC wt Ras-related GTP binding C (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGC GTR2, RAGC, TIB929 Add to Cart
19305 pRK5-HA GST RagC 75L Ras-related GTP binding C (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGC GTR2, RAGC, TIB929 Add to Cart
19306 pRK5-HA GST RagC 120L Ras-related GTP binding C (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGC GTR2, RAGC, TIB929 Add to Cart
19307 pRK5-HA GST RagD wt Ras-related GTP binding D (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGD RAGD, bA11D8.2.1 Add to Cart
19308 pRK5-HA GST RagD 77L Ras-related GTP binding D (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGD RAGD, bA11D8.2.1 Add to Cart
19309 pRK5-HA GST RagD 121L Ras-related GTP binding D (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RRAGD RAGD, bA11D8.2.1 Add to Cart
19310 pRK5-HA GST Rheb1 RHEB Ras homolog enriched in brain (Homo sapiens) Mammalian Expression The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pRK5 RHEB RHEB2 Add to Cart
19311 Flag pLJM1 Rap2A RAP2A, member of RAS oncogene family (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RAP2A K-REV, KREV, RAP2, RbBP-30 Add to Cart
19312 Flag pLJM1 Rheb1 RHEB Ras homolog enriched in brain (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RHEB RHEB2 Add to Cart
19313 Flag pLJM1 RagB wt Ras-related GTP binding B (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
19314 Flag pLJM1 RagB 54L Ras-related GTP binding B (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
19315 Flag pLJM1 RagB 99L Ras-related GTP binding B (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
19316 Flag pLJM1 RagD wt Ras-related GTP binding D (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RRAGD RAGD, bA11D8.2.1 Add to Cart
19317 Flag pLJM1 RagD 77L Ras-related GTP binding D (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RRAGD RAGD, bA11D8.2.1 Add to Cart
19318 Flag pLJM1 RagD 121L Ras-related GTP binding D (Homo sapiens) Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLJM1 RRAGD RAGD, bA11D8.2.1 Add to Cart
19319 pLJM1-EGFP none Mammalian Expression, Lentiviral The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. 3rd gen lentiviral vector for EGFP fusion; PGK driven puromycin pLJM1
  • Tag / Fusion Protein
    • EGFP
  • Add to Cart
    21334 pRK5 FLAG human DEPTOR DEPTOR (Homo sapiens) Mammalian Expression DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pRK5-FLAG DEPTOR DEP.6, DEPDC6 Add to Cart
    21335 pLKO human shRNA 1 DEPTOR DEPTOR shRNA 1 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 DEPTOR DEP.6, DEPDC6 Add to Cart
    21336 pLKO human shRNA 2 DEPTOR DEPTOR shRNA 2 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 DEPTOR DEP.6, DEPDC6 Add to Cart
    21337 pLKO mouse shRNA 1 DEPTOR DEPTOR shRNA 1 (Mus musculus) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 Deptor 4731402B04Rik, 9130412E02Rik, D15Ertd336e, D15Ertd597e, Depdc6, Depdc6-001, Depdc6-002, R75183, mKIAA4200 Add to Cart
    21338 pLKO mouse shRNA 2 DEPTOR DEPTOR shRNA 2 (Mus musculus) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 Deptor 4731402B04Rik, 9130412E02Rik, D15Ertd336e, D15Ertd597e, Depdc6, Depdc6-001, Depdc6-002, R75183, mKIAA4200 Add to Cart
    21339 pLKO mouse shRNA 1 raptor raptor shRNA 1 (Mus musculus) Mammalian Expression, Lentiviral, RNAi An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J Biol Chem. 2009 Mar 20. 284(12):8023-32. pLKO.1 Rptor RP24-225K18.1, 4932417H02Rik, Rap, Raptor, mKIAA1303 Add to Cart
    21340 pLKO mouse shRNA 2 raptor raptor shRNA 2 (Mus musculus) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 Add to Cart
    21341 pLKO mouse shRNA 1 rictor rictor shRNA 1 (Mus musculus) Mammalian Expression, Lentiviral, RNAi An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J Biol Chem. 2009 Mar 20. 284(12):8023-32. pLKO.1 Rictor 4921505C17Rik, 6030405M08Rik, AVO3, AW492497, D530039E11Rik Add to Cart
    21700 pRK5 FLAG DEPTOR (DEP domains) DEPTOR DEP domains (Homo sapiens) Mammalian Expression DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pRK5-FLAG DEPTOR DEP.6, DEPDC6 Add to Cart
    21701 pRK5 FLAG DEPTOR (PDZ domain) DEPTOR PDZ domain (Homo sapiens) Mammalian Expression DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pRK5-FLAG DEPTOR DEP.6, DEPDC6 Add to Cart
    21702 pRK5 FLAG DEPTOR (13×S/T->A) DEPTOR 13xA (Homo sapiens) Mammalian Expression DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pRK5-FLAG DEPTOR DEP.6, DEPDC6 Add to Cart
    21745 myc-mTOR (1-1482 aa) mTOR (1-1482) (Rattus norvegicus) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. pRK5 Mtor Frap1, RAFT1 Add to Cart
    21746 myc-mTOR (1271-2008 aa) mTOR (1271-2008) (Rattus norvegicus) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. pRK5 Mtor Frap1, RAFT1 Add to Cart
    21747 myc-mTOR (1750-2549 aa) mTOR (1750-2549) (Rattus norvegicus) Mammalian Expression GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904. pRK5 Mtor Frap1, RAFT1 Add to Cart
    26625 pLKO.1 Rheb1 shRNA #1 Rheb1 shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RHEBP1 RHEB, RHEB1 Add to Cart
    26626 pLKO.1 Rheb1 shRNA #2 Rheb1 shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RHEBP1 RHEB, RHEB1 Add to Cart
    26627 pLKO.1 RagB shRNA #1 RagB shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
    26628 pLKO.1 RagB shRNA #2 RagB shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
    26629 pLKO.1 RagC shRNA #1 RagC shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGC GTR2, RAGC, TIB929 Add to Cart
    26630 pLKO.1 RagC shRNA #2 RagC shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGC GTR2, RAGC, TIB929 Add to Cart
    26631 pLKO.1 p18 shRNA p18 shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16. 141(2):290-303. pLKO.1 puro LAMTOR1 PP7157, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho Add to Cart
    26632 pLKO.1 MP1 shRNA MP1 shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16. 141(2):290-303. pLKO.1 puro LAMTOR3 MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3 Add to Cart
    26633 pLJM1 Flag Raptor raptor (Homo sapiens) Mammalian Expression, Lentiviral Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16. 141(2):290-303. pLJM1 RPTOR KOG1, Mip1 Add to Cart
    26634 pLJM1 Flag Raptor Rheb15 raptor-Rheb15 (Homo sapiens) Mammalian Expression, Lentiviral Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16. 141(2):290-303. pLJM1 RPTOR KOG1, Mip1 Add to Cart
    26637 pLJM1 Flag Raptor HRas25 raptor-HRas25 (Homo sapiens) Mammalian Expression, Lentiviral Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16. 141(2):290-303. pLJM1 RPTOR KOG1, Mip1 Add to Cart
    26638 pLJM1 p18 mito p18 mito (Homo sapiens) Mammalian Expression, Lentiviral Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16. 141(2):290-303. pLJM1 LAMTOR1 PP7157, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho Add to Cart
    29432 pLKO human shRNA 1 c-MAF c-MAF shRNA 1 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 MAF CCA4, c-MAF Add to Cart
    29433 pLKO human shRNA 2 c-MAF c-MAF shRNA 2 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival. Cell. 2009 May 13. ():. pLKO.1 MAF CCA4, c-MAF Add to Cart
    30319 pLKO.1 RagA shRNA #1 RagA shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGA FIP-1, FIP1, RAGA Add to Cart
    30320 pLKO.1 RagA shRNA #2 RagA shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGA FIP-1, FIP1, RAGA Add to Cart
    30321 pLKO.1 RagD shRNA #1 RagD shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGD RAGD, bA11D8.2.1 Add to Cart
    30322 pLKO.1 RagD shRNA #2 RagD shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro RRAGD RAGD, bA11D8.2.1 Add to Cart
    30323 pLKO.1 GFP shRNA GFP shRNA Mammalian Expression, Lentiviral, RNAi The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13. 320(5882):1496-501. pLKO.1 puro Add to Cart
    31182 pQCXI Puro DsRed-LC3-GFP DsRed-LC3-GFP Mammalian Expression, Retroviral Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo. Cancer Cell. 2011 May 17. 19(5):613-28. pQCXIP Add to Cart
    31183 pQCXI Neo DsRed-LC3-GFP DsRed-LC3-GFP Mammalian Expression, Retroviral Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo. Cancer Cell. 2011 May 17. 19(5):613-28. pQCXIN Add to Cart
    32004 pRK5 FLAG metap2 metap2 Mammalian Expression mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pRK5 Metap2 4930584B20Rik, A930035J23Rik, AI047573, AL024412, AU014659, Amp2, MGC102452, Mnpep, p67, p67eIF2 Add to Cart
    32005 pRK5 FLAG wildtype, catalytic active lipin 1 lipin1 (Mus musculus) Mammalian Expression mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pRK5
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Lpin1 4631420P06, Kiaa0188, Lipin1, fld, mKIAA0188
    Add to Cart
    32006 pRK5 FLAG wildtype, catalytic dead lipin 1 Lipin1 (Mus musculus) Mammalian Expression mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pRK5 Lpin1 4631420P06, Kiaa0188, Lipin1, fld, mKIAA0188 Add to Cart
    32007 pRK5 FLAG 17xS/T->A, catalytic active lipin 1 lipin1 (Mus musculus) Mammalian Expression mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pRK5
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Lpin1 4631420P06, Kiaa0188, Lipin1, fld, mKIAA0188
    Add to Cart
    32008 pRK5 FLAG 17xS/T->A, catalytic dead lipin 1 Lipin1 (Mus musculus) Mammalian Expression mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pRK5
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Lpin1 4631420P06, Kiaa0188, Lipin1, fld, mKIAA0188
    Add to Cart
    32010 pLKO-puro FLAG wildtype, catalytic active lipin 1 lipin1 (Mus musculus) Mammalian Expression, Lentiviral mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pLKO.1-puro
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Lpin1 4631420P06, Kiaa0188, Lipin1, fld, mKIAA0188
    Add to Cart
    32017 pLKO-puro FLAG SREBP1 SREBP1 (Mus musculus) Mammalian Expression, Lentiviral mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pLKO.1-puro Srebf1 ADD-1, ADD1, D630008H06, SREBP-1, SREBP-1a, SREBP-1c, SREBP1, SREBP1c, bHLHd1 Add to Cart
    32018 pLKO-puro FLAG SREBP2 SREBP2 (Mus musculus) Mammalian Expression, Lentiviral mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pLKO.1-puro
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Srebf2 AI608257, SREBP-2, SREBP2, SREBP2gc, bHLHd2, lop13, nuc
    Add to Cart
    32019 pLKO-puro human lipin 1-1 shRNA lipin1 shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway. Cell. 2011 Aug 5;146(3):408-20. pLKO.1-TRC Add to Cart
    34610 pLJM60 deptor (Homo sapiens) Mammalian Expression, Lentiviral pLJM1-Flag (unpublished) pLJM1-Flag DEPTOR DEP.6, DEPDC6 Add to Cart
    34611 LAMP1-mRFP-FLAG LAMP1 (Rattus norvegicus) Mammalian Expression, Lentiviral mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H-ATPase. Science. 2011 Nov 4;334(6056):678-83. 3rd gen lentiviral vector expressing a fusion protein of Lamp1, mRFP, and a FLAG tag pLJM1 Add to Cart
    37481 pRK5 Flag Grb10 wt long Grb10 (Homo sapiens) Mammalian Expression The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science. 2011 Jun 10;332(6035):1317-22. pRK5-FLAG GRB10 GRB-IR, Grb-10, IRBP, MEG1, RSS Add to Cart
    37484 pRK5 Flag Grb10 5A short Grb10 5A (Homo sapiens) Mammalian Expression The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science. 2011 Jun 10;332(6035):1317-22. pRK5-FLAG
  • Tag / Fusion Protein
    • Flag (N terminal on backbone)
  • GRB10 GRB-IR, Grb-10, IRBP, MEG1, RSS
    Add to Cart
    37485 pRK5 Flag Grb10 9A long Grb10 9A (Homo sapiens) Mammalian Expression The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science. 2011 Jun 10;332(6035):1317-22. pRK5-FLAG
  • Tag / Fusion Protein
    • Flag (N terminal on backbone)
  • GRB10 GRB-IR, Grb-10, IRBP, MEG1, RSS
    Add to Cart
    38234 pIS1-Actb5UTR-renilla Actb 5'UTR / Renilla (Mus musculus) Mammalian Expression A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pIS1 Actb Actx, E430023M04Rik, beta-actin Add to Cart
    38235 pIS1-Eef25UTR-renilla Eef2 5'UTR / Renilla (Mus musculus) Mammalian Expression, Luciferase A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pIS1 Eef2 Ef-2 Add to Cart
    38236 pIS1-Eef25UTR-TOPmut-renilla Eef2_TOPm_5UTR/Renilla (Mus musculus) Mammalian Expression, Luciferase A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pIS1 Eef2 Ef-2 Add to Cart
    38237 pIS1-Vim5UTR-renilla Vim 5'UTR / Renilla (Mus musculus) Mammalian Expression, Luciferase A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pIS1 Vim Add to Cart
    38238 pIS1-Vim/Actb5UTR-renilla Vim promoter with Actb 5UTR/Renilla (Mus musculus) Mammalian Expression, Luciferase A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pIS1 Vim Actb Actx, E430023M04Rik, beta-actin Add to Cart
    38239 pLJM60-eIF4E eIF4E (Rattus norvegicus) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60 Eif4e Add to Cart
    38240 pCW57.1-4EBP1_4xAla 4EBP1 (Rattus norvegicus) Mammalian Expression, Lentiviral ; Doxycycline inducible A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pCW57.1 Eif4ebp1 PHAS-I Add to Cart
    38241 pLJM60-Ssb Ssb (Homo sapiens) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60 SSB LARP3, La, La/SSB Add to Cart
    38242 pLJM60-Auf1 AUF1 (Homo sapiens) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • AUF1 AUF1A HNRNPD AUF1, AUF1A, HNRPD, P37, hnRNPD0
    Add to Cart
    38243 pLJM60-Tia1 Tia1 (Mus musculus) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Tia1 2310050N03Rik, AI256674, TIA-1, mTIA-1
    Add to Cart
    38244 pLJM60-Tiar Tiar (Mus musculus) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Tial1 5330433G13Rik, AL033329, TIAR, mTIAR
    Add to Cart
    38245 pLJM60-Ptb Ptb (Mus musculus) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Add to Cart
    38246 pLJM60-Cnbp Cnbp (Mus musculus) Mammalian Expression, Lentiviral A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. pLJM60
  • Tag / Fusion Protein
    • FLAG (N terminal on backbone)
  • Cnbp AA408710, Cnbp1, Znf9
    Add to Cart
    42324 pRK5-FLAG-RagB-D163N RagB D163N (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 RRAGB RP11-465E19.1, RAGB, bA465E19.1 Add to Cart
    42325 pRK5-FLAG-RagC-D181N RagC D181N (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 RRAGC GTR2, RAGC, TIB929 Add to Cart
    42326 pRK5-FLAG-HBXIP HBXIP (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 LAMTOR5 HBXIP, XIP Add to Cart
    42327 pRK5-p18G2A-HA p18 G2A (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 LAMTOR1 PP7157, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho Add to Cart
    42328 pRK5-HA-HBXIP HBXIP (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5
  • Tag / Fusion Protein
    • HA (N terminal on insert)
  • LAMTOR5 HBXIP, XIP
    Add to Cart
    42329 pRK5-HA-mp1 mp1 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 LAMTOR3 MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3 Add to Cart
    42330 pRK5-FLAG-p14 p14 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 LAMTOR2 ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, ROBLD3, Ragulator2, p14 Add to Cart
    42331 pRK5-p18-FLAG p18 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5
  • Tag / Fusion Protein
    • Flag (C terminal on insert)
  • LAMTOR1 PP7157, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho
    Add to Cart
    42332 pRK5-FLAG-C7orf59 C7orf59 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5 LAMTOR4 C7orf59 Add to Cart
    42334 N1-p18-EGFP p18 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pEGFP-N1
  • Tag / Fusion Protein
    • EGFP (C terminal on backbone)
  • LAMTOR1 PP7157, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho
    Add to Cart
    42336 pRK5-HA-C7orf59 C7orf59 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5
  • Tag / Fusion Protein
    • HA (N terminal on insert)
  • LAMTOR4 C7orf59
    Add to Cart
    42338 pRK5-p18-HA p18 (Homo sapiens) Mammalian Expression Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. pRK5
  • Tag / Fusion Protein
    • HA (C terminal on insert)
  • LAMTOR1 PP7157, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho
    Add to Cart
    46326 C terminal Flag Mios pRK5 Mios (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 MIOS Add to Cart
    46327 HA Depdc5 pRK5 Depdc5 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 DEPDC5 LL22NC03-113A11.1, DEP.5, FFEVF Add to Cart
    46328 Cterminal HA WDR59 pRK5 WDR59 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 WDR59 FP977 Add to Cart
    46329 Cterminal HA Mios pRK5 Mios (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 MIOS Add to Cart
    46330 HA Nprl3 pRK5 Nprl3 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 NPRL3 Z69666.1-003, C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11 Add to Cart
    46331 HA Seh1L pRK5 Seh1 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 SEH1L SEC13L, SEH1A, SEH1B, Seh1 Add to Cart
    46332 HA Sec13 pRK5 Sec13 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 SEC13 D3S1231E, SEC13L1, SEC13R, npp-20 Add to Cart
    46333 Flag Nprl2 pRK5 Nprl2 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 NPRL2 NPR2, NPR2L, TUSC4 Add to Cart
    46334 Flag WDR24 pRK5 WDR24 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 WDR24 LA16c-313D11.2, C16orf21, JFP7 Add to Cart
    46335 HA WDR24 pRK5 WDR24 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 WDR24 LA16c-313D11.2, C16orf21, JFP7 Add to Cart
    46336 Flag Depdc5 pLJM1 Depdc5 (Homo sapiens) Mammalian Expression, Lentiviral A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pLJM1 DEPDC5 LL22NC03-113A11.1, DEP.5, FFEVF Add to Cart
    46337 Flag WDR24 pLJM1 WDR24 (Homo sapiens) Mammalian Expression, Lentiviral A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pLJM1 WDR24 LA16c-313D11.2, C16orf21, JFP7 Add to Cart
    46338 Flag Nprl2 pLJM1 Nprl2 (Homo sapiens) Mammalian Expression, Lentiviral A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pLJM1 NPRL2 NPR2, NPR2L, TUSC4 Add to Cart
    46340 Flag Depdc5 pRK5 Depdc5 (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 DEPDC5 LL22NC03-113A11.1, DEP.5, FFEVF Add to Cart
    46341 Flag Leucyl tRNA synthetase pRK5 leucyl tRNA synthetase (Homo sapiens) Mammalian Expression A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pRK5 LARS HSPC192, LARS1, LEURS, LEUS, LFIS, LRS, PIG44, RNTLS, hr025Cl Add to Cart
    46380 eGFP Depdc5 pLJM1 Depdc5 (Homo sapiens) Mammalian Expression, Lentiviral A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. pLJM1 DEPDC5 LL22NC03-113A11.1, DEP.5, FFEVF Add to Cart
    48799 pLJM60 mUlk1 (wt) barcoded ULK1 (Mus musculus) Mammalian Expression, Lentiviral mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566. expresses wt Ulk1 pLJM1 Ulk1 AU041434, Unc51.1, mKIAA0722 Add to Cart
    48800 pLJM60-S6K1(T389S) barcoded S6K1 T389S (Rattus norvegicus) Mammalian Expression, Lentiviral mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566. expresses mutant S6K1 pLJM1 Rps6kb1 Add to Cart
    48801 pLJM60-S6K1(wt) barcoded S6K1 (Rattus norvegicus) Mammalian Expression, Lentiviral mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566. expresses wt S6K1 pLJM1 Rps6kb1 Add to Cart
    48805 pRK5 HA-GST-Presc-mAkt1 (wt) Akt1 (Mus musculus) Mammalian Expression mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566. expresses wt Akt1 pRK5 Akt1 Akt, PKB, PKB/Akt, PKBalpha, Rac Add to Cart
    48806 pRK5 HA-GST-Presc-mAkt1 (S473T) Akt1 (Mus musculus) Mammalian Expression mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566. expresses mutant Akt1 pRK5 Akt1 Akt, PKB, PKB/Akt, PKBalpha, Rac Add to Cart
    50661 pCW-Cas9 humanized S. pyogenes Cas9 Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Inducible lentiviral expression of SpCas9 pCW57.1 Add to Cart
    50662 pLX-sgRNA sgAAVS1 Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Lentiviral expression of AAVS1-targeting sgRNA; insert can be replaced with custom sgRNA (see protocol) pLX304 Add to Cart
    51043 Human Lentiviral sgRNA Library - Unknown Function sgRNA library (enriched for genes of unknown function) (Homo sapiens) Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Sub-pool of Sabatini/Lander sgRNA library enriched for gene targets of unknown function. pLX-sgRNA Add to Cart
    51044 Human Lentiviral sgRNA Library - Kinases sgRNA library (enriched for kinase targets) (Homo sapiens) Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets. pLX-sgRNA Add to Cart
    51045 Human Lentiviral sgRNA Library - Ribosomal Proteins sgRNA library (enriched for ribosomal targets) (Homo sapiens) Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Sub-pool of Sabatini/Lander sgRNA library enriched for ribosomal gene targets. pLX-sgRNA Add to Cart
    51046 Human Lentiviral sgRNA Library - Cell Cycle sgRNA library (enriched for cell cycle targets) (Homo sapiens) Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets. pLX-sgRNA Add to Cart
    51047 Human Lentiviral sgRNA Library - Nuclear sgRNA library (enriched for nuclear targets) (Homo sapiens) Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets. pLX-sgRNA Add to Cart
    51048 Human Lentiviral sgRNA Library - Control sgRNA library (enriched for control targets) (Homo sapiens) Mammalian Expression, Lentiviral, CRISPR Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. Sub-pool of Sabatini/Lander sgRNA library enriched for control targets. pLX-sgRNA Add to Cart
    61614 pLJM5-mDPYD dihydropyrimidine dehydrogenase (Mus musculus) Mammalian Expression Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 2014 Aug 28;158(5):1094-109. doi: 10.1016/j.cell.2014.07.032. The mouse Dpyd was used to rescue the human DPYD hairpin affect on EMT pLJM5 Dpyd AI315208, DPD, E330028L06Rik Add to Cart
    61615 pLJM5-I560S-mDPYD Dihydropyrimidine dehydrogenase (Mus musculus) Mammalian Expression Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 2014 Aug 28;158(5):1094-109. doi: 10.1016/j.cell.2014.07.032. The mouse Dpyd was used to rescue the human DPYD hairpin affect on EMT pLJM5 Dpyd AI315208, DPD, E330028L06Rik Add to Cart
    61618 DPYS-FLAG dihydropyrimidinase (Homo sapiens) Mammalian Expression Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 2014 Aug 28;158(5):1094-109. doi: 10.1016/j.cell.2014.07.032. To study the effect of DPYS activity on EMT pLJC2 DPYS DHP, DHPase Add to Cart
    64602 Kras (G12V)-pcw107 KRAS (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64603 Hras (G12V)-pcw107 HRAS (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64604 MEK1 (S218D,S222D)-pcw107V5 MAP2K1 (Mus musculus) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64605 myr-FLAG-PIK3CA-pcw107 PIK3CA (Bos taurus) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tags / Fusion Proteins
    • FLAG (N terminal on insert)
    • myristoylated (N terminal on insert)
  • Add to Cart
    64606 myr-FLAG-AKT1-pcw107 AKT1 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tags / Fusion Proteins
    • FLAG (N terminal on insert)
    • myristoylated (N terminal on insert)
  • Add to Cart
    64607 FLAG-Rheb (Q64L)-pcw107 RHEB (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • FLAG (N terminal on insert)
  • Add to Cart
    64608 IKKalpha (S176E,S180E)-pcw107-V5 CHUK (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64609 FLAG-IKKbeta (S177E,S181E)-pcw107 IKBKB (Other) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • FLAG (N terminal on insert)
  • Add to Cart
    64610 JAK2 (V617F)-pcw107-V5 JAK2 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64611 Stat3 (A662C,N664C,V667L)-pcw107-V5 STAT3 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64612 beta-catenin (S33A, S37A, T41A, S45A)-pcw107 Ctnnb1 (Mus musculus) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64613 beta-catenin (S33A, S37A, T41A, S45A)-pcw107-V5 Ctnnb1 (Mus musculus) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64614 GSK3_ (K85A)-pcw107-V5 GSK3B (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64615 beta-catenin (S33Y)-pcw107 CTNNB1 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64616 beta-catenin (S33Y)-pcw107-V5 CTNNB1 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64619 MEK5 DD(S311D,T315D)-pcw107-V5 MAP2K5 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64621 Notch1 intracellular domain-pcw107 NOTCH1 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64624 p38 WT O/E (MAPK14)-pcw107-V5 MAPK14 (transcript variant 2) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64625 FLAG-MKK6 (S207E,T211E)-pcw107 MAP2K6 (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • FLAG (N terminal on insert)
  • Add to Cart
    64626 Gli2 truncation-pcw107-V5 GLI2 (truncation mutant) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64627 SmoM2 (W535L)-pcw107 SMO (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64628 SmoM2 (W535L)-pcw107-V5 SMO (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64629 TGF_R1 (T204D)-pcw107-V5 TGFBR1 (transcript variant 1) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64630 BCL2-pcw107-V5 BCL2 (transcript variant alpha) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64631 BCL-XL-pcw107-V5 BCL2L1 (transcript variant 1) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64632 Caspase-8 (C360A)-pcw107-V5 CASP8 (transcript variant B) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64633 Caspase-3 (C163A)-pcw107-V5 CASP3 (transcript variant beta) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64634 ERalpha (Y537S mutant)-pcw107-V5 ESR1 (transcript variant 1) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64635 AR-V7-pcw107 AR (transcript variant 1, splice isoform) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64639 HRas (G12V, E37G)-pcw107 HRAS (transcript variant 3) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64640 HRas (G12V, E37G)-pcw107-V5 HRAS (transcript variant 3) (Homo sapiens) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64646 HcRed-pcw107 n/a (Synthetic) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64647 HcRed-pcw107-V5 n/a (Other) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. (control) when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart
    64648 Luciferase-pcw107 n/a (Other) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. (control) when used to produce lentivirus, express physiological levels of insert pcw107 (V5) Add to Cart
    64649 Luciferase-pcw107-V5 n/a (Other) Lentiviral Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. (control) when used to produce lentivirus, express physiological levels of insert pcw107 (V5)
  • Tag / Fusion Protein
    • V5 (C terminal on backbone)
  • Add to Cart