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Linzhao Cheng Lab Plasmids

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Title Authors Publication
Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L Blood. 2002 Jan 15. 99(2):399-408.
Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L Mol Ther. 2003 Jun . 7(6):827-38.
HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI Stem Cells. 2006 Apr . 24(4):876-88.
Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L Stem Cells. 2007 Mar . 25(3):779-89.
Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L Stem Cells. 2008 Aug . 26(8):1998-2005.
The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Jove R, Aplan P, Lin YW, Wertzler K, Reeves R, Elbahlouh O, Kowalski J, Bhattacharya R, Resar LM. Cancer Research 68, 10121, December 15, 2008.
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L Cell Stem Cell. 2009 Jul 2. 5(1):97-110.
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L Cell Res. 2011 Jan 18. ():.
Molecular imaging and stem cell research. Jang YY, Ye Z, Cheng L Mol Imaging. 2011 Apr;10(2):111-22.
Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L Cell Res. 2009 Mar;19(3):370-9.
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Zou J, Mali P, Huang X, Dowey SN, Cheng L Blood. 2011 Oct 27;118(17):4599-608. Epub 2011 Aug 31.
A Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach. Chou BK, Gu H, Gao Y, Dowey SN, Wang Y, Shi J, Li Y, Ye Z, Cheng T, Cheng L Stem Cells Transl Med. 2015 Mar 5. pii: sctm.2014-0214.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
17616EF.GFPEF-1a promoter (Homo sapiens)Mammalian Expression, LentiviralTargeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood. 2002 Jan 15. 99(2):399-408. SIN LV pRLLhPGK.GFP Sin-18 (modified) Add to Cart
17617DR.GFPHLA-DRa promoter (Homo sapiens)Mammalian Expression, LentiviralTargeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood. 2002 Jan 15. 99(2):399-408. SIN LV pRLLhPGK.GFP Sin-18 (modified) HLA-DRA HLA-DRA1 Add to Cart
17618EF.PGK.GFPMammalian Expression, LentiviralLentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther. 2003 Jun . 7(6):827-38. EF.PGK.GFP Add to Cart
17619EF.CMV.RFPMammalian Expression, LentiviralLentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther. 2003 Jun . 7(6):827-38. EF.CMV.RFP Add to Cart
17620EF.delmFasL.CMV.GFPdelFasL (Mus musculus)Mammalian Expression, LentiviralLentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther. 2003 Jun . 7(6):827-38. EF.CMV.GFP Fasl APT1LG1, CD178, CD95-L, CD95L, Fas-L, Faslg, Tnfsf6, Tnlg1a, gld Add to Cart
17622EF.mHES1.CMV.GFPHES1 (Mus musculus)Mammalian Expression, LentiviralHES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells. 2006 Apr . 24(4):876-88. EF.v-CMV.GFP Hes1 Hry, bHLHb39 Add to Cart
17623EF.hICN1.CMV.GFPICN1 (Homo sapiens)Mammalian Expression, LentiviralHES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells. 2006 Apr . 24(4):876-88. EF.v-CMV.GFP NOTCH1 AOS5, AOVD1, TAN1, hN1 Add to Cart
17624EF.hHES1.Ubc.GFPHES1 (Homo sapiens)Mammalian Expression, LentiviralHES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells. 2006 Apr . 24(4):876-88. cFUGW HES1 HES-1, HHL, HRY, bHLHb39 Add to Cart
17625EF.mHES1.Ubc.GFPHES1 (Mus musculus)Mammalian Expression, LentiviralHES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells. 2006 Apr . 24(4):876-88. cFUGW Hes1 Hry, bHLHb39 Add to Cart
17626EF.hICN1.Ubc.GFPICN1 (Homo sapiens)Mammalian Expression, LentiviralHES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells. 2006 Apr . 24(4):876-88. cFUGW NOTCH1 AOS5, AOVD1, TAN1, hN1 Add to Cart
17627Duet011UBC promoter - GFP - PGK promoter - HygroMammalian Expression, LentiviralInducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells. 2007 Mar . 25(3):779-89. Duet011 Add to Cart
17628iDuet011aTetO7 - UBC promoter - GFP - PGK promoter - HygroMammalian Expression, LentiviralInducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells. 2007 Mar . 25(3):779-89. Duet011 Add to Cart
17629iDuet101aTetO7 - EF-1a promoter - GFP - PGK promoter - HygroMammalian Expression, LentiviralInducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells. 2007 Mar . 25(3):779-89. Duet011 Add to Cart
18918tetO7_Ef1a_OCT4OCT4 (Homo sapiens)Mammalian Expression, Lentiviral, Cre/LoxImproved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells. 2008 Aug . 26(8):1998-2005. Duet101 POU5F1 OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 Add to Cart
18919tetO7_Ef1a_SOX2SOX2 (Homo sapiens)Mammalian Expression, Lentiviral, Cre/LoxImproved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells. 2008 Aug . 26(8):1998-2005. Duet101 SOX2 ANOP3, MCOPS3 Add to Cart
18920Ef1a_NANOG_Ires_PuroNANOG (Homo sapiens)Mammalian Expression, Lentiviral, Cre/LoxImproved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells. 2008 Aug . 26(8):1998-2005. EGIP NANOG Add to Cart
18921Ef1a_LIN28_Ires_PuroLIN28 (Homo sapiens)Mammalian Expression, Lentiviral, Cre/LoxImproved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells. 2008 Aug . 26(8):1998-2005. EGIP LIN28A CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A Add to Cart
18922Ef1a_Large T-antigen_Ires_PuroLarge T AntigenMammalian Expression, Lentiviral, Cre/LoxImproved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells. 2008 Aug . 26(8):1998-2005. EGIP SV40gp6 SV40gp6 Add to Cart
24982EF.deltaBHES1.Ubc.GFPHES1 (Homo sapiens)Mammalian Expression, LentiviralHES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells. 2006 Apr . 24(4):876-88. cFUGW HES1 HES-1, HHL, HRY, bHLHb39 Add to Cart
24983EF.STAT3C.Ubc.GFPSTAT3 (Homo sapiens)Mammalian Expression, LentiviralThe high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research 68, 10121, December 15, 2008. Lentiviral expression of constitutively active Stat3 cFUGW STAT3 ADMIO, ADMIO1, APRF, HIES Add to Cart
24984EF.STAT3DN.Ubc.GFPSTAT3 (Homo sapiens)Mammalian Expression, LentiviralThe high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research 68, 10121, December 15, 2008. cFUGW STAT3 ADMIO, ADMIO1, APRF, HIES Add to Cart
26776pEGIP*35GFP*35Mammalian Expression, LentiviralGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. Enables the creation of a chromosomally integrated mutant EGFP target sequence by lentiviral transduction to assess the efficiency of HR-mediated gene targeting pEGIP Add to Cart
26777pEGIPEF1a-GFP-IRES-PuroMammalian Expression, LentiviralGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. Lentiviral vector for stable integration of GFP expression cassette with puromycin selection. Duet011 gfp pCmGFP_001 Add to Cart
26778pPIGA-PHDPGK-Hyg-p(A)Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pCR2.1-TOPO PGK1 YCR012W Add to Cart
26791GFPZFN1.4-B2HGFP-ZFN1Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pcDNA6 Add to Cart
26792GFPZFN2-B2HGFP-ZFN2Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pcDNA6 Add to Cart
26864tGFPTruncated GFP-IRES-PuroBacterial ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pBluescript II KS(+) Add to Cart
28213pEB-C5Oct4, Sox2, Klf4, c-Myc, Lin28 (Mus musculus)Mammalian ExpressionEfficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res. 2011 Jan 18. ():. 5 reprogramming factors (OCT4, SOX2, KLF4, c-MYC and LIN28) are expressed as a single poly-cistronic unit pCEP4 Myc AU016757, Myc2, Niard, Nird, bHLHe39 Add to Cart
28220pEB-TgSV40 large TMammalian ExpressionEfficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res. 2011 Jan 18. ():. pCEP4 Add to Cart
28221pCDNA3.1-NanogNanog (Homo sapiens)Mammalian ExpressionEfficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res. 2011 Jan 18. ():. pcDNA3.1 NANOG Add to Cart
28222pEB-p53shRNAp53 shRNAMammalian ExpressionEfficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res. 2011 Jan 18. ():. pCEP4 Add to Cart
33307Ubc.Luc.IRES.PuroFirefly LuciferaseMammalian Expression, Lentiviral, LuciferaseMolecular imaging and stem cell research. Mol Imaging. 2011 Apr;10(2):111-22. cFUGW Add to Cart
33308cEF.tk-GFPHSV-TK/GFPMammalian Expression, LentiviralSerial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Res. 2009 Mar;19(3):370-9. cFUGW Add to Cart
37486BD2loxP-PGK-Hyg-loxP (Synthetic)iPSC gene targetingSite-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood. 2011 Oct 27;118(17):4599-608. Epub 2011 Aug 31. pCR2.1-TOPO Add to Cart
37797PIGAZFN-L1PIGA zinc finger L1 (Synthetic)Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
37798PIGAZFN-L2PIGA zinc finger L2 (Synthetic)Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
37799PIGAZFN-R1PIGA zinc finger R1 (Synthetic)Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
37800PIGAZFN-R2PIGA zinc finger R2 (Synthetic)Mammalian ExpressionGene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
64120MOSOCT4-2A-SOX2 (Homo sapiens)Mammalian ExpressionA Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach. Stem Cells Transl Med. 2015 Mar 5. pii: sctm.2014-0214. A modified epsiomal (EBNA1/oriP) vector expressing human OCT4 and SOX2 genes pCEP4 POU5F1 OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 SOX2 ANOP3, MCOPS3 Add to Cart
64121MMKMYC-2A-KLF4 (Homo sapiens)Mammalian ExpressionA Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach. Stem Cells Transl Med. 2015 Mar 5. pii: sctm.2014-0214. a modified episomal (EBNA1/OriP) vector expressing human Myc and KLF4 genes pCEP4 MYC MRTL, MYCC, bHLHe39, c-Myc Add to Cart
64122MBXBCL2L1 (Homo sapiens)Mammalian ExpressionA Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach. Stem Cells Transl Med. 2015 Mar 5. pii: sctm.2014-0214. a modified episomal (EBNA1/OriP) vector expressing human BCL2L1 (BCL-xL) gene pCEP4 BCL2L1 BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52 Add to Cart
64123GBXGFP-2A-BCL2L1 (Homo sapiens)Mammalian ExpressionA Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach. Stem Cells Transl Med. 2015 Mar 5. pii: sctm.2014-0214. a modified episomal (EBNA1/OriP) vector expressing human eGFP and BCL-xL genes pCEP4 BCL2 Bcl-2, PPP1R50 Add to Cart