Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at help@addgene.org. Learn more

Linzhao Cheng Lab Plasmids


The Linzhao Cheng Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a non-profit plasmid repository dedicated to improving life science research.

Learn more about research in the Linzhao Cheng Lab.

Addgene Alerts

You must login or create an account to subscribe for Addgene Alerts.

Title Authors Publication
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Zou J, Mali P, Huang X, Dowey SN, Cheng L Blood. 2011 Oct 27;118(17):4599-608. Epub 2011 Aug 31.
Molecular imaging and stem cell research. Jang YY, Ye Z, Cheng L Mol Imaging. 2011 Apr;10(2):111-22.
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L Cell Res. 2011 Jan 18. ():.
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L Cell Stem Cell. 2009 Jul 2. 5(1):97-110.
Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L Cell Res. 2009 Mar;19(3):370-9.
The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Jove R, Aplan P, Lin YW, Wertzler K, Reeves R, Elbahlouh O, Kowalski J, Bhattacharya R, Resar LM. Cancer Research 68, 10121, December 15, 2008.
Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L Stem Cells. 2008 May 29. ():.
Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L Stem Cells. 2007 Mar . 25(3):779-89.
HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI Stem Cells. 2006 Apr . 24(4):876-88.
Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L Mol Ther. 2003 Jun . 7(6):827-38.
Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L Blood. 2002 Jan 15. 99(2):399-408.
Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
EF.GFP EF-1a promoter (Homo sapiens) Mammalian Expression, Lentiviral Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Cui et al Blood. 2002 Jan 15. 99(2):399-408. SIN LV pRLLhPGK.GFP Sin-18 (modified) Add to Cart
DR.GFP HLA-DRa promoter (Homo sapiens) Mammalian Expression, Lentiviral Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Cui et al Blood. 2002 Jan 15. 99(2):399-408. SIN LV pRLLhPGK.GFP Sin-18 (modified) HLA-DRA DASS-397D15.1, HLA-DRA1, MLRW Add to Cart
EF.PGK.GFP Mammalian Expression, Lentiviral Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Yu et al Mol Ther. 2003 Jun . 7(6):827-38. EF.PGK.GFP Add to Cart
EF.CMV.RFP Mammalian Expression, Lentiviral Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Yu et al Mol Ther. 2003 Jun . 7(6):827-38. EF.CMV.RFP Add to Cart
EF.delmFasL.CMV.GFP delFasL (Mus musculus) Mammalian Expression, Lentiviral Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Yu et al Mol Ther. 2003 Jun . 7(6):827-38. EF.CMV.GFP Fasl APT1LG1, CD178, CD95-L, CD95L, Fas-L, Faslg, Tnfsf6, gld Add to Cart
EF.mHES1.CMV.GFP HES1 (Mus musculus) Mammalian Expression, Lentiviral HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu et al Stem Cells. 2006 Apr . 24(4):876-88. EF.v-CMV.GFP Hes1 Hry, bHLHb39 Add to Cart
EF.hICN1.CMV.GFP ICN1 (Homo sapiens) Mammalian Expression, Lentiviral HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu et al Stem Cells. 2006 Apr . 24(4):876-88. EF.v-CMV.GFP NOTCH1 AOS5, AOVD1, TAN1, hN1 Add to Cart
EF.hHES1.Ubc.GFP HES1 (Homo sapiens) Mammalian Expression, Lentiviral HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu et al Stem Cells. 2006 Apr . 24(4):876-88. cFUGW HES1 HES-1, HHL, HRY, bHLHb39 Add to Cart
EF.mHES1.Ubc.GFP HES1 (Mus musculus) Mammalian Expression, Lentiviral HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu et al Stem Cells. 2006 Apr . 24(4):876-88. cFUGW Hes1 Hry, bHLHb39 Add to Cart
EF.hICN1.Ubc.GFP ICN1 (Homo sapiens) Mammalian Expression, Lentiviral HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu et al Stem Cells. 2006 Apr . 24(4):876-88. cFUGW NOTCH1 AOS5, AOVD1, TAN1, hN1 Add to Cart
Duet011 UBC promoter - GFP - PGK promoter - Hygro Mammalian Expression, Lentiviral Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Zhou et al Stem Cells. 2007 Mar . 25(3):779-89. Duet011 Add to Cart
iDuet011a TetO7 - UBC promoter - GFP - PGK promoter - Hygro Mammalian Expression, Lentiviral Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Zhou et al Stem Cells. 2007 Mar . 25(3):779-89. Duet011 Add to Cart
iDuet101a TetO7 - EF-1a promoter - GFP - PGK promoter - Hygro Mammalian Expression, Lentiviral Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Zhou et al Stem Cells. 2007 Mar . 25(3):779-89. Duet011 Add to Cart
tetO7_Ef1a_OCT4 OCT4 (Homo sapiens) Mammalian Expression, Lentiviral, Cre/Lox Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Mali et al Stem Cells. 2008 May 29. ():. Duet101 POU5F1 DADB-104B20.2, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 Add to Cart
tetO7_Ef1a_SOX2 SOX2 (Homo sapiens) Mammalian Expression, Lentiviral, Cre/Lox Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Mali et al Stem Cells. 2008 May 29. ():. Duet101 SOX2 ANOP3, MCOPS3 Add to Cart
Ef1a_NANOG_Ires_Puro NANOG (Homo sapiens) Mammalian Expression, Lentiviral, Cre/Lox Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Mali et al Stem Cells. 2008 May 29. ():. EGIP NANOG Add to Cart
Ef1a_LIN28_Ires_Puro LIN28 (Homo sapiens) Mammalian Expression, Lentiviral, Cre/Lox Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Mali et al Stem Cells. 2008 May 29. ():. EGIP LIN28A CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A Add to Cart
Ef1a_Large T-antigen_Ires_Puro Large T Antigen Mammalian Expression, Lentiviral, Cre/Lox Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Mali et al Stem Cells. 2008 May 29. ():. EGIP SV40gp6 SV40gp6 Add to Cart
EF.deltaBHES1.Ubc.GFP HES1 (Homo sapiens) Mammalian Expression, Lentiviral HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu et al Stem Cells. 2006 Apr . 24(4):876-88. cFUGW HES1 HES-1, HHL, HRY, bHLHb39 Add to Cart
EF.STAT3C.Ubc.GFP STAT3 (Homo sapiens) Mammalian Expression, Lentiviral The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Hillion et al Cancer Research 68, 10121, December 15, 2008. Lentiviral expression of constitutively active Stat3 cFUGW STAT3 ADMIO, APRF, HIES Add to Cart
EF.STAT3DN.Ubc.GFP STAT3 (Homo sapiens) Mammalian Expression, Lentiviral The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Hillion et al Cancer Research 68, 10121, December 15, 2008. cFUGW STAT3 ADMIO, APRF, HIES Add to Cart
pEGIP*35 GFP*35 Mammalian Expression, Lentiviral Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. Enables the creation of a chromosomally integrated mutant EGFP target sequence by lentiviral transduction to assess the efficiency of HR-mediated gene targeting pEGIP Add to Cart
pEGIP EF1a-GFP-IRES-Puro Mammalian Expression, Lentiviral Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. Lentiviral vector for stable integration of GFP expression cassette with puromycin selection. Duet011 gfp pCmGFP_001 Add to Cart
pPIGA-PHD PGK-Hyg-p(A) Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pCR2.1-TOPO PGK1 YCR012W Add to Cart
GFPZFN1.4-B2H GFP-ZFN1 Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pcDNA6 Add to Cart
GFPZFN2-B2H GFP-ZFN2 Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pcDNA6 Add to Cart
tGFP Truncated GFP-IRES-Puro Bacterial Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pBluescript II KS(+) Add to Cart
pEB-C5 Oct4, Sox2, Klf4, c-Myc, Lin28 (Mus musculus) Mammalian Expression Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Chou et al Cell Res. 2011 Jan 18. ():. 5 reprogramming factors (OCT4, SOX2, KLF4, c-MYC and LIN28) are expressed as a single poly-cistronic unit pCEP4 Add to Cart
pEB-Tg SV40 large T Mammalian Expression Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Chou et al Cell Res. 2011 Jan 18. ():. pCEP4 Add to Cart
pCDNA3.1-Nanog Nanog (Homo sapiens) Mammalian Expression Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Chou et al Cell Res. 2011 Jan 18. ():. pcDNA3.1 NANOG Add to Cart
pEB-p53shRNA p53 shRNA Mammalian Expression Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Chou et al Cell Res. 2011 Jan 18. ():. pCEP4 Add to Cart
Ubc.Luc.IRES.Puro Firefly Luciferase Mammalian Expression, Lentiviral, Luciferase Molecular imaging and stem cell research. Jang et al Mol Imaging. 2011 Apr;10(2):111-22. cFUGW Add to Cart
cEF.tk-GFP HSV-TK/GFP Mammalian Expression, Lentiviral Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Pomper et al Cell Res. 2009 Mar;19(3):370-9. cFUGW Add to Cart
BD2 loxP-PGK-Hyg-loxP (Synthetic) iPSC gene targeting Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Zou et al Blood. 2011 Oct 27;118(17):4599-608. Epub 2011 Aug 31. pCR2.1-TOPO Add to Cart
PIGAZFN-L1 PIGA zinc finger L1 (Synthetic) Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
PIGAZFN-L2 PIGA zinc finger L2 (Synthetic) Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
PIGAZFN-R1 PIGA zinc finger R1 (Synthetic) Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart
PIGAZFN-R2 PIGA zinc finger R2 (Synthetic) Mammalian Expression Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Zou et al Cell Stem Cell. 2009 Jul 2. 5(1):97-110. pST1374 Add to Cart