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Peter Hegemann Lab Plasmids


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Title Authors Publication
Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. Stierl M, Stumpf P, Udwari D, Gueta R, Hagedorn R, Losi A, Gartner W, Petereit L, Efetova M, Schwarzel M, Oertner TG, Nagel G, Hegemann P J Biol Chem. 2011 Jan 14. 286(2):1181-8.
Identification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin from Proteomonas sulcata. Wietek J, Broser M, Krause BS, Hegemann P J Biol Chem. 2016 Feb 19;291(8):4121-7. doi: 10.1074/jbc.M115.699637. Epub 2016 Jan 6.
An improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo. Wietek J, Beltramo R, Scanziani M, Hegemann P, Oertner TG, Simon Wiegert J Sci Rep. 2015 Oct 7;5:14807. doi: 10.1038/srep14807.
Conversion of Channelrhodopsin into a Light-Gated Chloride Channel. Wietek J, Wiegert JS, Adeishvili N, Schneider F, Watanabe H, Tsunoda SP, Vogt A, Elstner M, Oertner TG, Hegemann P Science. 2014 Mar 27.
The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Scheib U, Stehfest K, Gee CE, Korschen HG, Fudim R, Oertner TG, Hegemann P Sci Signal. 2015 Aug 11;8(389):rs8. doi: 10.1126/scisignal.aab0611.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
28134pGEM-HE-h_bPAC_cmychumanized photoactivated adenylyl cyclasein vitro transcriptionLight modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. J Biol Chem. 2011 Jan 14. 286(2):1181-8. pGEM-HE Add to Cart
28135pET28a-ec_bPACE.coli adapted photoactivated adenylyl cyclaseBacterial ExpressionLight modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. J Biol Chem. 2011 Jan 14. 286(2):1181-8. pET28a Add to Cart
85461p-mCherry-N1-ChloC ChloC (Synthetic)Mammalian ExpressionConversion of Channelrhodopsin into a Light-Gated Chloride Channel. Science. 2014 Mar 27. Artificial anion conducting ChR2 variant with fast kinetics. Codon optimized for mammalian expression (human/mouse) pEGFP-N1 Add to Cart
85462p-mCherry-N1-slowChloC slowChloC (Synthetic)Mammalian ExpressionConversion of Channelrhodopsin into a Light-Gated Chloride Channel. Science. 2014 Mar 27. Artificial anion conducting ChR2 variant with slow kinetics and high light sensitivity . Codon optimized for mammalian expression (human/mouse) pEGFP-N1 Add to Cart
85463p-mCherry-C1-GtACR2Synthetic construct ACR2 gene (Synthetic)Mammalian ExpressionIdentification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin from Proteomonas sulcata. J Biol Chem. 2016 Feb 19;291(8):4121-7. doi: 10.1074/jbc.M115.699637. Epub 2016 Jan 6. Natural anion conducting Channelrhodopsin with blue absorption. Closing kinetics 60ms. High conductivity. Codon optimized for mammalian expression (human/mouse) pEGFP-C1 Add to Cart
85464p-mCherry-C1-GtACR1Synthetic construct ACR1 gene (Synthetic)Mammalian ExpressionIdentification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin from Proteomonas sulcata. J Biol Chem. 2016 Feb 19;291(8):4121-7. doi: 10.1074/jbc.M115.699637. Epub 2016 Jan 6. Natural anion conducting Channelrhodopsin with cyan absorption. Closing kinetics 140ms. High conductivity. Codon optimized for mammalian expression (human/mouse) pEGFP-C1 Add to Cart
85465p-mCherry-C1-PsACR1Synthetic construct PsChR1 gene (Synthetic)Mammalian ExpressionIdentification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin from Proteomonas sulcata. J Biol Chem. 2016 Feb 19;291(8):4121-7. doi: 10.1074/jbc.M115.699637. Epub 2016 Jan 6. Natural anion conducting Channelrhodopsin with red shifted absorption. Closing kinetics 80ms. Codon optimized for mammalian expression (human/mouse) pEGFP-C1 Add to Cart
85467p-mCherry-N1-iChloCiChloC (Synthetic)Mammalian ExpressionAn improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo. Sci Rep. 2015 Oct 7;5:14807. doi: 10.1038/srep14807. improved slowChloC artificial anion conducting ChR. Codon optimized for mammalian expression (human/mouse) pEGFP-N1 Add to Cart
85468bPAC-mycHis_pGEMBacterial Photoactivated Adenylyl Cyclase (Synthetic)Mammalian ExpressionLight modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. J Biol Chem. 2011 Jan 14. 286(2):1181-8. Expression of photoactivated cyclase bPAC of Beggiatoa sp. pGEM Add to Cart
85469RhGC(BE)_pGEMrhodopsin-guanylyl cyclase (Synthetic)Mammalian ExpressionThe rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Sci Signal. 2015 Aug 11;8(389):rs8. doi: 10.1126/scisignal.aab0611. The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling pGEM Add to Cart