Bob Weinberg Lab Plasmids


The Bob Weinberg Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a non-profit plasmid repository dedicated to improving life science research.

Learn more about research in the Bob Weinberg Lab.

Addgene Alerts

You must login or create an account to subscribe for Addgene Alerts.

Title Authors Publication
Slug and Sox9 cooperatively determine the mammary stem cell state. Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zurrer-Hardi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA Cell. 2012 Mar 2;148(5):1015-28.
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, Teruya-Feldstein J, Bell GW, Weinberg RA Nat Biotechnol. 2010 Apr . 28(4):341-7.
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, Teruya-Feldstein J, Reinhardt F, Onder TT, Valastyan S, Westermann F, Speleman F, Vandesompele J, Weinberg RA Nat Cell Biol. 2010 Mar . 12(3):247-56.
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szasz AM, Wang ZC, Brock JE, Richardson AL, Weinberg RA Cell. 2009 Jun 12. 137(6):1032-46.
Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Shibue T, Weinberg RA Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5.
Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Rai P, Onder TT, Young JJ, McFaline JL, Pang B, Dedon PC, Weinberg RA Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74.
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA Cell. 2008 Jul 11. 134(1):62-73.
The epithelial-mesenchymal transition generates cells with properties of stem cells. Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA Cell. 2008 May 16. 133(4):704-15.
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA Cancer Res. 2008 May 15. 68(10):3645-54.
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Ma L, Teruya-Feldstein J, Weinberg RA Nature. 2007 Oct 11. 449(7163):682-8.
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Mani SA, Yang J, Brooks M, Schwaninger G, Zhou A, Miura N, Kutok JL, Hartwell K, Richardson AL, Weinberg RA Proc Natl Acad Sci U S A. 2007 Jun 12. 104(24):10069-74.
The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA Proc Natl Acad Sci U S A. 2006 Dec 12. 103(50):18969-74.
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Gupta PB, Kuperwasser C, Brunet JP, Ramaswamy S, Kuo WL, Gray JW, Naber SP, Weinberg RA Nat Genet. 2005 Oct . 37(10):1047-54.
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA Cell. 2005 May 6. 121(3):335-48.
Species- and cell type-specific requirements for cellular transformation. Rangarajan A, Hong SJ, Gifford A, Weinberg RA Cancer Cell. 2004 Aug . 6(2):171-83.
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA Cell 2004 Jun 25;117(7):927-39.
Lentivirus-delivered stable gene silencing by RNAi in primary cells. Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD RNA 2003 Apr;9(4):493-501.
Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, DeCaprio JA, Weinberg RA Mol Cell Biol 2002 Apr;22(7):2111-23.
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA Cell 2001 Oct 19;107(2):149-59.
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA Proc Natl Acad Sci U S A. 1999 Oct 26. 96(22):12442-7.
Inhibition of telomerase limits the growth of human cancer cells. Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA Nat Med 1999 Oct;5(10):1164-70.
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8.
Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Liu X, Sun Y, Constantinescu SN, Karam E, Weinberg RA, Lodish HF Proc Natl Acad Sci U S A. 1997 Sep 30. 94(20):10669-74.
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA Cell 1997 Aug 22;90(4):785-95.
Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Geng Y, Eaton EN, Picon M, Roberts JM, Lundberg AS, Gifford A, Sardet C, Weinberg RA Oncogene 1996 Mar 21;12(6):1173-80.
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA Nature. 1993 May 6. 363(6424):45-51.
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, Chen A, Weinberg RA Proc Natl Acad Sci U S A. 1995 Mar 14. 92(6):2403-7.
Growth suppression by p16ink4 requires functional retinoblastoma protein. Medema RH, Herrera RE, Lam F, Weinberg RA Proc Natl Acad Sci U S A. 1995 Jul 3. 92(14):6289-93.
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Bargmann CI, Hung MC, Weinberg RA Cell. 1986 Jun 6. 45(5):649-57.
Expression cloning and characterization of the TGF-beta type III receptor. Wang XF, Lin HY, Ng-Eaton E, Downward J, Lodish HF, Weinberg RA Cell. 1991 Nov 15. 67(4):797-805.
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA Cell. 1992 Sep 18. 70(6):993-1006.
empty vector (unpublished)
pBABE-vectors (unpublished)
Rb-plasmids (unpublished)
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
1761 PBSK HRbc human Rb (Homo sapiens) Bacterial Expression Rb-plasmids (unpublished) pBSK+ RB1 RP11-174I10.1, OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
1762 HRbc-SVE+ human Rb (Homo sapiens) Bacterial Expression Rb-plasmids (unpublished) pBSK+ RB1 RP11-174I10.1, OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
1763 RcCMV/Rb human Rb (Homo sapiens) Mammalian Expression Rb-plasmids (unpublished) Rc/CMV RB1 RP11-174I10.1, OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
1768 pBabe-puro Ras V12 ras V12 (Homo sapiens) Mammalian Expression, Retroviral pBABE-vectors (unpublished) pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
1769 pYESir2-puro Sir2 (Homo sapiens) Mammalian Expression, Retroviral Vaziri et al Cell 2001 Oct 19;107(2):149-59. pBABE-puro SIRT1 RP11-57G10.3, SIR2L1
1770 pYESir2HY-puro Sir2 (Homo sapiens) Mammalian Expression, Retroviral Vaziri et al Cell 2001 Oct 19;107(2):149-59. pBABE-puro SIRT1 RP11-57G10.3, SIR2L1
1771 pBABE-puro-hTERT hTERT (Homo sapiens) Mammalian Expression, Retroviral Counter et al Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. Retroviral expression of hTERT. Used to create immortalized cell lines. pBABE-puro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1772 pBABE-puro-hTERT-HA hTERT (Homo sapiens) Mammalian Expression, Retroviral Counter et al Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. pBABE-puro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1773 pBABE-hygro-hTERT hTERT (Homo sapiens) Mammalian Expression, Retroviral Counter et al Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. Retroviral expression of hTERT. Used to create immortalized cell lines. pBABE-hygro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1774 pBABE-neo-hTERT hTERT (Homo sapiens) Mammalian Expression, Retroviral Counter et al Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. Retroviral expression of hTERT. Used to create immortalized cell lines. pBABE-neo TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1775 pBABE-puro-DN-hTERT hTERT (Homo sapiens) Mammalian Expression, Retroviral Hahn et al Nat Med 1999 Oct;5(10):1164-70. pBABE-puro TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1778 pBABE-zeo largeTgenomic large T and small T antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp6 SV40gp6
1779 pBABE-zeo largeTcDNA large T antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp6 SV40gp6
1780 pBABE-neo largeTcDNA large T antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. Retroviral expression of Large T Antigen. Used to create immortalized cell lines. pBABE-neo SV40gp6 SV40gp6
1781 pCI neo-hEST2 hTERT (Homo sapiens) Mammalian Expression Meyerson et al Cell 1997 Aug 22;90(4):785-95. pCI neo TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1782 pCI neo-hEST2-HA hTERT (Homo sapiens) Mammalian Expression Meyerson et al Cell 1997 Aug 22;90(4):785-95. pCI neo TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
1783 pBABE-puro-mTwist Twist (Mus musculus) Mammalian Expression, Retroviral Yang et al Cell 2004 Jun 25;117(7):927-39. pBABE-puro Twist1 AA960487, M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt
1784 Twist-siRNA3 siTwist (Mus musculus) Mammalian Expression Yang et al Cell 2004 Jun 25;117(7):927-39. pSP-108 Twist1 AA960487, M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt
8449 pUMVC Mammalian Expression, Retroviral Stewart et al RNA 2003 Apr;9(4):493-501. Packaging plasmid for producing MuLV retroviral particles. Use in conjunction with an envelope plasmid such as pCMV-VSV-G. pUMVC
8450 Retrohair Mammalian Expression, Retroviral, RNAi Stewart et al RNA 2003 Apr;9(4):493-501. pBABE
8451 Lentihair s1GFP siRNA against GFP Mammalian Expression, Lentiviral, RNAi Stewart et al RNA 2003 Apr;9(4):493-501. pLentihair
8452 pMKO.1 puro Mammalian Expression, Retroviral, RNAi Stewart et al RNA 2003 Apr;9(4):493-501. pMSCV
8453 pLKO.1 puro Mammalian Expression, Lentiviral, RNAi Stewart et al RNA 2003 Apr;9(4):493-501. 3rd gen lentiviral backbone for cloning and expression of new shRNA sequences. Uses puromycin for selection. pLKO.1
8454 pCMV-VSV-G Mammalian Expression Stewart et al RNA 2003 Apr;9(4):493-501. Envelope protein for producing lentiviral and MuLV retroviral particles. Use in conjunction with a packaging vector such as pCMV-dR8.2 dvpr (lentiviral) or pUMVC (MuLV retroviral). na
8455 pCMV-dR8.2 dvpr Mammalian Expression, Lentiviral Stewart et al RNA 2003 Apr;9(4):493-501. 2nd generation lentiviral packaging plasmid. Can be used with 2nd and 3rd generation transfer vectors. Use in conjunction with an envelope plasmid such as pCMV-VSV-G. na
8456 Twist-siRNA5 siTwist (Mus musculus) Mammalian Expression Yang et al Cell 2004 Jun 25;117(7):927-39. pSP-108 Twist1 AA960487, M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt
8457 Twist-siRNA7 siTwist (Mus musculus) Mammalian Expression Yang et al Cell 2004 Jun 25;117(7):927-39. pSP-108 Twist1 AA960487, M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt
8458 10-4 cyclin E promoter human cyclin E promoter (Homo sapiens) Mammalian Expression, Luciferase Geng et al Oncogene 1996 Mar 21;12(6):1173-80. pGL-2 CCNE1 CCNE
8460 EE-mut SV40 luc human cyclin E promoter fragment, mutant (Homo sapiens) Mammalian Expression, Luciferase Geng et al Oncogene 1996 Mar 21;12(6):1173-80. pGL2-Promoter CCNE1 CCNE
8581 pBABE-neo largeTcDNA K1 large T antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-neo SV40gp6 SV40gp6
8582 pBABE-neo largeTcDNA delta434-444 large T antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-neo SV40gp6 SV40gp6
8583 pBABE-zeo smallT SV40 small T Antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7
8959 Rc/CMV cyclin A cyclin A (Homo sapiens) Mammalian Expression Hinds et al Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNA2 CCN1, CCNA
8961 Rc/CMV cyclin C cyclin C (Homo sapiens) Mammalian Expression Hinds et al Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNC CycC
8962 Rc/CMV cyclin D1 cyclin D1 (Homo sapiens) Mammalian Expression Hinds et al Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCND1 BCL1, D11S287E, PRAD1, U21B31
8963 Rc/CMV cyclin E cyclin E (Homo sapiens) Mammalian Expression Hinds et al Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNE1 CCNE
9048 pBABE-neo largeTcDNA H42Q large T antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-neo SV40gp6 SV40gp6
9058 pBABE-hygro p53 DD p53 DD (Mus musculus) Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE hygro Trp53 RP23-56I20.1, Tp53, bbl, bfy, bhy, p44, p53
9059 pMIG small T SV40 small T Antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7
9060 pMIG small T C97S E102Q SV40 small T Antigen 97, 102 Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7
9061 pMIG small T 110 SV40 small T Antigen 110 Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7
9062 pMIG small T H42Q SV40 small T Antigen H42Q Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7
9063 pBABE-zeo small T 110 SV40 small T Antigen 110 Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7
9064 pBABE-zeo small T C97S E102Q SV40 small T Antigen 97, 102 Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7
9065 pBABE-zeo small T H42Q SV40 small T Antigen Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7
10690 pBABE-zeo small T 88 SV40 small T Antigen 88 Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-zeo SV40gp7 SV40gp7
10691 pMIG small T 88 SV40 small T Antigen 88 Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pMIG SV40gp7 SV40gp7
10900 GFP-siRNA control siGFP Mammalian Expression Yang et al Cell 2004 Jun 25;117(7):927-39. pSP-108
10901 pBABE-puro HGF HGF (Homo sapiens) Mammalian Expression, Retroviral Gupta et al Nat Genet. 2005 Oct . 37(10):1047-54. pBABE-puro HGF DFNB39, F-TCF, HGFB, HPTA, SF
10902 pBABE-puro TPR-Met TPR-Met (Homo sapiens) Mammalian Expression, Retroviral Gupta et al Nat Genet. 2005 Oct . 37(10):1047-54. pBABE-puro MET AUTS9, HGFR, RCCP2, c-Met TPR
10903 siSlug1 siSlug (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Gupta et al Nat Genet. 2005 Oct . 37(10):1047-54. pLKO.1 SNAI2 SLUG, SLUGH1, SNAIL2, WS2D
10904 siSlug2 siSlug (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Gupta et al Nat Genet. 2005 Oct . 37(10):1047-54. pLKO.1 SNAI2 SLUG, SLUGH1, SNAIL2, WS2D
10905 siSlug3 siSlug (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Gupta et al Nat Genet. 2005 Oct . 37(10):1047-54. pLKO.1 SNAI2 SLUG, SLUGH1, SNAIL2, WS2D
10908 pCI-Neo HA-hSnoN SnoN (Homo sapiens) Mammalian Expression Sun et al Proc Natl Acad Sci U S A. 1999 Oct 26. 96(22):12442-7. pCI-neo SKIL SNO, SnoA, SnoI, SnoN
10910 pCI-Neo HA-hSki Ski (Homo sapiens) Mammalian Expression Sun et al Proc Natl Acad Sci U S A. 1999 Oct 26. 96(22):12442-7. pCI-neo SKI SGS, SKV
10911 Rc/CMV cyclin B2 cyclin B2 (Homo sapiens) Mammalian Expression Hinds et al Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCNB2 HsT17299
10912 Rc/CMV cyclin D3 cyclin D3 (Homo sapiens) Mammalian Expression Hinds et al Cell. 1992 Sep 18. 70(6):993-1006. pRc/CMV CCND3 RP5-973N23.3
10913 pcDNA type III TGF beta receptor (R3-OFF) R3-OFF (Rattus norvegicus) Mammalian Expression Wang et al Cell. 1991 Nov 15. 67(4):797-805. pcDNAI neo Tgfbr3 betaglycan
10914 pcDNA3-E2F4 E2F4 (Homo sapiens) Mammalian Expression Sardet et al Proc Natl Acad Sci U S A. 1995 Mar 14. 92(6):2403-7. pcDNA3 E2F4 E2F-4
10916 pCMV p16 INK4A p16 INK4 (Homo sapiens) Mammalian Expression Medema et al Proc Natl Acad Sci U S A. 1995 Jul 3. 92(14):6289-93. pcDNA3 CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16
10917 pSV2 neuN neuN (Rattus norvegicus) Mammalian Expression Bargmann et al Cell. 1986 Jun 6. 45(5):649-57. pSV2 neo Erbb2
10918 pSV2 neuNT neuNT (Rattus norvegicus) Mammalian Expression Bargmann et al Cell. 1986 Jun 6. 45(5):649-57. pSV2 neo Erbb2
10919 pSV2 neuT neuT (Rattus norvegicus) Mammalian Expression Bargmann et al Cell. 1986 Jun 6. 45(5):649-57. pSV2-dhfr Erbb2
10920 pEXL flag Smad3 Smad3 (Homo sapiens) Mammalian Expression Liu et al Proc Natl Acad Sci U S A. 1997 Sep 30. 94(20):10669-74. pEXL (derived from pEGFP-N1) SMAD3 HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3
11254 pBABE-hygro CDK4 R24C CDK4 (Homo sapiens) Mammalian Expression, Retroviral Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23. pBABE-hygro CDK4 CMM3, PSK-J3
12269 pWZL Blast GFP EGFP Mammalian Expression, Retroviral Orimo et al Cell. 2005 May 6. 121(3):335-48. pWZL Blast
12270 pBABE puro SDF-1 alpha SDF-1 alpha (Homo sapiens) Mammalian Expression, Retroviral Orimo et al Cell. 2005 May 6. 121(3):335-48. pBABE-puro CXCL12 IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1
12271 pLKO.1 puro CXCR4 siRNA-1 CXCR4 siRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Orimo et al Cell. 2005 May 6. 121(3):335-48. pLKO.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
12272 pLKO.1 puro CXCR4 siRNA-2 CXCR4 siRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Orimo et al Cell. 2005 May 6. 121(3):335-48. pLKO.1 CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
12273 pLKO.1 puro GFP siRNA GFP siRNA Mammalian Expression, Lentiviral, RNAi Orimo et al Cell. 2005 May 6. 121(3):335-48. pLKO.1
12274 pBabe puro H-Ras G12V T35S H-Ras G12V T35S (Homo sapiens) Mammalian Expression, Retroviral Rangarajan et al Cancer Cell. 2004 Aug . 6(2):171-83. pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
12275 pBabe puro H-Ras G12V E37G H-Ras G12V E37G (Homo sapiens) Mammalian Expression, Retroviral Rangarajan et al Cancer Cell. 2004 Aug . 6(2):171-83. pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
12276 pBabe puro H-Ras G12V Y40C H-Ras G12V Y40C (Homo sapiens) Mammalian Expression, Retroviral Rangarajan et al Cancer Cell. 2004 Aug . 6(2):171-83. pBABE-puro HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
12277 pWZL Blast H-Ras G12V E37G H-Ras G12V E37G (Homo sapiens) Mammalian Expression, Retroviral Rangarajan et al Cancer Cell. 2004 Aug . 6(2):171-83. pWZL Blast HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
12278 pWZL Blast H-Ras G12V T35S H-Ras G12V T35S (Homo sapiens) Mammalian Expression, Retroviral Rangarajan et al Cancer Cell. 2004 Aug . 6(2):171-83. pWZL Blast HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
12279 pWZL Blast H-Ras G12V Y40C H-Ras G12V Y40C (Homo sapiens) Mammalian Expression, Retroviral Rangarajan et al Cancer Cell. 2004 Aug . 6(2):171-83. pWZL Blast HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
14095 pWZL blast goosecoid goosecoid (Mus musculus) Mammalian Expression, Retroviral Hartwell et al Proc Natl Acad Sci U S A. 2006 Dec 12. 103(50):18969-74. pWZL Blast Gsc
14096 pWZL blast HA goosecoid goosecoid (Mus musculus) Mammalian Expression, Retroviral Hartwell et al Proc Natl Acad Sci U S A. 2006 Dec 12. 103(50):18969-74. pWZL Blast Gsc
15535 pBabe human FOXC2 FOXC2 (Homo sapiens) Mammalian Expression, Retroviral Mani et al Proc Natl Acad Sci U S A. 2007 Jun 12. 104(24):10069-74. pBabe puro FOXC2 FKHL14, LD, MFH-1, MFH1
16070 MDH1-PGK-GFP microRNA-10b microRNA-10b (Homo sapiens) Mammalian Expression, Retroviral, RNAi Ma et al Nature. 2007 Oct 11. 449(7163):682-8. MDH1-PGK-GFP 2.0 MIR10B MIRN10B, hsa-mir-10b, miRNA10B, mir-10b
18798 pWZL Blast Snail ER snail (Homo sapiens) Mammalian Expression, Retroviral Mani et al Cell. 2008 May 16. 133(4):704-15. pWZL-Blast SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
18799 pWZL Blast Twist ER twist (Mus musculus) Mammalian Expression, Retroviral Mani et al Cell. 2008 May 16. 133(4):704-15. pWZL-Blast Twist1 AA960487, M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt
18800 pWZL Blast DN E-cadherin Dom neg E-cadherin (Mus musculus) Mammalian Expression, Retroviral Onder et al Cancer Res. 2008 May 15. 68(10):3645-54. pWZL-Blast Cdh1 AA960649, E-cad, Ecad, L-CAM, UVO, Um
18801 pLKO.1 puro shRNA E-cadherin E-cadherin shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Onder et al Cancer Res. 2008 May 15. 68(10):3645-54. pLKO.1 puro CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO
18802 pLKO.1 hygro shRNA E-cadherin E-cadherin shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Onder et al Cancer Res. 2008 May 15. 68(10):3645-54. pLKO.1 hygro CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO
18803 pLKO.1 puro shRNA beta-catenin b-catenin shRNA (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Onder et al Cancer Res. 2008 May 15. 68(10):3645-54. 3rd gen lentiviral vector for knocking down beta-catenin gene expression pLKO.1 puro CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo
18804 pWZL Blast mouse E-cadherin E-cadherin (Mus musculus) Mammalian Expression, Retroviral Onder et al Cancer Res. 2008 May 15. 68(10):3645-54. pWZL-Blast Cdh1 AA960649, E-cad, Ecad, L-CAM, UVO, Um
19116 pMIR-D10 mutUTR HOXD10 mut 3' UTR (Homo sapiens) Mammalian Expression Ma et al Nature. 2007 Oct 11. 449(7163):682-8. pMIR-report HOXD10 HOX4, HOX4D, HOX4E, Hox-4.4
19117 pMIR-D10 UTR HOXD10 3' UTR (Homo sapiens) Mammalian Expression Ma et al Nature. 2007 Oct 11. 449(7163):682-8. pMIR-report HOXD10 HOX4, HOX4D, HOX4E, Hox-4.4
19118 pMIR-10b microRNA 10b (Homo sapiens) Mammalian Expression Ma et al Nature. 2007 Oct 11. 449(7163):682-8. pMIR-report MIR10B MIRN10B, hsa-mir-10b, miRNA10B, mir-10b
19119 shp53 pLKO.1 puro small hairpin RNA against tumor protein p53 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Godar et al Cell. 2008 Jul 11. 134(1):62-73. 3rd gen lentiviral vector for knocking down p53 gene expression pLKO.1 puro TP53 BCC7, LFS1, P53, TRP53
19120 shp63alpha pLKO.1 puro small hairpin RNA against tumor protein p63 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Godar et al Cell. 2008 Jul 11. 134(1):62-73. pLKO.1 puro TP63 AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
19122 CD44P pGL3 CD44 promoter (Homo sapiens) Non viral cloning vector Godar et al Cell. 2008 Jul 11. 134(1):62-73. pGL3-Basic CD44 AL133330.1, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
19123 shCD44-2 pRRL small hairpin RNA against CD44 (Homo sapiens) Mammalian Expression, Lentiviral Godar et al Cell. 2008 Jul 11. 134(1):62-73. pRRL-U6-siluc-cppt-hPGKGFPSIN CD44 AL133330.1, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
19124 shCD44-3 pRRL small hairpin RNA against CD44 (Homo sapiens) Mammalian Expression, Lentiviral Godar et al Cell. 2008 Jul 11. 134(1):62-73. pRRL-U6-siluc-cppt-hPGKGFPSIN CD44 AL133330.1, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
19125 shLuc pRRL control shRNA Mammalian Expression, Lentiviral Godar et al Cell. 2008 Jul 11. 134(1):62-73. pRRL-U6-siluc-cppt-hPGKGFPSIN
19126 CD44S pWZL-Blast CD44 standard (Homo sapiens) Mammalian Expression, Retroviral Godar et al Cell. 2008 Jul 11. 134(1):62-73. pWZL Blast CD44 AL133330.1, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
19127 CD44S pBabe-puro CD44 standard (Homo sapiens) Mammalian Expression, Retroviral Godar et al Cell. 2008 Jul 11. 134(1):62-73. pBABE-puro CD44 AL133330.1, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
21295 pBabe puro MTH1 MTH1 (Homo sapiens) Mammalian Expression, Retroviral Rai et al Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pBABE-puro NUDT1 MTH1
21296 pBabe hygro MTH1 MTH1 (Homo sapiens) Mammalian Expression, Retroviral Rai et al Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pBABE-hygro NUDT1 MTH1
21297 pLKO.1 shMTH1-1 shMTH1-1 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Rai et al Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pLKO.1 puro NUDT1 MTH1
21298 pLKO.1 shMTH1-2 shMTH1-2 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Rai et al Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):169-74. pLKO.1 puro NUDT1 MTH1
22693 pISI-mmP16 3' UTR mmP16 3'UTR Mammalian Expression Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
22694 pBABE-puro-mIR-31 sponge miR-31 (Homo sapiens) Mammalian Expression, Retroviral Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. Stable suppression of miR-31 function pBABE-puro MIR31 MIRN31, hsa-mir-31, miR-31
22744 pBp-Control Sponge (CXCR4 sponge) CXCR4 control sponge Mammalian Expression, Retroviral Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pBABE-puro
23347 pBabe puro Snail Snail (Homo sapiens) Mammalian Expression, Retroviral Mani et al Proc Natl Acad Sci U S A. 2007 Jun 12. 104(24):10069-74. pBabe puro SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
24150 pLKO.1 hygro Mammalian Expression, Lentiviral, RNAi empty vector (unpublished) 3rd gen lentiviral backbone for cloning and expression of new shRNA sequences. Uses hygromycin for selection. pLKO.1 - TRC cloning vector
25021 pIS1-miR-31 site synthetic miR-31 site Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
25023 pIS1-mutant Fzd3 3'UTR mutant Fzd3 3'UTR Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
25024 pIS1-wt Fzd3 3'UTR wt Fzd3 3'UTR Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
25025 CMV-miR-31 sponge CMV-miR-31 sponge Mammalian Expression Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pcDNA5-CMV-d2eGFP
25026 pIS1-miR-126 site synthetic miR-126 site Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
25027 pIS1-miR-206 site synthetic miR-206 site Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
25028 pIS1-miR-335 site synthetic miR-335 site Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1
25036 MDH1-PGK-GFP-miR9 mir-9-3 (Homo sapiens) Mammalian Expression, Retroviral, RNAi Ma et al Nat Cell Biol. 2010 Mar . 12(3):247-56. MDH1-PGK-GFP 2.0 MIR9-3 MIRN9-3, miRNA9-3, hsa-mir-9-3
25037 pMIR-9 miR-9 binding site (Homo sapiens) Mammalian Expression, Luciferase Ma et al Nat Cell Biol. 2010 Mar . 12(3):247-56. pMIR-report
25038 pMIR-CDH1 wtUTR CDH1 3'UTR (Homo sapiens) Mammalian Expression, Luciferase Ma et al Nat Cell Biol. 2010 Mar . 12(3):247-56. pMIR-report CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO
25039 pMIR-CDH1 mutUTR CDH1 mutant 3'UTR (Homo sapiens) Mammalian Expression, Luciferase Ma et al Nat Cell Biol. 2010 Mar . 12(3):247-56. pMIR-report CDH1 Arc-1, CD324, CDHE, ECAD, LCAM, UVO
25040 pBabe-puro-miR-9 sponge miR-9 sponge Mammalian Expression, Retroviral Ma et al Nat Cell Biol. 2010 Mar . 12(3):247-56. pBabe-puro
25043 pBabe-puro-miR-10b sponge miR-10b sponge Mammalian Expression, Retroviral Ma et al Nat Biotechnol. 2010 Apr . 28(4):341-7. pBabe-puro
26085 pSVE Grb2 myc 49L Grb2 P49L (Homo sapiens) Mammalian Expression Egan et al Nature. 1993 May 6. 363(6424):45-51. pSVE GRB2 ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
26087 pSVE Grb2 myc 49L/203R Grb2 49L/203R (Homo sapiens) Mammalian Expression Egan et al Nature. 1993 May 6. 363(6424):45-51. pSVE GRB2 ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
26088 pBabe-puro-mIR-31 miR-31 (Homo sapiens) Mammalian Expression, Retroviral Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pBABE-puro MIR31 MIRN31, hsa-mir-31, miR-31
26089 pIS1-wt RhoA 3'UTR wt RhoA 3'UTR (Homo sapiens) Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1 RHOA ARH12, ARHA, RHO12, RHOH12
26090 pIS1-mutant RhoA 3'UTR mutant RhoA 3'UTR (Homo sapiens) Mammalian Expression, Luciferase Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46. pIS1 RHOA ARH12, ARHA, RHO12, RHOH12
36976 pTK-Snail Snail (Mus musculus) Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pTK380 (tetracycline inducible) Snai1 RP23-118A2.5, AI194338, Sna, Sna1, Snail, Snail1
36977 pTK-Twist Twist Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pTK380 (tetracycline inducible) Twist1 AA960487, M-Twist, Pde, Ska10, Ska<m10Jus>, Twist, bHLHa38, pdt
36978 FUW-Sox10 Sox10 (Homo sapiens) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. FUW-LPT2 (tetracycline-inducible) SOX10 RP5-1039K5.9, DOM, PCWH, WS2E, WS4, WS4C
36979 pWPXL-Sox9 Sox9 (Mus musculus) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pWPXL Sox9 RP23-36D5.1, 2010306G03Rik, AV220920, mKIAA4243
36980 pWPXL-c-Myc c-Myc (Mus musculus) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pWPXL Myc AU016757, Myc2, Niard, Nird, bHLHe39
36981 pWPXL-Klf4 Klf4 (Mus musculus) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pWPXL Klf4 RP23-322L22.2, EZF, Gklf, Zie
36983 pWPXL-Hes1 Hes1 (Mus musculus) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pWPXL Hes1 Hry, bHLHb39
36984 pWPXL-Sox4 Sox4 (Homo sapiens) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pWPXL SOX4 EVI16
36985 pLV-beta-catenin deltaN90 beta-catenin deltaN90 (Homo sapiens) Mammalian Expression, Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLV-IRES-neo CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo
36986 pTK-Slug slug (Mus musculus) Lentiviral Guo et al Cell. 2012 Mar 2;148(5):1015-28. pTK380 (tetracycline inducible) Snai2 Slug, Slugh, Snail2
37007 pLKO.1-sh-mSox10-2 sh-mSox10-2 (Mus musculus) Mammalian Expression, Lentiviral, RNAi Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453) Sox10 Dom, Sox21
37013 pLV-neo-CD2-FAK CD2-FAK (Homo sapiens) Mammalian Expression, Lentiviral Shibue et al Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5. pLV-IRES-neo CD2 RP4-655N15.2, LFA-2, SRBC, T11 PTK2 FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
37015 pLKO-puro-sh-mFAK C sh-mFAK C (Mus musculus) Mammalian Expression, Lentiviral, RNAi Shibue et al Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5. pLKO.1 puro (Addgene plasmid 8453) Ptk2 FAK, FRNK, Fadk, mKIAA4203, p125FAK
37018 pLKO-puro-sh-mFAK B sh-mFAK B (Mus musculus) Mammalian Expression, Lentiviral, RNAi Shibue et al Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. Epub 2009 Jun 5. pLKO.1 puro (Addgene plasmid 8453) Ptk2 FAK, FRNK, Fadk, mKIAA4203, p125FAK
40644 pLKO.1-sh-hSOX9-1 sh-hSOX9-1 (Homo sapiens) Mammalian Expression, Lentiviral, RNAi Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453)
40645 pLKO.1-sh-mSOX9-2 sh-mSOX9-2 (Mus musculus) Mammalian Expression, Lentiviral, RNAi Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453)
40646 pLKO.1-sh-mSOX9-5 sh-mSOX9-5 (Mus musculus) Mammalian Expression, Lentiviral, RNAi Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453)
40647 pLKO.1-sh-mSlug-3 sh-mSlug-3 (Mus musculus) Mammalian Expression, Lentiviral, RNAi Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453)
40648 pLKO.1-sh-mSlug-4 sh-mSlug-4 (Mus musculus) Mammalian Expression, Lentiviral, RNAi Guo et al Cell. 2012 Mar 2;148(5):1015-28. pLKO.1 puro (Addgene plasmid 8453)