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Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM
Science. 2015 Jan 9;347(6218):188-94. doi: 10.1126/science.1257132. Epub 2015 Jan 7.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
71855pRK5-FLAG-SLC38A9.1overexpression
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71858pLJM60-FLAG-SLC38A9.1lentiviral stable expression
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71861pLJM60-FLAG-SLC38A9.1 (delta110)lentiviral stable expression
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71862pLJM60-FLAG-SLC38A9.1 (1-119aa)lentiviral stable expression
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71863pLJM60-FLAG-SLC38A9.1 H60Alentiviral stable expression
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71864pLJM60-FLAG-SLC38A9.1 I68Alentiviral stable expression
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71865pLJM60-FLAG-SLC38A9.1 Y71Alentiviral stable expression
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71866pLJM60-FLAG-SLC38A9.1 L74Alentiviral stable expression
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71867pLJM60-FLAG-SLC38A9.1 P90Alentiviral stable expression
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71868pRK5-LAMP1-FLAGoverexpression
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71869pRK5-HA-SLC38A9.1overexpression
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Recombinant Antibodies from Article