Addgene: Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3.

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Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3.
Kazi JU, Sun J, Phung B, Zadjali F, Flores-Morales A, Ronnstrand L
J Biol Chem. 2012 Oct 19;287(43):36509-17. doi: 10.1074/jbc.M112.376111. Epub 2012 Sep 5. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
74496	pMSCV-SOCS6-WT	Overexpression of SOCS6 in mammalian cells
74497	pcDNA3-Flt3-Y591F/Y919F	Overexpression of FLT3 Y591F/Y919F mutant in mammalian cells
74498	pMSCV-Flt3-Y591F/Y919F	Retroviral expression of FLT3 Y591F/Y919F
74499	pMSCV-Flt3-ITD-Y591F/Y919F	Retroviral expression of FLT3 ITD-Y591F/Y919F

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