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PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis.
Lee MS, Jeong MH, Lee HW, Han HJ, Ko A, Hewitt SM, Kim JH, Chun KH, Chung JY, Lee C, Cho H, Song J
Nat Commun. 2015 Jul 17;6:7769. doi: 10.1038/ncomms8769. PubMed Article

Plasmids from Article

ID Plasmid Purpose
78774pcDNA3-FLAG MKRN1 S109ATo overexpress MKRN1 S109A in Mammalian Cells
78775pcDNA3-FLAG MKRN1 S109DTo overexpress MKRN1 S109D in Mammalian Cells
78776pcDNA3-HA PTENTo overexpress PTEN in Mammalian Cells
78777pcDNA3-FLAG PTENTo overexpress PTEN in Mammalian Cells
78778pcDNA3.1-HA AKT1To overexpress AKT1 in Mammalian Cells

Antibodies from Article