Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures.
Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, Pillai MM
Oncogene. 2016 Aug 15. doi: 10.1038/onc.2016.279. PubMed Article
Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, Pillai MM
Oncogene. 2016 Aug 15. doi: 10.1038/onc.2016.279. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
82576 | pCDNA3.1-FLAG-SF3B1-WT | Expresses a codon-optimized ORF of human SF3B1 (wild-type) |
82577 | pCDNA3.1-FLAG-hSF3B1-K700E | Expresses a codon-optimized ORF of human SF3B1 ( K700E mutant) |