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An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3.
Bose K, Pop C, Feeney B, Clark AC
Biochemistry. 2003 Oct 28;42(42):12298-310.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
90090pET21b-Caspase-3(D3A: D175A D28A D9A)Expresses caspase 3 D3A mutant (D175A D28A D9A) in bacterial cells

Antibodies from Article