Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.
Mayerle M, Raghavan M, Ledoux S, Price A, Stepankiw N, Hadjivassiliou H, Moehle EA, Mendoza SD, Pleiss JA, Guthrie C, Abelson J
Proc Natl Acad Sci U S A. 2017 Apr 17. pii: 201701462. doi: 10.1073/pnas.1701462114. PubMed Article
Mayerle M, Raghavan M, Ledoux S, Price A, Stepankiw N, Hadjivassiliou H, Moehle EA, Mendoza SD, Pleiss JA, Guthrie C, Abelson J
Proc Natl Acad Sci U S A. 2017 Apr 17. pii: 201701462. doi: 10.1073/pnas.1701462114. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 90964 | pRS313-PRP8 | yeast vector |
| 90966 | pRS313 - prp8 V1860N | yeast vector |
| 90967 | pRS313 - prp8 V1862D | yeast vector |
| 90968 | pRS313 - prp8 T1865K | yeast vector |
| 90969 | pRS313 - prp8 A1871E | yeast vector |
| 90970 | pRS313 - prp8 T1872E | yeast vector |
| 90971 | pRS313 - prp8 T1861P | yeast vector |
| 90972 | pRS313 - prp8 V1862Y | yeast vector |
| 90973 | pRS313 - prp8 H1863E | yeast vector |
| 90974 | pRS313 - prp8 K1864E | yeast vector |
| 90975 | pRS313 - prp8 N1869D | yeast vector |
| 90976 | pRS313 - prp8 V1870N | yeast vector |
| 90977 | pRS313 - prp8 I1875T | yeast vector |