A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.
Rogers ZN, McFarland CD, Winters IP, Naranjo S, Chuang CH, Petrov D, Winslow MM
Nat Methods. 2017 May 22. doi: 10.1038/nmeth.4297. PubMed Article
Rogers ZN, McFarland CD, Winters IP, Naranjo S, Chuang CH, Petrov D, Winslow MM
Nat Methods. 2017 May 22. doi: 10.1038/nmeth.4297. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 89641 | Lenti-sgApc/Cre | Expresses an Apc-targeting gRNA and Cre-recombinase |
| 89642 | Lenti-sgArid1a/Cre | Expresses an Arid1a-targeting gRNA and Cre-recombinase |
| 89643 | Lenti-sgAtm/Cre | Expresses an Atm-targeting gRNA and Cre-recombinase |
| 89644 | Lenti-sgCdkn2a/Cre | Expresses a Cdkn2a-targeting gRNA and Cre-recombinase |
| 89645 | Lenti-sgKeap1/Cre | Expresses a Keap1-targeting gRNA and Cre-recombinase |
| 89646 | Lenti-sgp53/Cre | Expresses a p53-targeting gRNA and Cre-recombinase |
| 89647 | Lenti-sgRb1/Cre | Expresses an Rb1-targeting gRNA and Cre-recombinase |
| 89648 | Lenti-sgRbm10/Cre | Expresses an Rbm10-targeting gRNA and Cre-recombinase |
| 89649 | Lenti-sgSetd2#1/Cre | Expresses a Setd2-targeting gRNA and Cre-recombinase |
| 89650 | Lenti-sgSetd2#2/Cre | Expresses a Setd2-targeting gRNA and Cre-recombinase |
| 89651 | Lenti-sgSmad4/Cre | Expresses a Smad4-targeting gRNA and Cre-recombinase |
| 89652 | Lenti-sgNeo2/Cre | Expresses a Neomycin-targeting gRNA and Cre-recombinase |
| 89653 | Lenti-sgNeo3/Cre | Expresses a Neomycin-targeting gRNA and Cre-recombinase |
| 89654 | Lenti-sgNT3/Cre | Expresses a non-targeting gRNA and Cre-recombinase |