Addgene: Distinct cellular toxicity of two mutant huntingtin mRNA variants due to translation regulation.

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Baoji Xu
Xu et al

Distinct cellular toxicity of two mutant huntingtin mRNA variants due to translation regulation.
Xu H, An JJ, Xu B
PLoS One. 2017 May 11;12(5):e0177610. doi: 10.1371/journal.pone.0177610. eCollection 2017. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
110486	Ultra-Exon1Q23-Myc-A	Lentiviral vector to express wild-type N terminal HTT gene with short 3'UTR in mammalian cells (encodes Myc-tagged wild type huntingtin exon1 fragment with 23 repeats of Q)
110487	Ultra-Exon1Q145-Myc-A	Lentiviral vector to express mutant N terminal HTT gene with short 3'UTR in mammalian cells (encodes Myc-tagged mutant huntingtin exon1 fragment with 145 repeats of Q)
110488	pUltra-Exon1Q23-Myc-B	Lentiviral vector to express wild-type N terminal HTT gene with partial long 3'UTR in mammalian cells (encodes Myc-tagged wild-type huntingtin exon1 fragment with 23 repeats of Q)
110489	pUltra-Exon1Q145-Myc-B	Lentiviral vector to express mutant N terminal HTT gene with partial long 3'UTR in mammalian cells (encodes Myc-tagged mutant huntingtin exon1 fragment with 145 repeats of Q)

Antibodies from Article