Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

Transmission of innate immune signaling by packaging of cGAMP in viral particles.
Gentili M, Kowal J, Tkach M, Satoh T, Lahaye X, Conrad C, Boyron M, Lombard B, Durand S, Kroemer G, Loew D, Dalod M, Thery C, Manel N
Science. 2015 Sep 11;349(6253):1232-6. doi: 10.1126/science.aab3628. Epub 2015 Jul 30.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
102597IFN-Beta_pGL3IFN-beta promoter driving luciferase. Use in IFN reporter assay.
Loading...
102602pTRIP-CMV-mTagBFP2-2AControl lentivector. Coexpression of mTagBFP and gene of interest from CMV promoter
Loading...
102603pTRIP-CMV-mTagBFP2-2A-FLAG-ntcGASLentivector to express Flag-tagged and shRNA-resistant cGAS and mTagBFP
Loading...
102604pTRIP-CMV-mtagBFP2-2A-FLAG-cGAS E225A/D227ALentivector to express Flag-tagged and catalytically-inactive cGAS and mTagBFP
Loading...
102605pcDNA3.1-Hygro(+)-PSTCD-cGASMammalian expression of cGAS fused to PSTCD tag
Loading...
102606pcDNA3.1-Hygro(+)-PSTCD-cGAS-delta DBDMammalian expression of mutant cGAS with deletion of DNA binding domain fused to PSTCD tag
Loading...
102607pcDNA3.1-Hygro(+)-mscGASMammalian expression of mouse cGAS
Loading...
102608pMSCV-hygro-STING R232Retroviral vector to expression STING R232
Loading...
102609pLCRISPR-CMVControl lentivector expressing Cas9 and gRNA scaffold
Loading...
102610pLCRISPR-CMV-cGAS3CRISPR/Cas9 lentivector targeting human cGAS
Loading...
102611pTRIP-CMV-Puro-2AControl lentivector expressing Puro resistance and gene of interest from CMV promoter
Loading...
102612pTRIP-CMV-Puro-2A-cGASLentivector expressing cGAS
Loading...