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Cleavage activates dispatched for Sonic Hedgehog ligand release.
Stewart DP, Marada S, Bodeen WJ, Truong A, Sakurada SM, Pandit T, Pruett-Miller SM, Ogden SK
Elife. 2018 Jan 23;7. pii: 31678. doi: 10.7554/eLife.31678. PubMed

Plasmids from Article

ID Plasmid Purpose
126405pAc V5 dDispatched WT HA Expression of V5 dDispatched WT HA in Drosophila cells lines.
126410pCDNA3 V5 mDispatched WT 2x HA Expression of V5 Dispatched WT HA in mammalian cell lines.
126411pUAS attB V5 dDispatched WT HAExpression of wild type dDispatched HA in Drosophila.
126412pUAS-attB V5 dDispatched delta CS HAExpression of V5 dDispatched Delta CS HA in Drosophila cells lines

Antibodies from Article