Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

Mutational processes shape the landscape of TP53 mutations in human cancer.
Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J, Howard TP, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B, Steelman S, Vazquez F, Tsherniak A, Aguirre AJ, Doench JG, Piccioni F, Roberts CWM, Meyerson M, Getz G, Johannessen CM, Root DE, Hahn WC
Nat Genet. 2018 Oct;50(10):1381-1387. doi: 10.1038/s41588-018-0204-y.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
113569TP53 MITE LibraryPooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53
Loading...
118014pLX313-TP53-WTConstitutive expression of wild-type human Tumor Protein p53 (TP53)
Loading...
118015pLX313-TP53-P278AConstitutive expression of mutant human Tumor Protein p53 (TP53)
Loading...
118016pLX313-Renilla luciferaseConstitutive expression of Renilla luciferase
Loading...
118017pLX313-Firefly luciferaseConstitutive expression of Firefly luciferase
Loading...
118018pLX311-Cas9Constitutive expression of Cas9
Loading...
118019pXPR003-sgTP53-1Constitutive expression of sgRNA targeting human TP53
Loading...
118020pXPR003-sgTP53-2Constitutive expression of sgRNA targeting human TP53
Loading...
118021pXPR003-sgTP53-3Constitutive expression of sgRNA targeting human TP53
Loading...
118022pXPR003-sgTP53-4Constitutive expression of sgRNA targeting human TP53
Loading...
118023pXPR003-sgTP53-5Constitutive expression of sgRNA targeting human TP53
Loading...

Recombinant Antibodies from Article