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Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering.
van der Schoot JMS, Fennemann FL, Valente M, Dolen Y, Hagemans IM, Becker AMD, Le Gall CM, van Dalen D, Cevirgel A, van Bruggen JAC, Engelfriet M, Caval T, Bentlage AEH, Fransen MF, Nederend M, Leusen JHW, Heck AJR, Vidarsson G, Figdor CG, Verdoes M, Scheeren FA
Sci Adv. 2019 Aug 28;5(8):eaaw1822. doi: 10.1126/sciadv.aaw1822. eCollection 2019 Aug.
PubMed Article

Plasmids from Article

ID Plasmid  
124802pHybr_r2a>mG1-srt-his
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124803pHybr_r2a>mG2a-srt-his
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124804pHybr_r2a>mG2b-srt-his
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124805pHybr_r2a>mG3-srt-his
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124806pHybr_r2a>mA-srt-his
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124807pHybr_r2a>m2a(silent)-srt-his
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124808PX458-gR2A_ISO
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124810pHybr_r2a>Fab-srt-his
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124811PX459-gR2A_Hinge
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