Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans.
Juttner J, Szabo A, Gross-Scherf B, Morikawa RK, Rompani SB, Hantz P, Szikra T, Esposti F, Cowan CS, Bharioke A, Patino-Alvarez CP, Keles O, Kusnyerik A, Azoulay T, Hartl D, Krebs AR, Schubeler D, Hajdu RI, Lukats A, Nemeth J, Nagy ZZ, Wu KC, Wu RH, Xiang L, Fang XL, Jin ZB, Goldblum D, Hasler PW, Scholl HPN, Krol J, Roska B
Nat Neurosci. 2019 Jul 8. pii: 10.1038/s41593-019-0431-2. doi: 10.1038/s41593-019-0431-2. PubMed Article
Juttner J, Szabo A, Gross-Scherf B, Morikawa RK, Rompani SB, Hantz P, Szikra T, Esposti F, Cowan CS, Bharioke A, Patino-Alvarez CP, Keles O, Kusnyerik A, Azoulay T, Hartl D, Krebs AR, Schubeler D, Hajdu RI, Lukats A, Nemeth J, Nagy ZZ, Wu KC, Wu RH, Xiang L, Fang XL, Jin ZB, Goldblum D, Hasler PW, Scholl HPN, Krol J, Roska B
Nat Neurosci. 2019 Jul 8. pii: 10.1038/s41593-019-0431-2. doi: 10.1038/s41593-019-0431-2. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 125886 | 136_pAAV-ProA1-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125887 | 137_pAAV-ProA3-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125888 | 155_pAAV-ProA4-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125889 | 88_pAAV-ProA5-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125890 | I_pAAV-ProA6-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125891 | VI_pAAV-ProA7-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125892 | 3_pAAV-ProA8-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125893 | 5_pAAV-ProA9-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125894 | 28_pAAV-ProA10-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125895 | 53_pAAV-ProA11-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125896 | 55_pAAV-ProA13-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125897 | 57_pAAV-ProA14-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125898 | 58_pAAV-ProA15-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125899 | 59_pAAV-ProA16-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125900 | 60_pAAV-ProA17-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125901 | 61_pAAV-ProA18-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125902 | 62_pAAV-ProA19-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125903 | 64_pAAV-ProA20-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125904 | 66_pAAV-ProA21-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125905 | 68_pAAV-ProA22-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125906 | 70_pAAV-ProA23-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125907 | 71_pAAV-ProA24-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125908 | 76_pAAV-ProA25-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125909 | 77_pAAV-ProA26-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125910 | 78_pAAV-ProA27-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125911 | 95_pAAV-ProA28-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125912 | 98_pAAV-ProA29-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125913 | 100_pAAV-ProA30-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125914 | 102_pAAV-ProA31-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125915 | 127_pAAV-ProA32-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125916 | 140_pAAV-ProA33-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125917 | 146_pAAV-ProA34-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125918 | 193_pAAV-ProA35-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125920 | 6_pAAV-ProA37-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125921 | 17_pAAV-ProB1-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125922 | 132_pAAV-ProB2-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125923 | IX_pAAV-ProB3-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125924 | III_pAAV-ProB4-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125925 | II_pAAV-ProB5-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125926 | IV_pAAV-ProB6-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125928 | VII_pAAV-ProB8-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125929 | VIII_pAAV-ProB9-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125930 | 7_pAAV-ProB10-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125931 | 26_pAAV-ProB11-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125932 | 27_pAAV-ProB12-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125933 | 131_pAAV-ProB13-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125934 | 169_pAAV-ProB14-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125935 | 194_pAAV-ProB15-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125937 | 123_pAAV-ProC1-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125938 | 12_pAAV-ProC2-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125939 | 124_pAAV-ProC3-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125940 | 8_pAAV-ProC4-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125941 | 9_pAAV-ProC5-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125942 | 11_pAAV-ProC6-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125943 | 35_pAAV-ProC8-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125944 | 40_pAAV-ProC9-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125945 | 45_pAAV-ProC10-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125946 | 46_pAAV-ProC11-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125947 | 51_pAAV-ProC12-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125948 | 82_pAAV-ProC13-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125949 | 83_pAAV-ProC14-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125950 | 104_pAAV-ProC15-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125951 | 105_pAAV-ProC16-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125952 | 107_pAAV-ProC17-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125953 | 108_pAAV-ProC18-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125954 | 109_pAAV-ProC19-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125955 | 110_pAAV-ProC20-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125956 | 113_pAAV-ProC21-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125957 | 114_pAAV-ProC22-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125958 | 115_pAAV-ProC23-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125959 | 116_pAAV-ProC24-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125960 | 119_pAAV-ProC25-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125961 | 120_pAAV-ProC26-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125962 | 121_pAAV-ProC27-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125964 | 151_pAAV-ProC29-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125965 | 152_pAAV-ProC30-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125966 | 153_pAAV-ProC31-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125968 | 167_pAAV-ProC34-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125969 | 168_pAAV-ProC35-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125970 | 171_pAAV-ProC36-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125971 | 172_pAAV-ProC37-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125972 | 173_pAAV-ProC38-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125973 | 174_pAAV-ProC39-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125974 | 37_pAAV-ProC40-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125975 | 42_pAAV-ProC41-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125976 | 13_pAAV-ProC71-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125977 | 198_pAAV-ProD1-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125978 | 157_pAAV-ProD2-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125979 | 159_pAAV-ProD3-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125980 | 160_pAAV-ProD4-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125981 | 161_pAAV-ProD5-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125984 | 177_pAAV-ProD8-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125985 | 178_pAAV-ProD9-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125986 | 179_pAAV-ProD10-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125987 | 180_pAAV-ProD11-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125988 | 181_pAAV-ProD12-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125989 | 182_pAAV-ProD13-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125990 | 183_pAAV-ProD14-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125991 | 184_pAAV-ProD15-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125992 | 185_pAAV-ProD16-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125993 | 206_pAAV-ProD17-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125994 | 209_pAAV-ProD18-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125995 | 210_pAAV-ProD19-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125996 | 211_pAAV-ProD20-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125997 | 212_pAAV-ProD21-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125998 | 214_pAAV-ProD22-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 125999 | 215_pAAV-ProD23-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126000 | 216_pAAV-ProD24-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126001 | 217_pAAV-ProD25-CatCh-GFP-WPRE | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126002 | pAAV-ProA1-GCaMP6s | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126003 | pAAV-ProA5-GCaMP6s | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126004 | pAAV-ProA18-GCaMP6s | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126005 | pAAV-ProD1-GCaMP6s | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |
| 126006 | pAAV2-ProC3-Cre/mCherry | Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina |