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Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.
Han H, Schubert HL, McCullough J, Monroe N, Purdy MD, Yeager M, Sundquist WI, Hill CP
J Biol Chem. 2019 Nov 25. pii: AC119.009890. doi: 10.1074/jbc.AC119.009890.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
128794pGEX-PP-Spastin(87-616)DeltaExon4Bacteiral expression of Spastin M87 varient without exon 4

Antibodies from Article