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Nuclear envelope rupture and repair during cancer cell migration.
Denais CM, Gilbert RM, Isermann P, McGregor AL, te Lindert M, Weigelin B, Davidson PM, Friedl P, Wolf K, Lammerding J
Science. 2016 Apr 15;352(6283):353-8. doi: 10.1126/science.aad7297. Epub 2016 Mar 24. PubMed Article

Plasmids from Article

ID Plasmid Purpose
132771pCDH-cGAS-E225A D227A-mCherry2-EF1-PuroInteracts with cytoplasmic DNA. Useful for identifying sites of nuclear envelope rupture.
132772pCDH-NLS-copGFP-EF1-BlastiSSpills into the cytoplasm during nuclear envelope rupture.

Antibodies from Article