Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity.
Kitakaze K, Taniuchi S, Kawano E, Hamada Y, Miyake M, Oyadomari M, Kojima H, Kosako H, Kuribara T, Yoshida S, Hosoya T, Oyadomari S
Elife. 2019 Dec 17;8. pii: 43302. doi: 10.7554/eLife.43302. PubMed Article
Kitakaze K, Taniuchi S, Kawano E, Hamada Y, Miyake M, Oyadomari M, Kojima H, Kosako H, Kuribara T, Yoshida S, Hosoya T, Oyadomari S
Elife. 2019 Dec 17;8. pii: 43302. doi: 10.7554/eLife.43302. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
159666 | lenti-25xAARE-minP-EGFP | EGFP reporter plasmid containing 25 tandem repeats of the amino acid response element (AARE) |
159667 | lenti-25xERSE2-minP-EGFP | EGFP reporter plasmid containing 25 tandem repeats of the ER stress response element-2 (ERSE2) |
159668 | lenti-25xUPRE-minP-EGFP | EGFP reporter plasmid containing 25 tandem repeats of the the unfolded protein response element (UPRE) |