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Addgene
A myosin-7B-dependent endocytosis pathway mediates cellular entry of alpha-synuclein fibrils and polycation-bearing cargos.
Zhang Q, Xu Y, Lee J, Jarnik M, Wu X, Bonifacino JS, Shen J, Ye Y
Proc Natl Acad Sci U S A. 2020 May 19;117(20):10865-10875. doi: 10.1073/pnas.1918617117. Epub 2020 May 4. PubMed Article

Plasmids from Article

ID Plasmid Purpose
154860Lenti-SLC35B2-sgRNALentiviral expression of Cas9 and sgRNA targeting SLC35B2
154861Lenti-Myosin7B-sgRNALentiviral expression of Cas9 and sgRNA targeting Myosin7B
154862Lenti-XYLT2-sgRNALentiviral expression of Cas9 and sgRNA targeting XYLT2
154863pLJM1-SLC35B2-FLAGTransient or Lentiviral expression of sgRNA (Addgene#154860) resistant SLC35B2
155037pEGFP-C-SLC35B2Transient expression of EGFP-SLC35B2
155038pVenus-N-SLC35B2Transient expression of SLC35B2-Venus

Antibodies from Article