Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer.
Sherekar M, Han SW, Ghirlando R, Messing S, Drew M, Rabara D, Waybright T, Juneja P, O'Neill H, Stanley CB, Bhowmik D, Ramanathan A, Subramaniam S, Nissley DV, Gillette W, McCormick F, Esposito D
J Biol Chem. 2020 Jan 24;295(4):1105-1119. doi: 10.1074/jbc.RA119.010934. Epub 2019 Dec 13. PubMed Article
Sherekar M, Han SW, Ghirlando R, Messing S, Drew M, Rabara D, Waybright T, Juneja P, O'Neill H, Stanley CB, Bhowmik D, Ramanathan A, Subramaniam S, Nissley DV, Gillette W, McCormick F, Esposito D
J Biol Chem. 2020 Jan 24;295(4):1105-1119. doi: 10.1074/jbc.RA119.010934. Epub 2019 Dec 13. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 159575 | R702-X80-635: His6-tev-Hs.NF1opt (1-2818) isoform 2 | Baculovirus protein expression of His6-tev-Hs.NF1opt (1-2818) isoform 2 |
| 159576 | R702-X38-635: His6-Hs.NF1opt (1-2839) isoform 1 | Baculovirus protein expression of His6-Hs.NF1opt (1-2839) isoform 1 |
| 159577 | R791-X12-636: His6-MBP-tev-Hs.NF1 ABC (2-1540) | Baculovirus protein expression of His6-MBP-tev-Hs.NF1 ABC (2-1540) |
| 159578 | R791-X15-636: His6-MBP-tev-Hs.NF1 DEF (1541-2818) | Baculovirus protein expression of His6-MBP-tev-Hs.NF1 DEF (1541-2818) |