Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.
Verardi R, Lindesmith LC, Tsybovsky Y, Gorman J, Chuang GY, Edwards CE, Brewer-Jensen PD, Mallory ML, Ou L, Schon A, Shi W, Tully ES, Georgiou G, Baric RS, Kwong PD
NPJ Vaccines. 2020 Dec 14;5(1):110. doi: 10.1038/s41541-020-00260-w. PubMed Article
Verardi R, Lindesmith LC, Tsybovsky Y, Gorman J, Chuang GY, Edwards CE, Brewer-Jensen PD, Mallory ML, Ou L, Schon A, Shi W, Tully ES, Georgiou G, Baric RS, Kwong PD
NPJ Vaccines. 2020 Dec 14;5(1):110. doi: 10.1038/s41541-020-00260-w. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 162579 | pFastBac1_GI.1_WT | Expresses norovirus GI.1 VP1 protein in Sf9 insect cells |
| 162580 | pFastBac1_GI.1_N116C-G193C | Expresses norovirus GI.1 VP1 protein with mutations N116C-G193C in Sf9 insect cells |
| 162581 | pFastBac1_GI.1_Q62C-A140C | Expresses norovirus GI.1 VP1 protein with mutations Q62C-A140C in Sf9 insect cells |
| 162582 | pFastBac1_GI.1_A37C-A44C | Expresses norovirus GI.1 VP1 protein with mutations A37C-A44C in Sf9 insect cells |
| 162583 | pFastBac1_GI.1_A37I-A44L | Expresses norovirus GI.1 VP1 protein with mutations A37I-A44L in Sf9 insect cells |
| 162584 | pFastBac1_GI.1_Q141V-P221L | Expresses norovirus GI.1 VP1 protein with mutations Q141V-P221L in Sf9 insect cells |
| 162585 | pFastBac1_GI.1_L144C-P221C | Expresses norovirus GI.1 VP1 protein with mutations L144C-P221C in Sf9 insect cells |
| 162586 | pFastBac1_GI.1_G131C-N172C | Expresses norovirus GI.1 VP1 protein with mutations G131C-N172C in Sf9 insect cells |
| 162587 | pFastBac1_GI.1_N167C-L169C | Expresses norovirus GI.1 VP1 protein with mutations N167C-L169C in Sf9 insect cells |