Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration.
Yang Q, Hughes TA, Kelkar A, Yu X, Cheng K, Park S, Huang WC, Lovell JF, Neelamegham S
Elife. 2020 Oct 26;9. pii: 61552. doi: 10.7554/eLife.61552. PubMed Article
Yang Q, Hughes TA, Kelkar A, Yu X, Cheng K, Park S, Huang WC, Lovell JF, Neelamegham S
Elife. 2020 Oct 26;9. pii: 61552. doi: 10.7554/eLife.61552. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164219 | ACE2 | Expresses full length human ACE2 protein, along with TagBFP reporter and Puromycin selection marker |
| 164220 | S1-Fc | Expresses soluble, dimeric Fc-His fusion protein for the original SARS-CoV2 Spike S1 region, along with dTomato reporter |
| 164221 | RBD-Fc | Expresses soluble , dimeric Fc-His fusion protein for the original SARS-CoV2 Spike RBD region, along with dTomato reporter |
| 164222 | ACE2-Fc | Expresses soluble , dimeric Fc-His fusion protein for the human ACE2 extracellular domain, along with dTomato reporter |