T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD
Science. 2017 Mar 31;355(6332):1428-1433. doi: 10.1126/science.aaf1292. Epub 2017 Mar 9. PubMed Article
Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD
Science. 2017 Mar 31;355(6332):1428-1433. doi: 10.1126/science.aaf1292. Epub 2017 Mar 9. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 177896 | pET28a(His10-PD-1cyto) | E coli expression of His10 tag fused to human PD-1 Intracellular Domain |
| 177897 | pFastBac (GST-SNAP-Shp2) | Baculo expression of GST tag fused to SNAP tag and human Shp2 |
| 177899 | pFastBac(His10-Shp2) | Baculo expression of His10 tag fused to human Shp2 |
| 177900 | pET28a(cd226) | Bacterial expression of his10-tagged human cd226 Intracellular Domain |
| 177901 | pET28a(cd96) | Bacterial expression of his10-tagged human cd96 Intracellular Domain |
| 177902 | pET28a(TIGIT) | Bacterial expression of his10-tagged human TIGIT Intracellular Domain |
| 177903 | pET28a(ICOS) | Bacterial expression of his10-tagged human ICOS Intracellular Domain |
| 177904 | pET28a(DAP10) | Bacterial expression of his10-tagged human DAP10 Intracellular Domain |
| 177905 | pET28a(CTLA4) | Bacterial expression of his10-tagged human CTLA4 Intracellular Domain |
| 177907 | pGEX6P2(GST-SNAP-Shp2tSH2) | Baculo expression of GST tag fused to SNAPtag and human Shp2 tandem SH2 domains |