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Molecular basis of astrocyte diversity and morphology across the CNS in health and disease.
Endo F, Kasai A, Soto JS, Yu X, Qu Z, Hashimoto H, Gradinaru V, Kawaguchi R, Khakh BS
Science. 2022 Nov 4;378(6619):eadc9020. doi: 10.1126/science.adc9020. Epub 2022 Nov 4. PubMed Article

Plasmids from Article

ID Plasmid Purpose
178960PZac2.1 gfaABC1D-NLS-SaCas9-3xHA-NLS bGHExpresses saCas9 protein specifically in astrocytes
179117Pzac2.1 U6-Fermt2 sgRNA1, 2, 3_gfaABC1D mcherry SV40Expresses Fermt2 sgRNAs under the U6 promoter and mcherry protein specifically in astrocytes
179119Pzac2.1 U6-Ezr sgRNA1, 2, 3_gfaABC1D mcherry SV40Expresses Ezr sgRNAs under the U6 promoter and mcherry protein specifically in astrocytes
179120Pzac2.1 U6-control sgRNA1, 2, 3_gfaABC1D mcherry SV40Expresses control sgRNAs under the U6 promoter and mcherry protein specifically in astrocytes

Antibodies from Article