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A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments.
Qian T, Wang H, Wang P, Geng L, Mei L, Osakada T, Wang L, Tang Y, Kania A, Grinevich V, Stoop R, Lin D, Luo M, Li Y
Nat Biotechnol. 2023 Jan 2. doi: 10.1038/s41587-022-01561-2.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
185384pDisplay-GRAB_OT1.0Expresses the genetically-encoded fluorescent oxytocin(OT) sensor GRAB_OT1.0 in mammalian cells
185385pDisplay-GRAB_OTmutExpresses the genetically-encoded fluorescent oxytocin(OT) control sensor GRAB_OTmut in mammalian cells
185386pAAV-hSyn-GRAB_OT1.0Expresses the genetically-encoded fluorescent oxytocin(OT) sensor GRAB_OT1.0 in neurons
185387pAAV-EFS-DIO-GRAB_OT1.0Expresses the genetically-encoded fluorescent oxytocin(OT) sensor GRAB_OT1.0 in a cre-dependent manner
185388pAAV-hSyn-GRAB_OTmutExpresses the genetically-encoded fluorescent oxytocin(OT) control sensor GRAB_OTmut in neurons
185389pAAV-EFS-DIO-GRAB_OTmutExpresses the genetically-encoded fluorescent oxytocin(OT) sensor GRAB_OT1.0 in a cre-dependent manner

Antibodies from Article