Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.
Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D
Nat Commun. 2022 May 19;13(1):2769. doi: 10.1038/s41467-022-30236-4. PubMed Article
Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D
Nat Commun. 2022 May 19;13(1):2769. doi: 10.1038/s41467-022-30236-4. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 185645 | pEGFP-NDUFA2-mVenus | NDUFA2 Complex I sub-unit with C-terminus mVenus tag |
| 185646 | pEGFP-NDUFA5-mVenus | NDUFA5 Complex I sub-unit with C-terminus mVenus tag |
| 185647 | pEGFP-NDUFA7-mVenus | NDUFA7 Complex I sub-unit with C-terminus mVenus tag |
| 185648 | pEGFP-NDUFA10-mVenus | NDUFA10 Complex I sub-unit with C-terminus mVenus tag |
| 185649 | pEGFP-NDUFS3-mVenus | NDUFS3 Complex I sub-unit with C-terminus mVenus tag |
| 185652 | pEGFP-NDUFB6-mVenus | NDUFB6 Complex I sub-unit with C-terminus mVenus tag |
| 185653 | pEGFP-NDUFV2-mVenus | NDUFV2 Complex I sub-unit with C-terminus mVenus tag |
| 185657 | pCW57.1-MCU-Flag-TetOFF | Tet/dox-repressible expression of C-terminus Flag tagged human mitochondrial calcium uniporter |
| 185658 | pLenti-mitoX4-FKBP-HA | Mitochondrial targetted (Cox8) FKBP protein with C-terminal HA epitope |
| 185659 | pCW57.1-FRB-MCU-Flag-TetOFF | Tet/dox-repressible expression of N-terminus FRB tagged human mitochondrial calcium uniporter with C-terminus Flag epitope |
| 185806 | pEGFP-NDUFS6-mVenus | NDUFS6 Complex I sub-unit with C-terminus mVenus tag |
| 185807 | pLenti-mitoX4-mCerulean | Mitochondrial targetted (COX8) mCerulean |
| 185808 | pLenti-mitoX4-mVenus | Mitochondrial targetted (COX8) mVenus |
| 185809 | pLenti-MCU-mCerulean | Human mitochondrial calcium uniporter with C-terminus mCerulean tag |
| 185810 | pLenti-NDUFA10-FKBP-HA | NDUFA10 subunit of Complex I fused with C-terminal FKBP and HA epitope |