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Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases.
Cho SI, Lee S, Mok YG, Lim K, Lee J, Lee JM, Chung E, Kim JS
Cell. 2022 May 12;185(10):1764-1776.e12. doi: 10.1016/j.cell.2022.03.039. Epub 2022 Apr 25. PubMed Article

Plasmids from Article

ID Plasmid Purpose
183892TALED_Left-ND1-1397C-ADExpresses TALED_Left-ND1-1397C-AD in mammalian cells
183893TALED_Left-ND1-1397C-UGIExpresses TALED_Left-ND1-1397C-UGI in mammalian cells
183894TALED_Left-ND1-AD-E1347AExpresses TALED_Left-ND1-AD-E1347A in mammalian cells
183895TALED_Left-ND1-E1347AExpresses TALED_Left-ND1-E1347A in mammalian cells
183896TALED_Left-RNR2-1397C-ADExpresses TALED_Left-RNR2-1397C-AD in mammalian cells
183897TALED_Right-RNR2-1397NExpresses TALED_Right-RNR2-1397N in mammalian cells
183898TALED_Right-ND1-1397NExpresses TALED_Right-ND1-1397N in mammalian cells
183899TALED_Right-ND1-1397N-UGIExpresses TALED_Right-ND1-1397N-UGI in mammalian cells
183900TALED_Right-ND1-ADExpresses TALED_Right-ND1-AD in mammalian cells
187161TALED_Left-stuffer-E1347Aoriginal vector to make all constructs
187162TALED_Left-stuffer-8eoriginal vector to make all constructs
187163TALED_Left-stuffer-8e-E1347Aoriginal vector to make all constructs
187164TALED_Right-stuffer-E1347Aoriginal vector to make all constructs
187165TALED_Right-stuffer-8eoriginal vector to make all constructs
187166TALED_Right-stuffer-8e-E1347Aoriginal vector to make all constructs
187167TALED_Left-stuffer-1397Noriginal vector to make all constructs
187168TALED_Left-stuffer-1397C-UGIoriginal vector to make all constructs
187169TALED_Left-stuffer-1397C-8eoriginal vector to make all constructs
187170TALED_Right-stuffer-1397C-8eoriginal vector to make all constructs
187171TALED_Right-stuffer-1397C-UGIoriginal vector to make all constructs
187172TALED_Right-stuffer-1397Noriginal vector to make all constructs
187173TALED_Right-stuffer-1397N-UGIoriginal vector to make all constructs
187174TALED_Left-stuffer-1397N-UGIoriginal vector to make all constructs

Antibodies from Article