CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade.
Wang G, Chow RD, Zhu L, Bai Z, Ye L, Zhang F, Renauer PA, Dong MB, Dai X, Zhang X, Du Y, Cheng Y, Niu L, Chu Z, Kim K, Liao C, Clark P, Errami Y, Chen S
Cancer Discov. 2020 Dec;10(12):1912-1933. doi: 10.1158/2159-8290.CD-19-1448. Epub 2020 Sep 4. PubMed Article
Wang G, Chow RD, Zhu L, Bai Z, Ye L, Zhang F, Renauer PA, Dong MB, Dai X, Zhang X, Du Y, Cheng Y, Niu L, Chu Z, Kim K, Liao C, Clark P, Errami Y, Chen S
Cancer Discov. 2020 Dec;10(12):1912-1933. doi: 10.1158/2159-8290.CD-19-1448. Epub 2020 Sep 4. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 192162 | pGW02 AAV-TBG-Cre-sgP53-sgRNA | AAV-TBG-Cre-sgP53-sgRNA |
| 192163 | pGW03 AAV-TBG-Cre-sgRNA | AAV-TBG-Cre-sgRNA |
| 192164 | AAV-TBG-Cre-sgKmt2d | AAV-TBG-Cre-sgKmt2d |
| 192165 | AAV-TBG-Cre-sgArid1a | AAV-TBG-Cre-sgArid1a |
| 192166 | Lenti-sgKmt2d-sg1 | Lenti-sgKmt2d-sg1 |
| 192167 | Lenti-sgKmt2d-sg3 | Lenti-sgKmt2d-sg3 |
| 192169 | Lenti-sgArid1a-sg3 | Lenti-sgArid1a-sg3 |