Addgene: Optogenetic activators of apoptosis, necroptosis, and pyroptosis.

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Petr Broz
Shkarina et al

Optogenetic activators of apoptosis, necroptosis, and pyroptosis.
Shkarina K, Hasel de Carvalho E, Santos JC, Ramos S, Leptin M, Broz P
J Cell Biol. 2022 Jun 6;221(6). pii: 213145. doi: 10.1083/jcb.202109038. Epub 2022 Apr 14. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
208780	pLVX-Cry2olig	Inducibly expresses light activatable Cry2 domain
208781	pLVX-opto-mCasp1	Inducibly expresses mouse caspase1 fused to light activatable Cry2
208782	pLVX-opto-mCasp8	Inducibly expresses mouse caspase8 fused to light-activatable Cry2
208783	pLVX-opto-mRipK3	Inducibly expresses mouse RipK3 fused to light activatable Cry2
208784	pLVX-opto-mMLKL	Inducibly expresses mouse MLKL fused to light-activatable Cry2
208785	pLVX-opto-hCaspase-4 dCARD	Inducibly expresses human Caspase 4 lacking the CARD domain, fused to light-activatable Cry2
208786	pLVX-opto-hCaspase-8	Inducibly expresses human Caspase 8 fused to light-activatable Cry2
208787	pLVX-opto-hCaspase-9	Inducibly expresses human Caspase 8 fused to light-activatable Cry2
208788	pLVX-opto-hRIP3 dRHIM	Inducibly expresses human RIP3, lacking RHIM domain, fused to light-activatable Cry2
208789	pLVX-opto-hMLKL	Inducibly expresses human MLKL, fused to light-activatable Cry2
208790	pLVX-opto-hCaspase-1	Inducibly expresses human Caspase1, fused to light-activatable Cry2

Antibodies from Article