Multidimensional control of therapeutic human cell function with synthetic gene circuits.
Li HS, Israni DV, Gagnon KA, Gan KA, Raymond MH, Sander JD, Roybal KT, Joung JK, Wong WW, Khalil AS
Science. 2022 Dec 16;378(6625):1227-1234. doi: 10.1126/science.ade0156. Epub 2022 Dec 15. PubMed Article
Li HS, Israni DV, Gagnon KA, Gan KA, Raymond MH, Sander JD, Roybal KT, Joung JK, Wong WW, Khalil AS
Science. 2022 Dec 16;378(6625):1227-1234. doi: 10.1126/science.ade0156. Epub 2022 Dec 15. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 195413 | pMN-009 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF1 |
| 195414 | pMN-010 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF2 |
| 195415 | pMN-011 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF3 |
| 195416 | pMN-012 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF4 |
| 195417 | pMN-013 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF5 |
| 195418 | pMN-014 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF6 |
| 195419 | pMN-015 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF7 |
| 195420 | pMN-016 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF8 |
| 195421 | pMN-017 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF9 |
| 195422 | pMN-018 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF10 |
| 195423 | pMN-019 | AAVS1 Integratable mCherry Reporter for synZiFTR ZF11 |
| 195424 | pMZ-176 | Transient, constitutive expression of synZiFTR: ZF1-p65 |
| 195425 | pMZ-177 | Transient, constitutive expression of synZiFTR: ZF2-p65 |
| 195426 | pMZ-178 | Transient, constitutive expression of synZiFTR: ZF3-p65 |
| 195427 | pMZ-179 | Transient, constitutive expression of synZiFTR: ZF4-p65 |
| 195428 | pMZ-180 | Transient, constitutive expression of synZiFTR: ZF5-p65 |
| 195429 | pMZ-181 | Transient, constitutive expression of synZiFTR: ZF6-p65 |
| 195430 | pMZ-182 | Transient, constitutive expression of synZiFTR: ZF7-p65 |
| 195431 | pMZ-183 | Transient, constitutive expression of synZiFTR: ZF8-p65 |
| 195432 | pMZ-184 | Transient, constitutive expression of synZiFTR: ZF9-p65 |
| 195433 | pMZ-185 | Transient, constitutive expression of synZiFTR: ZF10-p65 |
| 195434 | pMZ-186 | Transient, constitutive expression of synZiFTR: ZF11-p65 |
| 195435 | pO-066 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195436 | pO-081 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195437 | pO-070 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195438 | pMN-258 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195439 | pMN-259 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195440 | pMN-260 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195441 | pMN-322 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195442 | pMN-323 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195443 | pMN-324 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195444 | pMN-316 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195445 | pMN-317 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195446 | pMN-318 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195447 | pMN-319 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195448 | pMN-320 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195449 | pMN-321 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195450 | pMN-325 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195451 | pMN-326 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195452 | pMN-327 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195453 | pMN-294 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF1 |
| 195454 | pMN-296 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF3 |
| 195455 | pMN-303 | Lentiviral Integratable mCherry Reporter for synZiFTR ZF10 |
| 195456 | pMZ-345 | Lentiviral Integratable, constitutive expression of synZiFTR: ZF1-p65 |
| 195457 | pMZ-346 | Lentiviral Integratable, constitutive expression of synZiFTR: ZF3-p65 |
| 195458 | pMZ-347 | Lentiviral Integratable, constitutive expression of synZiFTR: ZF10-p65 |
| 195459 | pMZ-314 | Lentiviral Integratable, ABA-inducible expression of synZiFTR: ZF1-p65 |
| 195460 | pHS_235 | Lentiviral Integratable, 4OHT/TMX-inducible expression of synZiFTR: ZF3-p65 |
| 195461 | pHS-139 | Lentiviral Integratable, GZV-inducible expression of synZiFTR: ZF10-p65 |
| 195462 | pMZ-431 | Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: ZF3-p65 |
| 195463 | pMZ-432 | Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: ZF3-p65 |
| 195464 | pMZ-440 | Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: KRAB-ZF3 |
| 195465 | pMZ-441 | Lentiviral Integratable, 4OHT/TMX- and GZV-controllable expression of synZiFTR: HP1a-ZF3 |
| 195466 | pMN-332 | Lentiviral Integratable Inducible synZiFTR ZF1 + Reporter |
| 195467 | pMN-333 | Lentiviral Integratable Inducible synZiFTR ZF3 + Reporter |
| 195468 | pMN-334 | Lentiviral Integratable Inducible synZiFTR ZF10 + Reporter |
| 195469 | pBW-507 | Lentiviral Integratable Constitutive CD19CAR |
| 195470 | pHS-435 | Lentiviral Integratable Constitutive super IL-2 cytokine |
| 195471 | pHS-439 | Lentiviral Integratable Inducible superIL-2 cytokine using synZiFTR ZF3 |
| 195472 | pMN-285 | Lentiviral Integratable Inducible CD19CAR using synZiFTR ZF10 |
| 195473 | pHS-393 | Lentiviral Integratable Inducible super-IL2 cytokine + synZiFTR10 |