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Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth.
Sharma A, Mistriel-Zerbib S, Najar RA, Engal E, Bentata M, Taqatqa N, Dahan S, Cohen K, Jaffe-Herman S, Geminder O, Baker M, Nevo Y, Plaschkes I, Kay G, Drier Y, Berger M, Salton M
PLoS Biol. 2023 Jun 28;21(6):e3002175. doi: 10.1371/journal.pbio.3002175.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
210621pSPgRNA_-60_Enh_1gRNA target sequences for TAL1 -60 Enhancer
210622pSPgRNA_-60_Enh_2gRNA target sequences for TAL1 -60 Enhancer
210623pSPgRNA_-60_Enh_3gRNA target sequences for TAL1 -60 Enhancer
210624pSPgRNA_-60_Enh_4gRNA target sequences for TAL1 -60 Enhancer
210625pSPgRNA_Ex3_1gRNA target sequences for TAL1 Exon 3
210626pSPgRNA_Ex3_2gRNA target sequences for TAL1 Exon 3
210627pSPgRNA_Ex3_3gRNA target sequences for TAL1 Exon 3
210628pSPgRNA_Ex3_4gRNA target sequences for TAL1 Exon 3
210629pGL4.23_Promoter_1-3Luciferase experiment for TAL1 promoter 1-3
210632pGL4.23_Promoter_5Luciferase experiment for TAL1 promoter 5
210633pGL4.23_TSS1Luciferase experiment for TAL1 TSS1
210634pGL4.23_TSS2Luciferase experiment for TAL1 TSS2
210635pGL4.23_TSS4Luciferase experiment for TAL1 TSS4
210636pGL4.23_TSS5Luciferase experiment for TAL1 TSS5
210637MIGR1_FLAG_TAL1-short_GFPOverexpression of TAL1-short
210638MIGR1_FLAG_TAL1-long_GFPOverexpression of TAL1-long
210639MIGR1_FLAG_TAL1-long_dt tomatoOverexpression of TAL1-long
210640Tet-pLKO-puro-shTAL1Knockdown of TAL1 endogenous (3'UTR)
210641pLenti-CMV-GFP-Puro_TAL1-shortOverexpression of TAL1-short

Antibodies from Article