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An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming.
Weng M, Hu H, Graus MS, Tan DS, Gao Y, Ren S, Ho DHH, Langer J, Holzner M, Huang Y, Ling GS, Lai CSW, Francois M, Jauch R
Sci Adv. 2023 Aug 25;9(34):eadh2501. doi: 10.1126/sciadv.adh2501. Epub 2023 Aug 23.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
206384pHAGE2-TetO-hSOX17FNV Expresses human SOX17FNV in mammalian cells, for lentivirus generation.
206385pHAGE2-TetO-hSOX2-C17Expresses human SOX2-C17 in mammalian cells, for lentivirus generation.
206386pHAGE2-TetO-hKLF4Expresses human KLF4 in mammalian cells, for lentivirus generation.
206387pHAGE2-TetO-hcMYCExpresses human c-MYC in mammalian cells, for lentivirus generation.
206388pHAGE2-TetO-hSOX2Expresses human SOX2 in mammalian cells, for lentivirus generation.
206389pHAGE2-TetO-hSOX17Expresses human SOX17 in mammalian cells, for lentivirus generation.
206390pLVTHM-mBrn2-3xflagExpresses 3xflag fused mouse BRN2 in mammalian cells, for lentivirus generation.
206391Halo-tagged Sox17FNV Expresses Halo-tagged mouse SOX17FNV in mammalian cells, for single-molecule tracking.

Antibodies from Article