Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release.
Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T, Sessa WC
Circ Res. 2002 May 3. 90(8):866-73. PubMed Article
Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T, Sessa WC
Circ Res. 2002 May 3. 90(8):866-73. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 22481 | GST-Hsp90 N(9-236) | |
| 22482 | GST-Hsp90 M(272-617) | Please note this plasmid contains GST-Hsp90 residues 273-617. |
| 22483 | GST-Hsp90 C(626-732) |