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Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.
Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA
Hum Mol Genet. 1999 May . 8(5):731-41.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
28235pEGFP-C1-ARMammalian expression of Androgen receptor fused to EGFP
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86427pEGFP-C1-AR Q0Fluorescent human androgen receptor (fused to EGFP) with deleted polyglutamine region
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86428pEGFP-C1-AR Q48Fluorescent human androgen receptor (fused to EGFP) with expanded polyglutamine region
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