An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders.
Baker SA, Chen L, Wilkins AD, Yu P, Lichtarge O, Zoghbi HY
Cell. 2013 Feb 28;152(5):984-96. doi: 10.1016/j.cell.2013.01.038. PubMed Article
Baker SA, Chen L, Wilkins AD, Yu P, Lichtarge O, Zoghbi HY
Cell. 2013 Feb 28;152(5):984-96. doi: 10.1016/j.cell.2013.01.038. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 48078 | pDEST-hMeCP2-GFP | Mammalian expression of GFP tagged MeCP2-WT |
| 48079 | pDEST-hMeCP2-GFP-R270X | Mammalian expression of GFP tagged MeCP2-R270X |
| 48080 | pDEST-hMeCP2-GFP-G273X | Mammalian expression of GFP tagged MeCP2-G273X |
| 48081 | pUAS-hActin-luc2 | Luciferase Reporter with Gal4 DNA binding site upstream of hACTB promoter |
| 48082 | pCMX-Gal4-hMeCP2 | Mammalian expression of Gal4 tagged MeCP2-WT |
| 48083 | pCMX-Gal4-hMeCP2-R270X | Mammalian expression of Gal4 tagged MeCP2-R270X |
| 48084 | pCMX-Gal4-hMeCP2-G273X | Mammalian expression of Gal4 tagged MeCP2-G273X |
| 48085 | pCMX-Gal4-hMeCP2-R111G | Mammalian expression of Gal4 tagged MeCP2-WT-R111G |
| 48086 | pCMX-Gal4-hMeCP2-R270X-R111G | Mammalian expression of Gal4 tagged MeCP2-R270X-R111G |
| 48087 | pCMX-Gal4-hMeCP2-G273X-R111G | Mammalian expression of Gal4 tagged MeCP2-G273X-R111G |
| 48089 | pGEX-5x3-hMeCP2-delN256-R270X | Bacterial expression of GST tagged AT-Hook2-R270X |
| 48090 | pGEX-5x3-hMeCP2-delN256-G273X | Bacterial expression of GST tagged AT-Hook2-G273X |
| 48091 | pTXB1-hMeCP2 | Bacterial expression of Mxe intein/chitin binding domain tagged MeCP2-WT |
| 48092 | pTXB1-hMeCP2-R270X | Bacterial expression of Mxe intein/chitin binding domain tagged MeCP2-R270X |
| 48093 | pTXB1-hMeCP2-G273X | Bacterial expression of Mxe intein/chitin binding domain tagged MeCP2-G273X |